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Drugs Articles

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Ruike Biotechnology completes nearly RMB 1 billion in Series C financing

 Time of Update: 2021-06-22

> . > Ruike Biotechnology was formed by the merger of Jiangsu Ruike Biotechnology Co. , Ltd. and Beijing Anbaisheng Biotechnology Co. , Ltd. , focusing
FDA approves Biogen's new drug for Alzheimer's disease, provokes public outrage and 3 panelists resign

 Time of Update: 2021-06-22

When the world boiled over when Biogen's new Alzheimer's drug Aduhelm was approved by the US Food and Drug Administration (FDA) for marketing, the three experts on the FDA's Expert Advisory Committee left their posts "angry" .
Merck Keytruda was approved for the 7th indication in China, the first-line treatment of colorectal cancer!

 Time of Update: 2021-06-22

> . The approval of the new indication for pembrolizumab is based on data from the key global phase 3 clinical trial KEYNOTE-177 . </span
Guidelines for patient reporting outcomes in FDA cancer trials, measuring five core concepts

 Time of Update: 2021-06-22

standardize the evaluation of patient reported outcomes (PRO) in cancer drug registration trials. The guidelines recommend that sponsors collect five core types of PRO data . ><span
The full text is here!

 Time of Update: 2021-06-22

Committee on June 10. It has eight chapters and 57 articles, covering trade freedom and convenience, investment freedom and convenience, and fiscal taxation. The core points and full text of the system, ecological environment
The FDA is disappointed with the slow progress in the application of stem cell therapy and will strengthen law enforcement against the sale of unapproved products

 Time of Update: 2021-06-22

[FDA announced a comprehensive regenerative medicine policy framework 2017/11/18] Bryan said that for the manufacturers of these products, the period of law enforcement discretion is now over .
Guocai "Renewal Season": "Shanghai Plan" is here!

 Time of Update: 2021-06-22

categories> > 01 Formation of a price mechanism guided by centralized drug procurement >01 Formation of a price mechanism guided by centralized drug procurement
Merck launches two new anti-HIV drugs, Destro and Pedro in China

 Time of Update: 2021-06-22

Desi Zhuo ® and Peizhuo ® respectively in January 2021 and November 2020, the Chinese State Drug Administration approval for the treatment of adult HIV-1 virus infection .
Zejing Pharmaceutical's JAK inhibitor phase 2 clinical success

 Time of Update: 2021-06-22

On June 11, Zejing Pharmaceutical issued an announcement stating that its Phase 2 clinical study (ZGJAK002) for the treatment of intermediate and high-risk myelofibrosis with its new
Are the suddenly popular digital therapies and digital medicines really reliable...

 Time of Update: 2021-06-22

/>. Luo Xiaobin said that MyoHealth’s advantage is that “our digital therapy products have been organically combined with commercial insurance, and a clearer payer has been found, which proves its actual effectiveness

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Feed Industry News

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A total of 4562 dead wild birds have been found!

 Time of Update: 2021-06-22

a report of unexplained deaths of wild birds on the banks of Hongjiannao Lake, the local government immediately followed the procedures to report to the higher authorities, and it started in due course. In response to the emergency response plan
The "anti-resistance order" is officially implemented, and the cost of breeding will rise across the board

 Time of Update: 2021-06-22

technological progress, improve the level of breeding management, strengthen biosafety measures, promote the standardization, scale, industrialization, and modernization of the breeding industry, promote the transformation and upgrading
Strange thing!

 Time of Update: 2021-06-22

wheat cutting machine" has been developed, it can solve the "wheat cutting pollution" from a technical level . Under this premise, it is understandable to encourage farmers to use more advanced
The price of pork is almost cut in half!

 Time of Update: 2021-06-21

　　On June 9th, May price data was announced. The National Consumer Price Index (CPI) rose by 1. 3% year-on-year, which was slightly lower than market
The number of imported corn in the second auction has doubled, the price of live pigs hit a record low, and a three-level warning for pig prices has been issued.

 Time of Update: 2021-06-21

>Zqs China Feed Industry Information Network-Based on feed, serving animal husbandry>　　Affected by news that the US planting weather improved crop yields and the US may cut the biodiesel blending rate, CBOT corn
From "lying to win" to "blood loss", pig futures have been diving for days

 Time of Update: 2021-06-21

2% month-on-month in the first half of the months6d China Feed Industry Information Network-Based on feed, serving animal husbandry　　Entering June, the national live pig price decline continued to expand .
The price of live pigs hits a record low, the sales of head pig companies are differentiated

 Time of Update: 2021-06-21

> . hXz China Feed Industry Information Network-Based on feed, serving animal husbandry>　　The weakness of pig prices is also reflected in the sales data
Gathering is a group of fire scattered and made of gypsophila-2021 Sino-German youth agriculture practical

 Time of Update: 2021-06-21

summer, a group of special guests were welcomed in Qingqing Ranch in Mawang Village, Huaqiao Town, Xinjin County, Chengdu City, Sichuan Province . The 2021 Sino-German Youth was organized
Shandong has released a three-year action plan, and 49 hazardous chemical production companies have completed their relocation and transformation this year!

 Time of Update: 2021-06-19

Zhang Xiaohai, Deputy Director Zhou Fengwen of the Provincial Emergency Management Department, and Deputy Chief Dong Xinming of the Provincial Fire Rescue Corps introduced the three-year action plan for the special rectification of production safety
The global supply chain crisis has intensified!

 Time of Update: 2021-06-17

qQB China Feed Industry Information Network-Based on feed, serving animal husbandry　　Among them, the total import of poultry meat in April was 120,000 tons, a decrease of 9.

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Antitumor Therapy

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B7-H3 ADC clinical data released:

 Time of Update: 2021-06-23

At the 2021 ASCO annual meeting, the biopharmaceutical company MacroGenics announced the preliminary safety and anti-tumor activity data of the ongoing phase I dose-escalation clinical trial of MGC018 (NCT03729596) .
Inventory of the domestic Class 1 NDA applications undertaken by CDE for the first time from January to May 2021...

 Time of Update: 2021-06-23

A multi-center, open, single-arm Phase II clinical study evaluating the efficacy of the drug in locally advanced or metastatic NSCLC patients who have developed resistance after first-generation or second-generation EGFR-TKI treatment and are positive for EGFR-T790M mutations And safety .
GlaxoSmithKline PD-1 inhibitor Jemperli...

 Time of Update: 2021-06-23

Jemperli is a PD-1 blocking antibody, specifically suitable for: recurrence of disease progression, mismatch repair defect (dMMR)/high degree of microsatellite instability (MSI-H) during or after treatment with platinum-containing chemotherapy Patients with sexual or advanced endometrial cancer .
Innomicropharmaceuticals MVR-T3011 (intratumor injection) clinical phase II first case of drug delivery completed simultaneously in China and the United States

 Time of Update: 2021-06-22

Innomicropharmaceuticals announced that its leading oncolytic virus product MVR-T3011 intratumoral injection (MVR-T3011 IT) phase II clinical study will be completed on May 28 and June 11, 2021, in China and the United States, respectively.
Using machine learning algorithms to predict the recurrence of stage IV colorectal cancer after surgery

 Time of Update: 2021-06-22

734, this model can still predict cancer recurrence; however, the gbm algorithm model has the highest AUC value (0.
To see the future, gynecological tumor treatment ushered in a "window of opportunity" 2021 ASCO gynecological tumor special

 Time of Update: 2021-06-22

>FIG. 7), and the wild-type BRCA benefit patients with more significant (the HR = 0. 51; 90% CI, 0. 30-0. 88; P = 0. 020) . in At this ASCO
Pay attention to the precise diagnosis and treatment of rare mutations, and start a new journey of integrated diagnosis and treatment in the targeted outpatient clinics

 Time of Update: 2021-06-22

With the support of the hospital, the Lung Cancer Rare Mutation Targeted Clinic will be opened on March 18, 2021, so that patients can receive scientific treatment guidance and precise treatment services .
New study investigates the effect of ORi-guided oxygen titration on hyperoxia-mediated lesions during one-lung ventilation

 Time of Update: 2021-06-22

Masimo Turkish Journal of Medical Sciences 1ORi was launched outside the United States in 2014 and is a non-invasive continuous parameter designed to further understand the oxygen status of patients during supplemental oxygen .
Mol Cell: Scientists have discovered special proteins that can induce certain cancerous tumors

 Time of Update: 2021-06-22

carrying the genetic code of life will continue to be hit in its normal functioning. If you deal with it, these errors will accumulate, which will bring fatal consequences to nuclear organisms, such as cancer and tumors <br
FDA guidelines for patient reporting outcomes in cancer trials measure five core concepts

 Time of Update: 2021-06-22

. These trials usually use standardized efficacy evaluations, use overall survival and tumor measurements, and clinically based Safety evaluation of adverse reactions reported by doctors . </span

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Study of Nervous System

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Massachusetts General Hospital found that the implantable chip can more accurately identify patients at risk of stroke recurrence...

 Time of Update: 2021-06-23

Recent studies have shown that a small chip implanted under the skin can monitor heart rate and rhythm, and help doctors detect atrial fibrillation in patients who have experienced cryptogenic stroke .
Want a good night's sleep?

 Time of Update: 2021-06-22

"The study found that many people who have the habit of listening to music experience a continuous "earworm effect" and a decline in sleep quality .
Nature: FDA approved a landmark new drug, patients are happy, scholars are worried...

 Time of Update: 2021-06-22

S. Food and Drug Administration (FDA) approved Aducanumab, the first new drug to treat Alzheimer's disease in 18 years .
Cell Journal: Restoring miRNA expression can save memory deficits in Alzheimer's disease

 Time of Update: 2021-06-22

In terms of function, experiments confirmed that miR-132 is necessary for the induction of dentate gyrus neurogenesis in vivo, and can regulate neuronal differentiation in human neural stem cells and down-regulate in Alzheimer's disease-related pathology .
The FDA has repeatedly broken the routine, and in the process of launching the "first" new drug for Alzheimer's disease...

 Time of Update: 2021-06-22

[2021-06-07] https:// news-events-human-drugs/fdas-decision-approve-new-treatment-alzheimers-disease[2]The US Food and Drug Administration.
You lie flat, your brain is still learning 20 times faster

 Time of Update: 2021-06-22

A new study published recently also found that in a waking and resting state, brain activity can "play back" the sequence of actions just learned at 20 times the speed.
The consensus on the management of sleep disorders in Parkinson's disease is very clear!

 Time of Update: 2021-06-22

Nervous System Disease Professional Committee of Shanghai Association of Integrated Traditional Chinese and Western Medicine organized domestic Chinese and Western medicine experts in the field of PD, based on evidence-based medicine in recent years
Multiple sclerosis is different in different groups, this drug is more "friendly" to Chinese patients

 Time of Update: 2021-06-22

*For medical professionals' reference only, Teriflunomide provides Chinese patients with multiple sclerosis with a combination of curative effects and high satisfaction .
The latest advances in the diagnosis and treatment of perforator atherosclerosis｜CNA 2021

 Time of Update: 2021-06-22

involves 3 levels and above (diameter ≥15mm) in the horizontal position; ③The LSA blood supply area is : Most of the putamen, the outer part of the globus pallidus, the head and body of the caudate nucleus, the forelimbs of the internal capsule, the upper
How to prevent cardiogenic strokes of different etiologies?

 Time of Update: 2021-06-22

Figure 4 In addition to new anticoagulant drugs for interventional treatment of patients with atrial fibrillation combined with PCI, another popular treatment method in recent years is left atrial appendage closure (LACC) to prevent cardiogenic stroke .

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Immunology News

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Immunity: "harmful" fat may inhibit the body's ability to attack cancer cells by killer T cells

 Time of Update: 2021-06-22

in nutritional availability; researchers all know that fat accumulates in tumors, and fat accumulation It is related to the immune dysfunction of the body, and researchers are not clear about the specific relationship . <br
The 2021 ACR RA Guidelines are released!

 Time of Update: 2021-06-22

In June 2021, the American College of Rheumatology (ACR) issued a guideline for the diagnosis and treatment of rheumatoid arthritis (RA), which is the first version of the guideline that was updated 6 years after the 2015 guideline .
Cell's important finding: The presence of type I natural antibodies similar to 2G12 antibodies in the human body may become a new target for HIV-1 vaccines

 Time of Update: 2021-06-22

The author only tested the reactivity of this FDG antibody to recombinant HIV-1 Env and SARS-CoV-2 S proteoglycans, but this may exclude other types of polysaccharide forms in the body .
PNAS: Butyrate enhances CPT1A activity and promotes fatty acid oxidation and iTreg differentiation

 Time of Update: 2021-06-22

>. Intestinal iTreg cells have been found to be important in the regulation of inflammatory bowel disease (IBD), such as Crohn’s disease (CD) and ulcerative colitis (UC), which may affect any part of the gastrointestinal
Parkinson is actually related to osteoarthritis!

 Time of Update: 2021-06-22

A recent study published in Arthritis Care & Research found that patients with osteoarthritis have an increased risk of Parkinson's disease .
NCB Chen Liang/Yang Pengyuan and others collaborate to reveal the immune memory mechanism of patients recovering from new coronary pneumonia

 Time of Update: 2021-06-22

On June 9, 2021, Nature Cell Biology published an online article titled Single-cell epigenomic landscape
BCMA target is strong, who can be proud of the arena?

 Time of Update: 2021-06-22

At present, CAR-T cell therapy and ADC drugs targeting BCMA have been approved for marketing, and dual-antibody drugs are gaining momentum .
Target the root cause of complement diseases!

 Time of Update: 2021-06-22

>News on June 14, 2021 // - Novartis recently announced the data of a phase 2 clinical study (NCT03896152) of iptacopan (LNP023) for the treatment
Air pollution caused RA attacks?

 Time of Update: 2021-06-22

In the context of this research, Professor Bernard and his collaborators from La Peroni Hospital in France carried out Further study, report the 10-year results of the initial cohort of early RA patients, the ESPOIR cohort, and outcome predictors .
Science Immune resident forces at the edge of the brain: myeloid cells in the meninges

 Time of Update: 2021-06-22

The following focuses on the interpretation of the first paper: In order to find the source of the marginal myeloid cells of the central nervous system, the authors connected the circulatory systems of UBC-GFP wild-type mice through surgery .

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Infection

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90.4% overall protective power recombinant protein new crown vaccine candidate phase 3 clinical results...

 Time of Update: 2021-06-23

On June 14, 2021, Novavax announced that its recombinant protein-based nanoparticle new crown vaccine candidate NVX-CoV2373 has reached the primary endpoint in a pivotal phase 3 clinical trial, with an overall protective efficacy of 90.
The WHO re-examines Italy's blood samples in 2019 and more studies find that when the new crown epidemic is rewritten...

 Time of Update: 2021-06-23

On the 9th local time, the National Tumor Research Institute of Milan, Italy, issued a press release stating that they provided the WHO with blood samples containing antibodies to the new crown virus collected in 2019.
Hisun Pharmaceutical: Linezolid tablets obtained drug registration certificate

 Time of Update: 2021-06-23

7499 million, of which the domestic market sales were approximately 3,244.
Bojian Aducanumab is about to usher in trial!

 Time of Update: 2021-06-23

In January 2021, Biohaven Pharmaceuticals announced that its EAAT2 inhibitor Troriluzole had once again failed in a phase II/III clinical study for the treatment of mild to moderate Alzheimer's disease .
The first in the world!

 Time of Update: 2021-06-23

A patient with colorectal cancer who has received anti-PD-1 monotherapy for a long time experienced a cytokine storm in his body after being vaccinated with this vaccine .
What are the opportunities and challenges faced by the nasal spray vaccine in the "front line" of the new crown virus invasion...

 Time of Update: 2021-06-23

Although the currently developed injectable new crown vaccine can effectively stimulate the body's antibody and cellular immune response, they cannot effectively stimulate the mucosal immune response .
Sales of 5 star drugs have soared!

 Time of Update: 2021-06-23

com, in 2020, the sales of proprietary Chinese medicines in physical pharmacies in cities in China exceeded 100 billion yuan, a year-on-year decline of 4.
"Pharmaceutical Speed Reading Society" 16 batches of unqualified drugs Qinhao Pharmaceutical won the first I...

 Time of Update: 2021-06-23

submitted by various medical institutions according to the procurement category . The purchase period of this centralized purchase is 2 years, calculated from the actual implementation date
Another domestically-made new crown inactivated vaccine has been approved for use on the market

 Time of Update: 2021-06-22

On June 9th, the first batch of Covey's new coronavirus inactivated vaccines independently developed
Novavax's new crown vaccine has an overall effective rate of 90%, which is equally effective against multiple variant viruses

 Time of Update: 2021-06-22

The US biotechnology company Novavax said on Monday that its new coronavirus vaccine (NVx-CoV2373) has been proven safe in phase III clinical trials with nearly 30,000 participants in 119 locations in the United States and Mexico.

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Digestive System Information

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Multiple research results of tislelizumab unveiled at ASCO 2021

 Time of Update: 2021-06-23

repair defect (dMMR) The data of the Phase 2 clinical study (RATIONALE 209 study) of patients with solid tumors was officially announced . The RATIONALE 302 study is the first global phase 3
Enterprise Dynamics AstraZeneca's organizational structure adjustment Qian Wei appointed as the chief of Junshi Bio...

 Time of Update: 2021-06-23

> On June 7, two well-known pharmaceutical companies, AstraZeneca and Junshi Biological, received new news about internal changes, related to structural adjustments and related personnel
The first first-line immunotherapy for gastric cancer refreshes the survival period "The Lancet" publishes an important milestone

 Time of Update: 2021-06-23

The US FDA approved Opdivo (nivolumab), a blockbuster PD-1 inhibitor, in combination with chemotherapy for the first-line treatment of advanced or metastatic gastric cancer, gastroesophageal junction (GEJ) cancer and esophageal adenocarcinoma .
How to recommend the emergency diagnosis and treatment of acute pancreatitis based on the latest expert consensus?

 Time of Update: 2021-06-22

Emergency physicians should complete the BISAP score within 24 hours of admission to early predict the severity of acute pancreatitis .
Zejing Pharmaceutical Donafenib, the first domestically-made first-line targeted drug for liver cancer, was officially approved

 Time of Update: 2021-06-22

/> End reference materials: [1]https://mp. weixin. qq. com/s/z5RvfbFlK4qpqcNczvh6qg[2]https://mp. weixin. qq. com/s/ws5vOj2Ht1QePBVEBblIdQ outer! "Nature
Professor Zhu Xiuxuan: Liver cancer is coming?

 Time of Update: 2021-06-22

As mentioned above, most patients with advanced liver cancer receive immunotherapy well tolerated, but the immune-related side effects caused by such drugs The reaction still cannot be completely avoided .
Liver cirrhosis and portal hypertension bleeding-when is transjugular intrahepatic portosystemic shunt (TIPS)?

 Time of Update: 2021-06-22

Transjugular Intrahepatic Portosystemic Shunts[J]? Clin Liver Dis. 2021 May;25(2):345 -356. [2] Expert consensus on the diagnosis and treatment of esophageal and gastric varices bleeding in portal hypertension of liver cirrhosis (2019
Pancreatic Lift and Pancreatic Movement Professor Liang Jun interprets the latest research progress in the field of pancreatic cancer and discusses the direction of early and late treatment

 Time of Update: 2021-06-22

A study published by GUT [1] evaluated the impact of monitoring of high-risk pancreatic cancer patients on long-term survival benefits .
What is the most suitable treatment for patients with multiple diseases and cirrhosis of the liver who have acute kidney injury?

 Time of Update: 2021-06-22

Key points of study: The initial treatment drugs for patients with mild hepatorenal syndrome include albumin, midodrine and octreotide .
Drink less!

 Time of Update: 2021-06-22

SSB intake of more than 1-2 servings/day is also associated with an increase in CAP .

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Endocrine System

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Patients with type 2 diabetes can benefit from two JAMAs calling for more extensive continuous blood glucose monitoring...

 Time of Update: 2021-06-23

-monitoring is a standard part of diabetes self-management, a considerable number of patients do not self-adjust insulin well . > Recently, the Journal of the American Medical
A hundred years of retrospect of the light of medicine-tribute to the 100th anniversary of the discovery of insulin 2021...

 Time of Update: 2021-06-23

, a media exchange meeting for the 100th anniversary of the discovery of insulin and 2021 "Healthy China E Get Up" Diabetes Popular science activities started to be held in Beijing .
Hutchison Whampoa Sofantinib's new indication will be approved soon

 Time of Update: 2021-06-23

On December 30 last year, Sofantinib was just approved for marketing for late-stage well-differentiated neuroendocrine tumors of non-pancreatic origin .
Not only to reverse diabetes, but also to stop antihypertensive drugs?

 Time of Update: 2021-06-22

In addition to alleviating type 2 diabetes, dietary intervention can also effectively control the patient's blood pressure and stop or reduce the need for patients to take antihypertensive drugs .
Obesity increases second cancer risk in women with breast cancer

 Time of Update: 2021-06-22

This article is from the NEJM Journal Watch High BMI Increases Risk of Second Cancers in Women with Breast Cancer.
【Cell Reports】Heavy!

 Time of Update: 2021-06-22

Recently, researchers from Northwestern University in the United States published a paper entitled "The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding" in Cell Reports .
New ideas, new drugs, new recommendations, writing experts will take you to "Consensus"

 Time of Update: 2021-06-22

First of all, Professor Ma pointed out that for patients with T2DM combined with CVD, the "Consensus" introduced to cardiologists a new type of hypoglycemic drugs that can effectively reduce blood sugar and improve prognosis, including glucagon-like drugs.
Lipid-lowering drugs enter the treatment of "hyperthyroidism"?

 Time of Update: 2021-06-22

Introduction: Observational studies have found that statin users are significantly less likely to develop Graves' ophthalmopathy, and this benefit is especially obvious among men .
Anti-diabetic martial arts, how does saxagliptin work together?

 Time of Update: 2021-06-22

>. In mild renal insufficiency, that is, when creatinine clearance (CrCI) ≥50 ml/min (corresponding serum creatinine level ≤1. 7 mg/dl for men and ≤1. 5 mg/dl for women), saxagliptin
8 Tuo of poo that has passed through a thousand years, let Harvard scientists find clues to cure diabetes Nature

 Time of Update: 2021-06-22

Recently, "Nature" published a paper on ancient human feces, which provided new clues for the study of type 1 diabetes, obesity and other diseases .

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Blood System

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Overview of clinical projects of cancer cell immunotherapy: over 2000 pipelines CAR-...

 Time of Update: 2021-06-23

, IQVIA, a world-renowned medical industry consulting company, and the non-profit organization Cancer Research Institute (CRI) published an analyst report titled The clinical pipeline for cancer cell therapies in Nature Reviews Drug Discovery
The complete remission rate of refractory patients exceeds 30% CD37 targeted ADC combination Phase 2...

 Time of Update: 2021-06-22

of relapsed/refractory (R/R) diffuse Positive results were obtained in a phase 2 clinical trial of large B-cell lymphoma (DLBCL) . The trial results showed that the combination therapy achieved
What are the important developments of innovative therapies developed around p53 targets in the past 40 years?

 Time of Update: 2021-06-22

detailed, innovative therapies around this target have not been born for more than 40 years . Among them, there are some scientific challenges . </span
2021 EHA Big Coffee Interview Professor Cao Xinxin: Interpretation of Research Progress in Light Chain Amyloidosis

 Time of Update: 2021-06-22

(PR) 21. 1%, and no remission (NR) 31. 1% . The median OS of patients with ≥VGPR at 1 month has not yet reached, while the median OS of patients with only PR or NR
The prognosis of AML with other gene mutations in different IDH mutation subgroups is different

 Time of Update: 2021-06-22

Based on this, some researchers retrospectively analyzed the prognosis of newly diagnosed AML patients with IDH mutation who received IC treatment based on data from three prospective clinical trials of the French Acute Leukemia Association (ALFA) .
NSMB Xu Dong Group Reveals New Pathogenesis of Fanconi's Anemia

 Time of Update: 2021-06-22

to cells and living organisms and is difficult to repair . The stagnation of replication forks caused by replication pressure is also the main source of cancer cell genome
EHA 2021: The latest results of clinical trials of CRISPR and Vertex for the treatment of hereditary hemoglobinopathy are positive

 Time of Update: 2021-06-22

, and the oncolytic virus has entered the fast lane Yimai New Observation Click on the picture and register now June 16, 2021 /MedClub News/--A few days ago, CRISPR Therapeutics and Vertex Pharmaceuticals announced the Phase 1/2 clinical trial data
CD37 ADC combined with CD20 monoclonal antibody in the treatment of DLBCL, clinical results are positive, Yi Mai Meng broke the news

 Time of Update: 2021-06-22

virus has entered the fast lane Yimai New Observation Click on the picture and register now June 16, 2021 /Healthcare News eMedClub News/--Recently, Debiopharm, a global biopharmaceutical company, announced the Phase 2 results of Narratuximab
[Lymphoma Microcourse 2021EHA] EP636 First-line Treatment of Ibrutinib in Patients with Chronic Lymphocytic Leukemia: 7-year follow-up of the RESONATE-2 study

 Time of Update: 2021-06-22

Today I will mainly introduce an abstract on EHA in 2021: First-line treatment of Ibrutinib in patients with chronic lymphocytic leukemia: 7-year follow-up of the RESONATE-2 study .
EHA hot spot: A number of phase III studies of C5 complement inhibitor Crovalimab have entered the recruitment phase, and the research and development in China is synchronized with the global

 Time of Update: 2021-06-22

At the 26th European Annual Conference on Blood (EHA) this year, crovalimab announced three important research designs, including two important phase III clinical trials (COMMODORE 1, COMMODORE) 2), and a study related to the burden of PNH disease (COMMODORE BoI).

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The State Council issued a document!

 Time of Update: 2021-06-23

is the reform list of license matters set by the central level (2021 national version). ) A total of 523 items. The second category is the list of permit reforms set by the central level (2021 Free Trade Pilot Zone Edition) with a total of 69
A pharmacy fined 2 million yuan, the strictest supervision is coming

 Time of Update: 2021-06-23

> . If the random-checked drug retail chain stores are set up across provinces (autonomous regions, municipalities), the provincial drug regulatory authority that organizes licensing inspections may conduct joint
"Pharmaceutical Speed Reading Society" Novartis iptacopan treats IgA nephropathy stage 2 clinical...

 Time of Update: 2021-06-23

>. (PR Newswire) > Preliminary clinical results of HER3-targeted ADC for non-small cell lung cancer are positive >Preliminary clinical
Tianyao Pharmaceutical's adrenaline hydrochloride injection passed the consistency evaluation of generic drugs

 Time of Update: 2021-06-23

In November 2019, Jinyao Pharmaceutical submitted a supplementary application for consistency evaluation to the Drug Evaluation Center of the National Medical Products Administration and was accepted .
These drugs will be "prescription outflow" and another province will start pilot projects!

 Time of Update: 2021-06-23

of prescription data in various medical institutions, and carry out hospital prescription extension (including hospital HIS system, Internet medical service system, etc. ), intelligent online review of prescriptions, chronic disease renewal
Doctor's medical record signature violation, patient died, hospital was presumed fault compensation 490,000

 Time of Update: 2021-06-23

, and the patient was given 25 mg of captopril sublingually. After 5 minutes, the blood pressure was 210/105 mmHg. The patient was again given 25 mg of captopril sublingual and sublingual. Later, the blood pressure began to drop
Latest news from the Food and Drug Administration: The General Administration of Customs has added Changchun Air Port as a drug import port

 Time of Update: 2021-06-22

Since the date of this announcement, Jilin Provincial Institute of Drug Inspection has begun to undertake the inspection of drugs at Changchun Airport .
In this way, intraoperative blood pressure monitoring is more accurate...

 Time of Update: 2021-06-22

In the lateral position, non-invasive blood pressure should be monitored on the non-operative side (lower side), and the error is smaller; 3.
Notice of the State Administration of Traditional Chinese Medicine on Printing and Distributing Guidelines for the Construction of National TCM Emergency Medical Teams

 Time of Update: 2021-06-22

> Article 31 When organizing TCM emergency drills for emergencies, the provincial-level TCM authorities should combine local actual conditions, focus on actual combat, stress practical results, scientifically formulate emergency drill
JAMA: In the context of the regulation of opioids, how do you prescribe pain prescriptions in the emergency department?

 Time of Update: 2021-06-21

investigated the association between the changes in the rate of opioid acquisition of these patients after the PDMP directive was implemented, and the results of the study were published in the latest JAMA</span

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US FDA approves Tembexa: the first smallpox for all ages...

 Time of Update: 2021-06-23

Chimerix recently announced that the US Food and Drug Administration (FDA) has approved Tembexa (brincidofovir) tablets and oral suspensions for the treatment of smallpox .
Oncology NGS industry opens second curve, MRD recurrence monitoring leads industry changes

 Time of Update: 2021-06-23

As an application scenario juxtaposed with early screening and companion diagnosis, the status of recurrence monitoring in the oncology NGS industry has not received enough attention .
Staying up late will "be stupid". During sleep, the brain will start a "detoxification" program to clear the brain...

 Time of Update: 2021-06-23

Recently, researchers from the University of Pennsylvania published an article titled Reduced coupling between cerebrospinal fluid flow and global brain activity is linked to Alzheimer disease-related pathology in PLOS Biology.
Eli Lilly's oral JAK inhibitor Olumiant effectively improves pain/body function...

 Time of Update: 2021-06-23

>The safety results are consistent with the established safety analysis results of oral Olumiant in patients with rheumatoid arthritis . The detailed efficacy data is shown in the table below
FDA Regarding the Disposal of Johnson & Johnson's Covid-19 Vaccine Stock Produced in Emergent...

 Time of Update: 2021-06-22

After performing additional tests, Janssen confirmed the OOS test results and subsequently notified Emergent about the cross-contamination of DS GMP8 with the AZ adenovirus vector vaccine produced in other areas of the EMOB plant .
2020 Medical Insurance Statistics Bulletin released!

 Time of Update: 2021-06-20

The hospitalization expenses fund payment within the policy scope of secondary and lower-level medical institutions was 87.
How do the potential "culprits" of various neurological diseases damage the brain?

 Time of Update: 2021-06-20

Scientists examined the brains of patients with Alzheimer's disease after death, and found evidence of splicing-related defects in the cells, that is, spliceosome components tangled with tau protein aggregates were found in the cells .
Financing continues to explode, and Internet medical companies such as Kuaiyao are "healthy...

 Time of Update: 2021-06-20

In 2014, Renhe Pharmaceuticals invested 5 million yuan in angel rounds to establish Dingdang Kuaiyao, starting with O2O drug delivery business .
Biogen brings the gospel to Alzheimer's disease for the first time since 2003...

 Time of Update: 2021-06-20

According to the terms of accelerated approval, the FDA requires Biogen to conduct a new randomized controlled clinical trial to verify the clinical efficacy of the drug .
The industry proposes to write a new USP chapter for visual inspection to achieve standardization and consistency of visual inspection

 Time of Update: 2021-06-20

They suggested the development of a harmonized pharmacopoeia chapter, which includes the use of a "universal standard set" to train visual inspectors, confirm methods, and verify results .

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Experts interpret the research progress of ASCO advanced urothelial cancer treatment in 2021

 Time of Update: 2021-06-22

The ASCO meeting reported the five-year follow-up update results of the second-line immunotherapy KEYNOTE045 study of advanced urothelial cancer .
[2021 ASCO] The importance of early new endocrine therapy for mHSPC patients from the TITAN study on the quality of life of patients

 Time of Update: 2021-06-22

the latest cutting-edge developments. The conference announced a number of blockbuster research results in the field of urinary oncology . This article will share the most
2021 ASCO Locally advanced MIBC: When will dual immunity + radiotherapy replace cystectomy?

 Time of Update: 2021-06-22

The IMMUNOPRESERVE-SOGUG study explored the results of dual immunotherapy + simultaneous radiotherapy for locally advanced muscle invasive bladder cancer (MIBC) .
Evidence-based guidelines, advancing with the times-2021 version of "CSCO Prostate Cancer Diagnosis and Treatment Guidelines" is officially released!

 Time of Update: 2021-06-18

of metastatic prostate cancer . It is expected that more Chinese prostate cancer research will be written into the guidelines in the future, which will eventually guide clinical practice
The latest 5-point cancer methylation article published

 Time of Update: 2021-06-02

/> Literature name: Genome-wide DNA methylation profiling of leukocytes identifies CpG methylation signatures of aggressiveprostate cancer PCa is the most common cancer among men in the United States and the second leading cause of cancer deaths. <br
Erectile dysfunction may be related to cardiovascular disease?

 Time of Update: 2021-06-02

3. ED should be regarded as a risk factor for cardiovascular disease.
Molecular Cancer | Significant progress!

 Time of Update: 2021-06-02

In summary, the study found that the key role of the FOXA1-KDM6A-ARHGDIB axis in suppressing BCa malignancies has been established, and KDM6A and EZH2 have been identified as potential therapeutic targets in the management of BCa.
A case of ureteral obstruction with peak circuit turn

 Time of Update: 2021-06-01

Ureteral metastasis of non-small-cell lung cancer: a case report.
Clinical Essentials | Overview of Ultrasound Manifestations of Kidney Stones and Ureteral Stones

 Time of Update: 2021-06-01

12 Ureteral stones (transition of ureter and bladder) Fig 13 Extravasation of renal pelvis Clinical 1.
Prof. Cui Chuanliang: Interpretation of the key points of the 2021 CSCO Urothelial Carcinoma Diagnosis and Treatment Guidelines Update

 Time of Update: 2021-05-22

in Beijing, the capital. As one of the most influential academic festivals in the field of oncology in China, big coffees from all over the country gathered together to witness the update of multiple guidelines

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