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Cell Metabolism: Glucagon, just a glycemic hormone? Do you really know about glucagon
Time of Update: 2023-01-04
Mechanism of glucagon secretion in hypoglycemic responseSevere hypoglycemia is an acute, life-threatening condition primarily associated with severe drops in blood glucose levels associated with insulin therapy, most commonly in people with type 1 diabetes caused by daily insulin injections.
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Cell reveals the neurobiological mechanism by which the brain initiates the "nausea-vomiting" response
Time of Update: 2022-11-25
The laboratory of Beijing Institute of Biological Sciences/Tsinghua University Institute of Biomedical Sciences has established a new paradigm for studying the "nausea-vomiting" response using mice as animal models, and preliminarily revealed the molecular cell and neural circuit mechanism of the brain sensing pathogenic invasion and initiating the "nausea-vomiting" response.
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Saiye animal models helped Sun Yat-sen University and other teams discover potential therapeutic targets for KRAS mutated cancers
Time of Update: 2022-11-15
Recently, researchers from the First Affiliated Hospital of Sun Yat-sen University and Nanjing University have found that a protein RASON encoded by a long chain of non-coding RNA between genes (LINC00673) is a key regulator of the oncogenic RAS signaling pathway and is expected to become a therapeutic target for KRAS mutated cancers.
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Cell research Shanghai Drug revealed the structural basis of frogetin family receptors to recognize itch polypeptides
Time of Update: 2022-11-14
On November 3, 2022, the team of Xu Huaqiang/Yin Wanchao of the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, published the research results entitled "Molecular recognition of itch-associated neuropeptides by bombesin receptors" online on Cell Research 。 This achievement is the first to report that the frogetin family receptor Neuromedin B receptor (NMBR) and Gastrin-releasing peptide receptor (GRPR) bind endogenous polypeptide ligands - neuromedin B (NMB) and gastrin-releasing peptide (GRP), respectively.
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Issue 13/2019 - Saudi Aramco partners with Air Products to open hydrogen fuel station
Time of Update: 2022-11-11
The new test station combines Saudi Aramco's industrial technology experience with Air Products' expertise and experience in hydrogen fuels.
The new test station combines Saudi Aramco's industrial technology experience with Air Products' expertise and experience in hydrogen fuels.
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To infect the brain, fungi evolved from bird droppings
Time of Update: 2022-09-21
According to the latest research by scientists at the University of Utah Health Center, a fungus is a common cause of fungal meningitis, and once it enters the human body, it undergoes a significant shift that infects the brain.
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An innovative analysis solution for neuronal structure and activity: long-term + real-time quantification
Time of Update: 2022-08-30
Analyzing a single endpoint (such as immunohistochemistry) during the entire process of neuronal maturation is not only impossible to perform repetitive kinetic assessments, but also requires tedious steps for fixing, staining, rinsing, collecting and analyzing images;Nor can it be combined with the physiologically relevant environment to obtain comprehensive information;Unable to confirm cellular morphology, spatial resolution, or assess functional connectivity;Only a limited number of cells can be measured, and the real network environment cannot be simulated .
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JECCR Zhengzhou University Professor Wei Cao’s team reveals a new mechanism for the occurrence of esophageal squamous cell carcinoma
Time of Update: 2021-09-30
On September 21, 2021, Professor Cao Wei’s team from Zhengzhou Central Hospital Affiliated to Zhengzhou University and Professor Guan Fangxia’s research group from the School of Life Sciences of Zhengzhou University jointly published the title "RNA m6A demethylase FTO-mediated epigenetic up-regulation" in the Journal of Experimental&Clinical Cancer Research.
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Chinese scientists 'portrait' cells of 15 types of tumors
Time of Update: 2021-02-10
By further integrating the single-cell transcription group sequencing data produced by the team and published public data, the team constructed a map of myelin cells for 15 cancer species, including stomach cancer, and systematically compared the differences in the composition, development and function of myelin cell groups between different cancer species.
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The first antibody drug to target BCMA, Blenrep, was approved by the FDA for accelerated treatment of recurrent or recurrent multiple myeloma
Time of Update: 2020-08-22
GlaxoSmithKline announced that the FDA has accelerated approval of Belantamab mafodotin-blmf for the treatment of adult patients with recurrent or recurrent multiple myeloma who have received at least four previous treatments, including anti-CD38 monoclonal antibodies, protease inhibitors, and immunomodants.
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Cell . . . Create a visual network map of the cerebrovascular vessels
Time of Update: 2020-07-22
the cerebral vascular system spans multiple scales, ranging from microns of capillaries to a few millimeters of blood vessels, forming a highly complex network.
