The implications of llamas for antibody discovery
Time of Update: 2022-10-03
Twist Boston has developed and optimized an in vivo method for the discovery of VHH, an antibody produced by the camel family, which enables the rapid identification of VHH antibodies that bind to biological targets on the cell surface and promises to maximize the chances of successful development of these antibodies into therapeutic drugs or diagnostic reagents.
"Broad-spectrum" COVID-19 antibody is authorized by FDA for emergency use to fight infectious diseases, and antibody therapy can be expected in the future
Time of Update: 2021-06-01
Yesterday, the US FDA announced that it granted emergency use authorization (EUA) for the monoclonal antibody therapy sotrovimab jointly developed by Vir Biotechnology and GlaxoSmithKline (GSK) for the treatment of adults and pediatric patients with mild to moderate COVID-19.
Ribozymes: An Introduction
Time of Update: 2020-12-24
One of the more important new insights in the field of molecular biology in the past 15 years was the discovery that RNA molecules, once thought to be primarily passive carriers of genetic information, can carry out some functions previously ascribed to proteins.
MALDI/SELDI Protein Profiling of Serum for the Identification of Cancer Biomarkers
Time of Update: 2020-12-15
The ability to visualize the full depth of the serum proteome in a high-throughput manner is a major goal of clinical proteomics.
Methodologies, which combine higher throughput with the ability to observe differential protein expression levels, have been applied to this goal.
Proteomic Techniques for PlantFungal Interactions
Time of Update: 2020-11-09
More and more pathogen genomes are being sequenced, so fungal proteomics is reaching its full potential and remains the chosen technology to unravel the molecular pathways of pathogenicity and resistance.
In this chapter, we suggest proteomic strategies that have proved successful on various plant-interacting fungal species.
Progress in Parkinson's disease research is at a glance
Time of Update: 2020-10-30
DOI:10.1073/pnas.2003021117 In a recent study published in the international journal Proceedings of the National Academy of Sciences, scientists from institutions such as McLean Hospital found that lipid changes in a class of key brain cells may play a key role in inflammation and Parkinson's disease, and the results are expected to help develop new treatments for Parkinson's disease.
Nat Commun: Scientists are hoping to develop new treatments for malaria
Time of Update: 2020-08-20
image source: Australian National University malaria is caused by the malaria parasite, mainly through the bite of infected mosquitoes to humans, the researchers say, the malaria parasite is evolving to develop some resistance to current drugs, which may be a major threat to effective control and elimination of malaria, in the article, the researchers focused on a protein called PfCRT, which is critical to the generation of malaria parasite strains, but also a potential new drug target.
Can't you translate the protein? It could be that the amino acid sequence is destroying the ribosome
Time of Update: 2017-11-23
background Protein is a three position structure composed of polypeptide chain The amino acid sequence of polypeptide chain is written by DNA code The process of preparing polypeptide chain takes plac
New drug creation project started to apply for benefits of several listed companies
Time of Update: 2014-03-21
2014-03-21 source: on March 19, China Securities Journal, the national health and Family Planning Commission issued a notice to start the application of 2015 major new drug creation In 2015, the proje