A Novel Chimeric Antigen Receptor T-Cell Approach to Treat Liver Cancer
Time of Update: 2022-09-06
Recently, the research team of Han Zeguang from the Institute of Systems Biomedicine, Shanghai Jiao Tong University published an article titled DLK1-directed chimeric antigen receptor T-cell therapy for hepatocellular carcinoma online in the well-known academic journal Liver International, revealing a novel targeting membrane protein DLK1.
Why does tumor immunotherapy need genetic testing
Time of Update: 2022-09-06
They are single-handed weapons with strong combat effectiveness, and each T cell targets only one type of bad guy; therefore, there are many T cells in the human body, enough to recognize all kinds of tumor cells or foreign viruses .
ACS Nano Harbin Medical University Xu Wanhai/Wang Hao/Wang Lu and others developed a new type of hydrogel that can achieve reversible "ligation" for men
Time of Update: 2022-04-27
On March 30, 2022, Xu Wanhai, Wang Hao, Wang Lu and Qiao Zengying of the National Center for Nanoscience and Technology of Harbin Medical University published a joint communication online at ACS Nano (IF=16) entitled "An Ultrasound-Induced Self-Clearance Hydrogel for Male Reversible" Contraception” research paper in which ultrasound (US)-induced self-clearing hydrogels monitored in real time were used for in situ injection into the vas deferens, enabling effective contraception and non-invasive recanalization when needed .
Hepatology Wenzhou Medical University Huang Zhifeng/Li Xiaokun/Chen Yongping discover new potential therapeutic targets for non-alcoholic fatty liver disease
Time of Update: 2022-03-07
In conclusion, this study identifies FGF4 as a novel stress response regulator of liver pathophysiology that acts through the FGFR4-AMPK-Caspase 6 signaling pathway, revealing novel strategies for the treatment of NAFLD and related liver lesions .
Drugs can simulate fasting, and animal experiments have beneficial results
Time of Update: 2022-02-20
For mice that had become obese on a high-fat, high-sugar diet, the drug treatment caused them to lose weight .
Senior author Brian DeBosch, associate professor of pediatrics, said: "The use of the drug appears to mimic some of the metabolic and therapeutic effects of fasting .
[Internet Rumor Crusher] Stop demonizing pesticides and fertilizers
Time of Update: 2022-02-17
" Academician of the Chinese Academy of Engineering, leader of the scientific fertilization expert guidance group of the Ministry of Agriculture and Rural Affairs, and professor of the School of Resources and Environment, China Agricultural University Zhang Fusuo emphasized that it is necessary to correctly understand the positive effects of chemical fertilizers on agricultural production .
Interview with Professor Li He: Several Key Issues in Lipid Management of Ischemic Stroke CSA & TISC 2021
Time of Update: 2021-08-08
From the perspective of clinical practice, in principle, medication should be used, even if it drops to a normal range, it should be treated, because this is a long-term preventive process, and lipid-lowering drugs can not only reduce the level of low-density lipoprotein cholesterol, it It also protects blood vessels and reduces inflammatory reactions, so as long as there are no side effects, stick to it .
Biomaterials: Progress in research on postoperative treatment and bone repair and regeneration of osteosarcoma
Time of Update: 2021-08-07
Using low-temperature deposition 3D printing technology, a multi-functional porous bionic scaffold containing magnesium-containing biodegradable polymer is developed, which gives it a near-infrared photothermal effect to inhibit tumor recurrence, and sequentially releases magnesium ions to effectively promote bone defect repair .
2021ASCO liver cancer blockbuster study is expected to improve the survival benefits of patients with advanced severe disease, HAIC neoadjuvant shows amazing efficacy 2021ASCO liver cancer special
Time of Update: 2021-06-22
This study of 18 mutant genes showed that patients with advanced high-burden liver cancer with HAIC-FO as the treatment plan were generally better than sorafenib in terms of OS, ORR and safety.
This study explored whether the HAIC-FO regimen neoadjuvant therapy can effectively improve the prognosis beyond Milan Standard liver cancer patients have poor prognosis factors.
Nat Commun: SynNotch CAR-T cells targeting GD2 and B7H3 are expected to treat neuroblastoma
Time of Update: 2021-03-04
Now, in a new study, researchers at Children's Hospital Los Angeles have developed an improved version of car-T cells that show hope in targeting neuroblastoma: killing cancer cells more effectively without harming healthy brain tissue.
Three generic applications for Novarma generic Gilenya have been approved by the FDA
Time of Update: 2021-02-22
Gilenya is understood to have received FDA approval for the first time in 2010 to treat adults with relapsed sclerosis.
In addition, Gilenya may increase the risk of serious infection, so patients need to be monitored for infection during treatment and two months after suspension.
Nature: The psychedelic drug Iberg alkaline similar to TBG is expected to treat addiction and depression without side effects
Time of Update: 2020-12-27
December 14, 2020 /--- In a new study, researchers at the University of California, Davis, have developed a non-hallucinogenic version of the psychedelic drug ibogaine, which has the potential to treat addiction, depression and other mental illnesses.
The Lancet: What's new! The loss of 382 nucleotides may make SARS-CoV-2 infections milder
Time of Update: 2020-10-06
In a study by 2 genome on the severity of infection and the appy response: an observational cohort study, scientists from institutions such as the Singapore Science and Technology Research Agency (A-STAR) found genetic mutations that make the SARS-CoV-2 virus mild.
The gut bacteria are also a natural defense system for our bodies
Time of Update: 2020-09-30
Although the medical community once considered microbes to be feared vectors of disease that should be removed, disinfected and killed with antibiotics, we now know that most of the bacteria in our bodies work in highly complex ways to protect our health and even affect our behavior.
Perts i.m. has filed an application for listing of CAR-T therapy in Japan
Time of Update: 2020-07-17
It is understood that liso-cel was developed by Juno (newly acquired by Juno in January 2018 for $9 billion), which is a CAR-T cell therapy for CD19 antigens with 4-1BB as a co-stimulation zone, in wh