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Endocrine System

Diabetes Care: A global epidemiological analysis of end-stage kidney disease associated with diabetes

 Time of Update: 2020-11-26

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a recent study published in Diabetes Care, an authoritative journal in the field of diabetes, aims to compare the incidence of diabetes-related ESRD by creating a global atlas from 2000 to 2015.
JAMA:omega-3 fatty acids had no significant clinical benefits for high-risk cardiovascular patients who were receiving statin therapy

 Time of Update: 2020-11-26

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in 22 countries in North America, Europe, South America, Asia, Australia, New Zealand and South Africa, and the researchers looked at the high cardiovascular risk, high triglycerideemia and HDL cholesterol (HD) L-C) low-level population effects
Metabolism: MAFLD and CKD Risk

 Time of Update: 2020-11-26

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, the prevalence of CKD was higher in MAFLD patients than in NAFLD, which is associated with non-metabolic dysfunction.
JCEM: Bone metabolism in adolescents undergoing bariatric surgery

 Time of Update: 2020-11-26

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result, adolescent MBS was associated with aBMD reduction and an increase in MATT in axial bones, while a sleeve gastric excision was associated with an increase in cortique vBMD and a decrease in MAT in surrounding bones.
Diabetes Care: Relationship between severe hypoglycemia and heart structure and function and cardiovascular event risk in older diabetics

 Time of Update: 2020-11-26

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A recent study published in Diabetes Care, an authoritative journal in the field of diabetes, aims to assess the link between severe hypoglycemia and cardiovascular disease (CVD) measured at baseline in older diabetics living in the community.
Less re-evidence! Pay attention to the new ideas of Zinlida particles to prevent and control metabolic diseases such as obesity and type 2 diabetes

 Time of Update: 2020-11-26

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, a randomized, double-blind, placebo-controlled study conducted by academician Yu Xiaolin also showed that the use of Zinlida particles combined with metformin was effective in reducing sugar and controlling symptoms, while also effectively reducing
NEJM: Golimumab partially restores islet function in young people with new type 1 diabetes

 Time of Update: 2020-11-26

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study, Golimumab therapy can improve endogen insulin production and reduce the use of extrogenic insulin in people with type 1 diabetes.
JAMA Pediatrics: Weight worries and dieting are on the rise among teens, or lead to depression

 Time of Update: 2020-11-26

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since the 1960s and 1970s. Dr Solmi, lead author of the study, said: "The media's description of slim figures, the rise of the fitness industry and the emergence of social media may partly explain our findings, and public health information
Diabetes Care: The association between pre-pregnancy diabetes and gestational diabetes in pregnant women and congenital malformations in newborns

 Time of Update: 2020-11-06

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it can be seen that pre-pregnancy diabetes and GDM are associated with several subtypes of congenital abnormalities in newborns.
JCEM: Analysis of vitamin D status in coVID-19 hospitalized patients

 Time of Update: 2020-11-05

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/> 19 of the 216 patients were treated with vitamin D supplements and analyzed separately. in patients with COVID-19, the average ±SD level of 25OHD was 13.8±7.2 ng/ml, compared with 20.9±7.4 ng/ml in the control group. 25OHD in men
LDL-C < 1.4 mmol/L, ≥ 50% reduction! Consensus among experts on clinical pathways for ACS lipid management in the Chinese Physicians Association

 Time of Update: 2020-11-05

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the consensus recommendation of acute coronary syndrome combined with high-risk factors, similar to those in the ultra-high-risk group recommended by experts on reducing cardiovascular events in the Chinese Cholesterol Education Program.
BMJ: Hormone replacement therapy type and duration associated with breast cancer risk

 Time of Update: 2020-11-05

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recently assessed breast cancer risk associated with different types and duration of hormone replacement therapy (HRT).
Finerenone significantly reduces kidney and cardiovascular events in adults with chronic kidney disease and type 2 diabetes

 Time of Update: 2020-11-05

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and type 2 diabetes compared to placebo. , Finerenone significantly reduced the risk of major compound endpoints by 18% (relative risk reduction, HR 0.82 (95% CI, 0.73-0.93; p-0.0014), the main composite endpoints include the occurrence of kidney
Lancet: Effects of postoperative radiotherapy strategies on PSA processes for prostate cancer

 Time of Update: 2020-11-05

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RADICALS-RT study, patients with at least one biochemical progression risk factor (pathological stage 3 or 4, Gleason scored 7-10, positive edge, or preoperative PSA ≥10 ng/mL) after a root-and-treated prostatectomy were recruited.
JCEM: Weight gain after thyroidectomy

 Time of Update: 2020-11-05

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study follow-up, gender, and age, the researchers analyzed metagression models of single-variable and multivariable weight changes, and performed exploratory subgroup analysis of surgical fingering.
The world's third RNAi therapy, lumasiran, is about to be approved to treat a rare liver disease, type 1 primary high herbic aciduria

 Time of Update: 2020-11-05

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recently, a third RNAi drug, oxlumo®, was approved to treat the rare genetic liver disease type 1 primary high oxalic aciduria (PH1), which was recently supported by a number of positive data.
Bayer buys gene therapy company AskBio for $4 billion

 Time of Update: 2020-11-05

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AskBio's adeno-related gene (AAV) treatment platform has shown potential in a variety of diseases, and the company's main research program focuses on Pompeia, Parkinson's disease and congestive heart failure.
JCEM: Serum serotonin as a new predictor of brittle fractures

 Time of Update: 2020-11-05

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result, an increase in baseline subsemination concentration was associated with a risk of osteoporosis fractures during an average of 9 years of follow-up.
NEJM: Zinc deficiency related dermatitis - case reported

 Time of Update: 2020-11-05

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zinc deficiency is relatively easy to treat and needs to be considered for the identification and diagnosis of refractic specialty dermatitis, pustules and other eczema skin diseases.
JCEM: Relationship between hair cortisol concentration and fat in children

 Time of Update: 2020-11-04

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Starting in childhood, stress can lead to poor body fat distribution. , a study published recently in Journal of Clinical Endocrinology and Metabolism, an authoritative journal in the field of endocrine and metabolic diseases, aims to assess

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Endocrine System

Diabetes Care: A global epidemiological analysis of end-stage kidney disease associated with diabetes

JAMA:omega-3 fatty acids had no significant clinical benefits for high-risk cardiovascular patients who were receiving statin therapy

Metabolism: MAFLD and CKD Risk

JCEM: Bone metabolism in adolescents undergoing bariatric surgery

Diabetes Care: Relationship between severe hypoglycemia and heart structure and function and cardiovascular event risk in older diabetics

Less re-evidence! Pay attention to the new ideas of Zinlida particles to prevent and control metabolic diseases such as obesity and type 2 diabetes

NEJM: Golimumab partially restores islet function in young people with new type 1 diabetes

JAMA Pediatrics: Weight worries and dieting are on the rise among teens, or lead to depression

Diabetes Care: The association between pre-pregnancy diabetes and gestational diabetes in pregnant women and congenital malformations in newborns

JCEM: Analysis of vitamin D status in coVID-19 hospitalized patients

LDL-C < 1.4 mmol/L, ≥ 50% reduction! Consensus among experts on clinical pathways for ACS lipid management in the Chinese Physicians Association

BMJ: Hormone replacement therapy type and duration associated with breast cancer risk

Finerenone significantly reduces kidney and cardiovascular events in adults with chronic kidney disease and type 2 diabetes

Lancet: Effects of postoperative radiotherapy strategies on PSA processes for prostate cancer

JCEM: Weight gain after thyroidectomy

The world's third RNAi therapy, lumasiran, is about to be approved to treat a rare liver disease, type 1 primary high herbic aciduria

Bayer buys gene therapy company AskBio for $4 billion

JCEM: Serum serotonin as a new predictor of brittle fractures

NEJM: Zinc deficiency related dermatitis - case reported

JCEM: Relationship between hair cortisol concentration and fat in children