Professor Wu Depei on World AML Day: Interpreting the New Trend of R/R AML in Precision Targeted Therapy
Time of Update: 2022-06-12
Acute myeloid leukemia (AML) is the most common type of leukemia in adults and has historically had a high mortality rate . With the deepening of medical research, the treatment of AML has develop
"The Lancet" sub-issue: Not better than chemotherapy, ADC drugs challenge malignant pleural mesothelioma and get negative results; T-DXd is planned to be included in breakthrough therapy in China
Time of Update: 2022-04-27
Screenshot from journal website This randomized, open-label, phase II study at 76 hospitals in 14 countries enrolled adults (age ≥18 years) with unresectable locally advanced or metastatic malignant pleural mesothelioma, Eastern United States Patients with a Cooperative Oncology Group (ECOG) performance status score of 0-1 and who had disease progression after first-line platinum-based + pemetrexed chemotherapy (with or without bevacizumab) .
This new drug has a disease control rate of up to 100% for pancreatic cancer; natural killer cell therapy is expected to be the first-line treatment for advanced gastric cancer
Time of Update: 2022-02-20
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Biopharmaceutical companies join hands with new R&D institutions: to promote the transformation of hematopoietic stem cell regeneration therapy
Time of Update: 2022-02-19
In 2021, Boya Jiyin initiated a phase I multicenter clinical trial of ET-01, the first gene-edited hematopoietic stem cell therapy research product for transfusion-dependent β-thalassemia in China, and was conducted in the Hematology Hospital of the Chinese Academy of Medical Sciences (Chinese Academy of Medical Sciences).
How bacterial defenses affect the spread of 'mobile genetic elements
Time of Update: 2022-01-22
"The MUSIC project aims to understand how the bacterial immune system keeps mge out," said Dr Van Houte, from the Institute for Environment and Sustainability at Penryn Campus, Exeter, Cornwall .
Why do people sleep
Time of Update: 2021-12-01
According to a new study published in "Molecular Cell" on November 18, researchers from Bar-Ilan University in Israel found that the PARP1 protein in the brain is like an "antenna" that can send time signals to the brain to sleep and repair DNA damage.
[Nature Magazine] Childhood liver cancer is caused by epigenetic mutations, and its origin is just a hepatoblast
Time of Update: 2021-10-01
Researchers at Hiroshima University analyzed molecular studies of nearly 160 cases of childhood liver cancer, and discovered molecular markers that help understand and treat huge differences in prognosis .
Cell sub-news "bypass" aging: stay young, start with cells
Time of Update: 2021-10-01
Researchers at Université de Montréal and McGill University have discovered a new multi-enzyme complex that can reprogram the metabolic program to overcome "cell senescence", that is, aging cells stop dividing .
Science: "Noisy" gene expression plays a key role in development
Time of Update: 2021-09-19
While studying HIV, Weinberger's team discovered the existence of some molecules that can increase noise or switch the expression mechanism between active and inactive states, but strangely, they do not affect the average expression level .
"Hobbit" turns immune cells into killers
Time of Update: 2021-09-13
"We want to understand how immature ILCs become effector cells, for example, to kill tumor cells or fight infections with the help of cytokines," Professor Georg Gasteiger, Chairman and Head of the Max Planck Research Group of the JMU Institute of Systemic Immunology Explained .
Chemotherapy can destroy the gut health of cancer patients
Time of Update: 2021-08-05
Lito Papanicolas, an infectious disease expert and clinical microbiologist from SAHMRI and Flinders University in South AustraliaSource: South African Institute of Health and Medical Research (SAHMRI)New research on BMC cancer shows that myelosuppressive chemotherapy destabilizes the gut microbiota of patients with solid organ cancers .
Mol Cell: Scientists have discovered special proteins that can induce certain cancerous tumors
Time of Update: 2021-06-22
Recently, in a research report entitled "XRCC1 prevents toxic PARP1 trapping during DNA base excision repair" published in the international journal Molecular Cell , scientists from the University of Sussex and other institutions have dug into the body’s DNA damage through research.
What are the research progress of Behcet's disease
Time of Update: 2021-04-23
In 2020, a study published by Professor Wenjie Zheng on clin immunol showed that monocytes in patients with BD have an imbalance of Fcy receptor (Ig Fc fragment binding receptor), and this imbalance is related to disease activity.
National Key Laboratory of Neuroscience: They Have "Everybody" in Their Hearts
Time of Update: 2021-02-24
sterilization work Qin Zhiwei photo staff in cleaning monkeys "home" neuroscience national key laboratory for illustration just out of the rat room staff, clothes have been wet Qin Zhiwei
Cell: Reveals that cytokine storms prevent patients with neocyto pneumonia from developing long-lasting immune responses
Time of Update: 2020-09-29
"When we looked at the lymph nodes and spleen of patients who died of COVID-19 --- including some who died shortly after getting sick--- we saw that these birth center structures had not yet formed," said co-author of the paper, Professor Robert Padera of Bregan Women's Hospital.