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From ADC to PDC, everything can be coupled
Time of Update: 2022-09-14
ADC drugs are favored by innovative pharmaceutical companies because of their combined therapeutic effects, and PDC (polypeptide conjugated drugs) as a new conjugated drug has also begun to attract a
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Cotton team reveals new mechanism of cotton callus fate regulation
Time of Update: 2022-09-09
Nanhu News (Correspondent Sun Weinan) Recently, the research results of the cotton genetic improvement innovation team of our school were published in The Plant Cell with the title of "GhTCE1-GhTCEE1 dimers regulate transcriptional reprogramming during wound-induced callus formation in cotton" .
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Research and develop a new tool for base editing delivery - virus-like particles can be multi-organ targeted editing
Time of Update: 2022-01-24
11 in the journal Cell, a research team in David Liu's lab at the Broad Institute of MIT and Harvard has developed an engineered DNA-free virus-like particle (eVLP) that can efficiently package and delivery of base editors or Cas9 ribonucleoproteins .
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Alz Res Therapy: Eye tracking task, which can predict emotion recognition disorders in frontotemporal dementia
Time of Update: 2021-12-03
05) ;In a simple emotion recognition task, the average (standard deviation) change score of the stay time in the target area of interest in the control group was 35 (27)%, while the bvFTD group had only 4 (18)% (P<0.
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Nat Cancer: Between brain cancer and tissue repair
Time of Update: 2021-03-11
This suggests that some glioblastomas begin to form during normal tissue healing, a process that produces new cells to replace cells lost to injury, derails due to mutations, and may even disappear many years before the patient develops symptoms.
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Cholesterol into new coronavirus invades cells 'accomplices
Time of Update: 2021-01-29
" cholesterol is a component of the cell membrane that surrounds cells and some viruses, including the new coronavirus, so it is critical for infection.
that if the cell membrane of the new coronavirus lacks cholesterol, the virus cannot enter the target cells.
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Misexpression Approaches for the Manipulation of Flower Development
Time of Update: 2021-01-13
The generation of dominant gain-of-function mutants through activation tagging is a forward genetic approach that complements the screening of loss-of-function mutants and that has been successfully applied to studying the mechanisms of flower development.
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Enter the field of 10 billion anti-fibrosis! Beijing Ted 1 new drug TDI01 approved clinically
Time of Update: 2020-11-11
public information shows that TDI01 is a new target, a new mechanism of oral small molecule drugs, for the highly selective Rho/Rho-related helix formation protein kinase 2 (ROCK2) inhibitors, listed as the country's 13th Five-Year Major New Drug Creations, currently carrying out clinical trials for pulmonary fibrosis, non-alcoholic fatty hepatitis, etc., for the field of first-in-class varieties of the adaptation.
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28 COVID-19 vaccine development competition rankings have won billions of dollars in orders at most
Time of Update: 2020-09-04
4, China Pharmaceutical Group Funding: China Phase 1/2 Clinical: Registered in April Phase 3 Clinical: Starting in July, 15,000 people in Abu Dhabi, the capital of the United Arab Emirates, participating in the national drug candidates are inactivated vaccines, in the Wuhan Institute of Biological Products for its Phase 1/2 trial, the National Pharmaceutical Group said that in the interval of 28 days of two doses of the vaccine patients, 100% of patients showed immune response.
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NK Cell Atlas (II
Time of Update: 2020-07-24
Text Mans immunocheckpoint blocking therapy targeting CD8-T cells is revolutionizing clinical treatment of cancer, and there is growing evidence that NK cells are expected to become the "main force
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Prospects for targeted treatment of glazed cranial pharynx tumors
Time of Update: 2020-05-31
Study background glazed cranial pharynx tumor (adamantinomatous craniopharynoma, ACP) is a type of benign heterogeneous brain tumor formed by rathke's pouch residue in the saddle or saddle area Tumor
