Huntington's "disease modification therapy"! Roche antisense RNA therapy rg6042 (ionis-httrx) was awarded orphan drug qualification in Japan
Time of Update: 2020-02-19
February 19, 2020 / BIOON / -- Chugai, a Japanese pharmaceutical company controlled by Roche, a Swiss pharmaceutical giant, recently announced that MHLW has awarded rg6042
Rogowski antisense RNA therapy rg6042 was awarded orphan drug qualification in Japan
Time of Update: 2020-02-19
Rg6042 (formerly Ionis httrx) is an antisense RNA drug designed to reduce the production of all types of Huntington protein (HTT), including mutant (mhtt), which is the root cause of HD.
The first batch of approved drugs will be donated to the front line of "anti epidemic
Time of Update: 2020-02-17
With the official approval of Haizheng faveravir tablets, Haizheng pharmaceutical will also carry out the registration clinical trials for the treatment of indications of new coronavirus pneumonia, which has been officially approved by the state.
Nature: how does the body realize the mechanical regulation of glycolysis through the cytoskeleton structure
Time of Update: 2020-02-15
This study revealed a new mechanism that glycolysis can react to the cytoskeleton structure of actin, thus promoting the combination of cell metabolism and mechanical properties of surrounding tissues.
Through these changes, cancer cells can transfer and escape from being chased
Time of Update: 2020-02-13
All over the world, cancer is a major threat to human health
One of the most important lethal characteristics of cancer is the ability of cancer cells to spread
It is found that respiratory virus evades the attack mechanism of immune system
Time of Update: 2020-02-13
Researchers at Ohio State University in the United States found that after methylation modification, human partial lung virus successfully reduced the recognition ability of immune protein to virus RNA, thus escaping the attack of immune system.
Roche oral therapy reached the end point of three phases
Time of Update: 2020-02-07
Today, Roche's Genentech company announced that its oral SMN2 gene splicing regulator risdiplam significantly improved the motor function of patients in the critical phase 3 trial of sunfish in the treatment of type 2 or 3 spinal muscular atrophy (SMA).
What does the novel coronavirus epidemic tell us
Time of Update: 2020-01-31
Like SARS and mers, many new diseases are caused by zoonosis, an animal infectious disease, which infects human beings.
[quick news] on January 22, 2020, Ministry of social security: encourage part-time innovation and on-the-job start-up of enterprises by scientific researchers
Time of Update: 2020-01-22
According to Western media, a research report published by the lancet weekly recently shows that influenza can be predicted in real time by measuring heart rate and sleep mode with portable devices.
R & D Daily: AstraZeneca imfinzi combination therapy is qualified to treat liver cancer orphans
Time of Update: 2020-01-21
Imfinzi (durvalumab) and tremelimumab have been awarded the orphan drug qualification for the treatment of HCC by the US FDA, AstraZeneca announced Tuesday.
Nature: identification of a new molecular mechanism of inhibition of host immunity by Mycobacterium tuberculosis
Time of Update: 2020-01-18
Photo source: en.wikipedia.org Mycobacterium Tuberculosis) is a kind of intracellular pathogenic bacteria, which can use many strategies to interfere with the signal transmission function of host immune molecules.
Scientists have found brain circuits linked to eating impulses
Time of Update: 2020-01-13
The researchers identified the hypothalamic to peripheral pathways that regulate impulses, involving communication from the lateral hypothalamic neurons expressed in melanin concentrating hormone (MCH) to the ventral hippocampal subregion (VHP).
Front immune: big data helps design better influenza vaccine
Time of Update: 2019-12-02
December 1, 2019 / BIOON / -- every year, thousands of Americans get sick from flu, thousands of people are hospitalized or die
Influenza vaccination can reduce
Scientists have developed a new method to transport anticancer drugs by nanoparticles
Time of Update: 2019-09-23
Recently, researchers have developed a new method to deliver a class of anticancer drugs ( to cells more completely and accurately using nanoparticles, so as to achieve better anticancer effect, according to a study released by the University of Cambridge.
[quick news] on August 23, 2019, Sanya forum for world top scientists opened, 12 Nobel Prize winners attended
Time of Update: 2019-08-23
The Sanya forum of world top scientists was opened
12 Nobel Prize winners attended the meeting on the morning of August 22
The founding meeting of Sanya forum
[quick news] July 17, 2019 "national excellent self funded overseas student scholarship" project was launched and implemented
Time of Update: 2019-07-17
In 2019, the "national scholarship for outstanding self funded overseas students" project was launched to reward the outstanding academic achievements of self funded overseas
[quick news] the latest natural index on December 17, 2018 shows that China has the most strength in the field of Chemistry
Time of Update: 2018-12-17
In the past five years, scientists have invented sunscreen smart tattoos, and wearable technology has developed rapidly.
Research findings: a new method or cocoa is effective in the treatment of sepsis
Time of Update: 2018-12-08
The researchers of musc showed that the special nano carrier can effectively load and transport miR-126 in the mouse model of sepsis to protect it from RNase damage.
AJP: discovery of new protein can prevent the growth of colon cancer and prolong the survival of patients
Time of Update: 2018-07-18
July 18, 2018 / Biovalley / researchers from Boston University School of Medicine (BUSM) found a new target protein, c-cb1, which they believe will help to further understand colon cancer and ultimately improve the survival rate of patients.
Subcellular localization of key proteins regulates inflammatory response
Time of Update: 2018-02-02
In addition, the level of inflammatory factors produced by arid5a deficient mice was significantly down regulated, and it also had a high tolerance to shock response.