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Rheumatology: rheumatoid arthritis macrophages respond to inflammation and exhibit changes in bioenergetic and functional
Time of Update: 2023-01-04
unique inflammatory and metabolic phenotype of RA monocytes-derived macrophages and identifies the key roles of NAMPT and STAT3 signaling in regulating this phenotype Sources:Sources:Hanlon MM, McGarry T, Marzaioli V, et al.
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New York copper volatility fell slightly, and the short-term rally came to an end
Time of Update: 2022-11-30
Copper periodCopper prices fell nearly 3 percent in the cycle as the dollar slipped after the Federal Reserve lowered its forecast for the number of rate hikes in 2016.
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Molecular Cell: A novel mechanism by which cytosolic histone deacetylase SIRT6 promotes fatty acid oxidation
Time of Update: 2022-10-20
One of the most common chronic liver diseases is nonalcoholic fatty liver disease (NAFLD), which includes simple fatty liver disease and nonalcoholic steatohepatitis (NASH), a more serious metabolic
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The conscious perception of sound consists of specialized neurons in the brain
Time of Update: 2022-10-20
When the brain perceives auditory stimuli under anesthesia, a collection of hundreds of neurons also appears, but only in the awake and conscious state do specific neurons appear and are associated with specific sounds.
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Application of midbrain dopamine in neuronal circuits regulating humoral balance
Time of Update: 2022-08-30
For more information, please contact Tel: +86-0731-84428665 Contact: Manager Wu +86-180 7516 6076 Water and food have rewarding properties, primarily because they satisfy the body's intrinsic needs .
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JAMA Netw Open: Stop-and-go elderly with slow gait reduces risk of cognitive impairment
Time of Update: 2022-01-22
recently published research in the journal JAMA Netw Open evaluating whether low activity fragmentation in older adults with slow gait is a neural cause of slow walking, putting these individuals at higher risk for AD .
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Real model of mouse hippocampus reveals new mechanism of pattern separation
Time of Update: 2021-12-26
There are 500,000 neurons in a modelIn previous studies, Jonas and his team measured the key parameters of synapses, neuronal connections, and connection rules that are necessary to understand information processing in the hippocampal networks of mice and rats .
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"Pig Boss" Muyuan shares can not escape losses, slowing down expansion and reducing costs
Time of Update: 2021-11-13
”Large-scale expansion puts capital under pressure Industry insiders pointed out that in addition to the impact of the epidemic, the increase in feed costs, and the decline in pig prices, the previous large-scale expansion of pig companies such as Muyuan shares during the pig dividend period has also put their costs and funds under short-term pressure during the current trough of the pig cycle .
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Hepatocyte mutations associated with liver disease and fat metabolism
Time of Update: 2021-11-04
In addition, although more research is needed, this research may lead to a potential new model to understand how mutations in specific cell types can lead to systemic metabolic diseases, such as diabetes .
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OMCL: The renal protection induced by aerobic exercise in obese Zucker rats depends on the bioavailability of nitric oxide
Time of Update: 2021-10-20
Since AT is an important inducer of nitric oxide (NO-) that mediates kidney health phenotypes, this study aims to investigate the effects of AT on metabolic parameters, morphology, redox balance, inflammation spectrum, and obesity-diabetic Zucker rats Changes of renal vasoactive peptides after receiving L-NAME (N(omega)-nitro-l-arginine methyl ester) .
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In Vivo NMR for 13C metabolic Flux Analysis
Time of Update: 2021-01-18
In vivo NMR allows to visualize the active metabolic network, to determine metabolic and isotopic steady state and to measure metabolic fluxes which are not necessarily accessible by isotopic steady state (stationary) Metabolic Flux Analysis.
The kinetic data can be used as input for dynamic (nonstationary) Metabolic Flux Analysis.
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The metabolic inhibition model which predicts the intestinal absorbability and Metabolizability of drug: Theory and experiment
Time of Update: 2020-11-27
The intestinal absorption of analgesic peptides (leucine enkephalin and kyotorphin) and modified peptides in rat were studied.
This model predicted the maximum absorption clearances of cellobiose-coupled leucine enkephalin (0.654 �l/min/cm) and kyotorphin (0.247 �l/min/cm).
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Lancet: Can coronavirus cause diabetes
Time of Update: 2020-09-30
study found that insulin-producing cells were destroyed by the virus in some people with neo-coronary pneumonia.
latest clue comes from a study of laboratory pancreatic organs published last week that suggests the virus could cause diabetes by destroying cells that control blood sugar.
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Gastroenterology: An unexpected discovery in hyper-expanded endoscopy monitoring ulcerative colitis. Case studies
Time of Update: 2020-07-19
therefore, folic acid may have chemopreventive effect on colorectal cancer and can be used as a preventive drug for uc-crc.
analysis of risk factors of ulcerative colitis related colorectal cancer [J].
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Everyone! 2020 China CRO company list hot registration
Time of Update: 2020-07-19
Guide: Research and development CRO and CDMO company hasten to register! June 23rd, the "2020 China CRO Company Rankings" competition launched by the Organizing Committee of the China Pharmaceutical
