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Diabetic hyperglycemia promotes primary tumor progression through glycation-induced extracellular stromal sclerosis
Time of Update: 2023-01-05
Inhibition of FAK-mediated cellular mechanical sensing slows the progression of diabetic tumors without affecting ECM stiffnessTo confirm that glycosylation promotes tumor progression by strengthening the tumor extracellular matrix (ECM), which in turn activates cellular mechanical sensing signals, STZ-injected mice were treated with the adhesion kinase (FAK) inhibitor PF573228 for 7 weeks until the end of the study.
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J Clin Oncol: Cancer patients who actively self-monitor have a relatively better prognosis
Time of Update: 2022-10-19
Patients who completed the overall MWC questionnaire had a much lower risk of emergency department visits (adjusted hazard ratio = 0.
Patients who completed the overall MWC questionnaire had a much lower risk of emergency department visits (adjusted hazard ratio = 0.
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Italy: Before the Wuhan outbreak, the new crown had spread around the world! The explosion of measles cases hides the truth
Time of Update: 2022-09-15
Looking back at the case of skin diseases in the pre-COVID-19 outbreak, Italian scientists have reassessed the association between COVID-19 infection and measles-like syndrome, providing preliminary evidence for the undetected early spread of the new coronavirus.
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food additive nitrogen
Time of Update: 2022-08-19
Table 2 Physical and chemical indicatorsRelated Links: Food Additive Ammonia Test Method (2)Food additive ammonia water test method (2) 1 ScopeThis standard applies to nitrogen production by cryogenic air separation, nitrogen production by pressure swing adsorption, nitrogen production by membrane separation, and food additive nitrogen produced by small special nitrogen generators .
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Keji Pharmaceutical's solid tumor CAR-T product candidate CT041 entered a confirmatory phase II clinical trial in China
Time of Update: 2022-05-01
HK), an innovative CAR-T focused on the treatment of hematological malignancies and solid tumors The cell therapy company announced today that its self-developed CAR-T cell candidate product CT041 has been approved by the China National Medical Products Administration (NMPA) Center for Drug Evaluation (CDE) to enter a confirmatory phase II clinical trial.
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Cell Rep: Discovery of a new pathway for DNA transfer in the tumor microenvironment
Time of Update: 2022-04-25
"We've shown that DNA is present in these microvesicles with transference, and now we have an excellent platform to assess genetic aberrations," said D'Souza-Schorey, who is also affiliated with the Berthiaume Institute for Precision Health, Boler-Parseghian Center for Rare and Neglected Diseases and Harper Cancer Institute .
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J Hematol Oncol: Serological responses to SARS-COV2 vaccine in cancer patients
Time of Update: 2022-04-19
Recent studies have reported that patients with hematological malignancies, especially those receiving anti-CD20 therapy or with a history of stem cell transplantation, are less immunogenic against BNT162b2 or mRNA1273 SARS-CoV-2 vaccines compared with patients with solid tumors .
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How is primary osteoporosis diagnosed and treated
Time of Update: 2022-03-07
*For reference only for medical professionals Osteoporosis is also known as the "silent killer", because most patients have no obvious clinical symptoms at the onset of the disease, which brings difficulties to the early detection and diagnosis of the disease; when patients experience bone pain, body shape changes or even fractures , often too late .
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The details of the Phase 3 study of K medicine + Lenva's failure are released
Time of Update: 2022-01-11
Following KN189, is the new immunotherapy combination therapy expected to redefine the ceiling of the first-line treatment of NSCLC?LEAP-007: Coke combination ushered in the first failure of Phase III studyLEAP-007: Coke combination ushered in the first failure of Phase III studyIn the past, in phase Ib/II, open-label, one-arm trials (study code 111/KEYNOTE-146, NCT02501096), drug K + lenvatinib showed encouraging results in patients with metastatic NSCLC (n=21) Anti-tumor activity (ORR 33%, median PFS 5.
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Researchers report the reliability of Pfizer's new crown vaccine trial data, and the effectiveness of FDA clinical supervision is questioned
Time of Update: 2021-11-14
The article reported an internal whistleblower's revelation of the bad practices of the contract research company that helped conduct Pfizer's key new crown vaccine trial , Which has raised concerns about the reliability of data and the effectiveness of FDA supervision .
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"Online" Ya'an, where can I still find someone to take the driver's license test "Mobile Sohu" oh
Time of Update: 2021-11-03
" Zhou Ying thinks that the current software's prompts are good, but for users Said that it is necessary to strengthen the awareness of personal protection, “Some young users may be full of curiosity about the society and want to experience the feeling of meeting netizens /> He is just a bald head with a hat, optimistic and sunny, no different from ordinary people.
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New cancer treatments may wake up the immune system
Time of Update: 2021-11-03
Researchers at the Massachusetts Institute of Technology have now discovered a new way to activate the immune system to attack tumors, which they hope will allow immunotherapy to treat more types of cancer .
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The treatment of cholangiocarcinoma welcomes new FGFR inhibitors, and currently three types of FGFR inhibitors have been approved
Time of Update: 2021-10-23
3. Infigratinib, an innovative, oral, FGFR-1, 2, 3 selective and potent inhibitor, was approved by the FDA in May 2021 for the treatment of previously treated locally advanced patients with FGFR2 fusion or rearrangement Or patients with metastatic cholangiocarcinoma .
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Combination immunotherapy may help lung cancer patients activate anti-tumor responses
Time of Update: 2021-08-26
The latest international research: combined immunotherapy may help lung cancer patients activate anti-tumor response The latest international research: Combination immunotherapy may
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How to deal with peeling after sunburn: this is the only thing you can’t do
Time of Update: 2021-08-07
Curcio recommends continuing to moisturize, protect and cover your skin, and help it heal faster .
"Exfoliation burns are healing, so please continue to use SPF 30 or higher sunscreen to protect your skin as much as possible from the sun and avoid further burns .
