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Translational psychiatry: cognitive impairment as a predictor of antidepressant drug targets for major depressive disorder
Time of Update: 2022-11-25
The results showed that the performance of any single cognitive measure at baseline was associated with later clinical response to antidepressant treatment.
the performance of any single cognitive measure at baseline was associated with later clinical response to antidepressant treatment.
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Dig Dis Sci: Safety and efficacy analysis of sedation in patients with upper gastrointestinal bleeding undergoing emergency endoscopic treatment
Time of Update: 2022-11-14
Treatment outcomes and adverse events were assessed using propensity score matching (PSM), and risk factors for UGIB mortality were investigated using Cox multivariate analysis.
Treatment outcomes and adverse events were assessed using propensity score matching (PSM), and risk factors for UGIB mortality were investigated using Cox multivariate analysis.
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The market is very promising and is constantly ushering in blockbuster financing
Time of Update: 2022-11-11
In February, Jingyu Medical announced the completion of a RMB D+ round of financing of RMB 300 million, co-led by Sequoia China and Hillhouse Venture Capital.
In February, Jingyu Medical announced the completion of a RMB D+ round of financing of RMB 300 million, co-led by Sequoia China and Hillhouse Venture Capital.
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ESMO Pre-"Research" Newsletter Radioactive Ligand Therapy in mCRPC
Time of Update: 2022-09-21
This study aimed to evaluate the safety and efficacy of treatment with 177 patients with metastatic castration-resistant prostate cancer (mCRPC) in the RALU study after using 233Ra with 177Lu-PSMA.
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At the beginning of September, a large number of enterprises in the pharmaceutical field received tens of millions of yuan in financing
Time of Update: 2022-09-07
This round of financing is led exclusively by Juming Venture Capital, and the old shareholder Kaifeng Venture Capital continues to invest, and the funds raised will be mainly used for the research and development, product registration and clinical declaration of existing new targets and new product pipelines.
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Sartorius Acquires Albumedix, Innovative Products Enable Advanced Therapies
Time of Update: 2022-08-20
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Sci Rep: Hydrogen gas from silicon-based absorbable formulation may reduce inflammation in patients with ulcerative colitis
Time of Update: 2022-08-16
ulcerative colitisulcerative colitisRecently, in a research report titled "A new therapy against ulcerative colitis via the intestine and brain using the Si-based agent" published in the international journal Scientific Reports , scientists from Osaka University and other institutions passedThe study designed an absorbable formulation that may target the high-level oxidative mechanisms associated with ulcerative colitis in laboratory mouse models .
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Eli Lilly's third COVID-19 neutralizing antibody receives FDA emergency use authorization for Omicron
Time of Update: 2022-05-29
Recently, Eli Lilly announced that its new crown neutralizing antibody bebtelovimab has been granted Emergency Use Authorization (EUA) by the FDA for the treatment of patients with mild to moderate new coronary pneumonia .
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The new indication of WuXi Junuo CAR-T therapy for the treatment of follicular lymphoma is planned to be included in priority review
Time of Update: 2022-04-29
Diseases caused by mutations in B cells and their precursor cells, and most tumor cells also express CD19, making CD19 a popular target for new drug development .
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Nature sub-journal: This method can shorten the culture time of CAR T cells
Time of Update: 2022-04-22
"While traditional manufacturing methods for making CAR-T cells take days to weeks, there is still a need to reduce the time and cost of producing these complex therapies," Milone said.
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Radiology: Diagnostic value of synthetic FLAIR sequences in acute ischemic stroke
Time of Update: 2022-04-22
(C) 86-year-old female , a sudden onset of right hemiparesis at 5 hours and 10 minutes prior to MRI , with no DWI-FLAIR mismatch on synthetic FLAIR and real FLAIR images .
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To solve "non-drugable" and "resistance", Nature summarizes the four major trends in the development of PROTAC
Time of Update: 2022-03-08
The authors propose that the next milestones in the PROTAC field will focus on the following four areas, namely, identifying the best protein degradation targets; expanding the scope of clinical application of E3 ligases; expanding the scope of clinical treatment to diseases beyond oncology; Develop other PROTAC modes .
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JAMA sub-issue: Whether metformin can "assist" lung cancer treatment, the key may be this indicator
Time of Update: 2022-02-20
The trial included patients with EGFR mutation-positive non-small cell lung cancer (NSCLC) and randomly assigned to receive EGFR-TKIs alone or the combination of EGFR-TKIs and metformin (500 mg twice daily) .
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Gut: How effective is H. pylori eradication therapy in functional dyspepsia
Time of Update: 2022-02-17
pylori eradication therapy is beneficial, but since then a number of randomized controlled trials (RCTs) have been published .
pylori eradication therapy on FD cure and improvement, and whether H.
Helicobacter pylori eradication therapy was associated with improved (RR=0.
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The latest development of ADA-SCID gene therapy in 90% of children with continued health after ten years of treatment
Time of Update: 2021-12-04
A few days ago, researchers at the University of California, Los Angeles reported on "Blood" related data on experimental gene therapy for severe combined immunodeficiency (ADA-SCID) children.
