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Grace

Sitafloxacin (Trade name: Gracevit in Japan) belongs to a new generation, broad-spectrum oral fluoroquinolone antibiotics. It is highly active against various kinds of gram-negative, gram-positive and anaerobic clinical isolates, even including strains that are resistant to other kinds of fluoroquinolone antibiotics. It has been listed in Japan for the treatment of respiratory and urinary tract infections. It also shows potential for the treatment of Buruli ulcer. Its mechanism of action is thr

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US Coast Guard Intercepts Ship Carrying Fuel to Cuba

The US Coast Guard intercepted the cargo vessel 'Grace' in the Caribbean, confirming it carried fuel bound for Cuba amidst ongoing US oil embargoes and sanctions.

reuters · 2026-10-02 06:41

Product Info

Name (EN)	Sitafloxacin
CAS No.	127254-12-0
Molecular Formula	C19H18ClF2N3O3
Type	product
Application	Antibacterial (DNA-gyrase inhibitor).A group 4 quinolone formulated for oral or intravenous use. In-vitro activity is similar to or better than that of moxifloxacin. The antibacterial spectrum covers Gram-positive and Gram-negative bacteria including anaerobes. It has a chlorine atom at the C-8 posi
Other Names (EN)	3-Quinolinecarboxylic acid,7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-;3-Quinolinecarboxylic acid,7-(7-amino-5-azaspiro[2.4]hept-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-,[1R-[1α(S*),2α]]-;5-Azaspiro[2.4]hept
Description	Sitafloxacin (Trade name: Gracevit in Japan) belongs to a new generation, broad-spectrum oral fluoroquinolone antibiotics. It is highly active against various kinds of gram-negative, gram-positive and anaerobic clinical isolates, even including strains that are resistant to other kinds of fluoroquin