Lancet: Nasal mucosal immunity is a key factor in the protection of the new crown
Time of Update: 2023-02-01
Figure 1 PROBABILITY OF SYMPTOMATIC ILLNESS CAUSED BY VIRAL LOAD (SOURCE: LANCET INFECT DIS)The nasopharynx is the first site where the new coronavirus invades the human body, and the nasal antibody IgA produced by mucosal immunity is the most abundant mucosal antibody, which plays an important role in effectively neutralizing the upper respiratory tract virus.
Nature: This brain cell cooperates with the gut microbiome to fight brain inflammation
Time of Update: 2022-10-08
"The discovery of this anti-inflammatory subpopulation of astrocytes controlled by gut microbes is an important advance in our understanding of CNS inflammation and its regulation," said the researchers .
Nasal spray-releasing peptide reduces seizure activity, protects neurons in Alzheimer's disease, epilepsy
Time of Update: 2022-08-19
Image: Dr. Qin Wang (middle) and his MCG research team Image credit: Michael Holahan, Augusta UniversityIn research models of Alzheimer's disease and epilepsy, a novel peptide enhances the brain's natural mechanisms to help prevent epilepsy and protect neurons, scientists report .
Cell sub-journal: Bifidobacterium promotes the maturation of intestinal flora in extremely premature infants
Time of Update: 2022-08-10
Cell Host & Microbe published an article describing the use of a mixed formula containing Bifidobacterium and Lactobacillus (Bifidobacterium breve HA-129, Bifidobacterium bifidum HA-132, Bifidobacterium infantis HA-116, Bifidobacterium longum HA-135, Lactobacillus rhamnosus HA-111), can repair the intestinal microecology of extremely premature infants, promote the maturation of the flora to the level of full-term infants, and reduce the inflammatory response .
Front Aging Neurosci︱Ma Tao's team reveals the mechanism of Chinese herbal compound multi-pathway and multi-target improving energy metabolism in Alzheimer's disease
Time of Update: 2022-06-08
Through action network analysis, the researchers found: 5 protein targets including DAO, HIF1A, ALDH3B2, PARP1 and ACHE, 14 differential metabolites such as pyruvate and L-lactate, and TCA cycle, glycolysis, niacin/nicotinamide Four metabolic pathways including metabolism and glycerophospholipid metabolism play key roles in the intervention of Dihuang Yinzi on APP/PS1 mice .
Bacterial indoles as multifunctional modulators of complex enterotoxicity in Klebsiella oxytocins
Time of Update: 2022-02-17
PXR is a ligand-activated host nuclear receptor that plays an important role in exogenous detoxification (13) PXR also modulates intestinal inflammatory responses by binding to microbe-specific indoles (12).
Br J Cancer: HPV-positive oropharyngeal squamous cell carcinoma changes to the gut microbiome after radiotherapy and chemotherapy
Time of Update: 2021-03-19
In this study, the researchers analyzed the oral and intestinal microbiome in the cohort of HPV+OPSCC patients and evaluated the impact of radiotherapy and chemotherapy (CRT).
J Clin Invest: Study uncovers the pathogenic effects γ intestinal vascular activation mediated by IFN-2000
Time of Update: 2020-10-11
these considerations, we analyzed ifN-γ's vascular-directed pathogenicity and found that it drives the onset of IBD by breaking the vascular barrier.
, the findings shed light on the pathogenic effects of IFN-γ-mediated intestinal vascular activation in IBD and opened up new avenues for vascular-oriented treatment of the disease.
GUT: Western diets can affect necrotitis mortality
Time of Update: 2020-10-04
The preventive effects of necrotized pancreatitis in the model were compared between fecal microbial microbiome transplantation (FMT), terratin-negative antibiotic de-contamination, and oral or systemic butyric acid dosing in healthy mice.
Pl-8177 was designated by FDA as an orphan drug for the treatment of noninfectious uveitis
Time of Update: 2020-06-19
The disease of noninfective uveitis is characterized by swelling or destruction of the eye tissue, which is not caused by active infection, but by inflammation in the eye According to the position of
Two studies reveal complex communication between the nervous system and the immune system
Time of Update: 2020-06-06
In a new study, researchers from the Feinstein Institute of Medicine in the United States have revealed that the immune system and nervous system are interdependent in their response to any form of va
Green Valley Pharma's new Alzheimer's drug GV-971 gets FDA approval for clinical trials in the U.S
Time of Update: 2020-05-30
Green Valley Pharmaceuticals' controversial new Alzheimer's drug, the Glynette Sodium Capsule (GV-971), has been approved by the FDA for clinical trials in the United States GV971 was approved last
Natural small molecules in the peel can be used to treat myelin damage from multiple sclerosis
Time of Update: 2020-05-30
On April 6, 2020, Zhang Guangxian of Thomas Jefferson University in the United States and Professor Zhang Wei of Shaanxi Normal University collaborated on a research paper entitled A dual effect of ur
Health benefits of curry powder
Time of Update: 2020-04-03
The ingredients of curry powder are actually composed of at least four kinds of spices The most common ingredients are turmeric, cardamom, fennel and coriander They are all spices or herbs with medici
It has been found that microorganisms in the gut may change the aging process of the body
Time of Update: 2019-12-04
Recently, scientists from Nanyang University of technology and other institutions have found that microorganisms living in the gut can change the aging process of the body, which may help researchers