Active Ingredient News

Several provisions of the Supreme People's Court on evidence in civil proceedings on intellectual property rights

2020 domestic antibody new drug research and development pattern

Health care negotiations: Chinese characteristics "health insurance" cliff!

How to rob the drug king Shumeile 10 billion self-free market?

Authoritative List: 10 start-ups to watch in 2020!

NASH drug action target distribution and representation in the study drug inventory

"Research and development of a brother" name is not false! 49 class 1 new drugs bright eyes, 12 first imitation winning tickets in hand, attack slow-disease drugs, high-end preparations

The latest trends in PD-1/PD-L1 worldwide in 4,400 clinical trials are of concern

Novart, Pfizer, Lilly go high-profile to see how drug companies play "Internet Plus"

The five ministries jointly identified Xinda Bio as the "National Enterprise Technology Center"

The registration volume of feed processing enterprises in China increased by 68.4% year-on-year in the first three quarters.

Ministry of Agriculture and Rural Affairs: The resumption of pig production nationwide has accelerated the improvement of pork supply

1.32 yuan / catty! The sky-high price of grain storage in China is northeast corn! The country's pig production capacity has been restored to 88% year-on-year.

Global food prices are rising, and Chinese farmers are snapping up feed grain around the world

Soybean, another trap?

Ministry of Agriculture and Rural Affairs: Pork prices rose during the Spring Festival on New Year's Day

From November 30, six provinces in central and southern China banned the transfer of foreign pigs, "point."

At a critical moment, there's a fire in the cornfield! Nearly five hundred acres!

5 pig breeding enterprises to expand production investment of nearly 20 billion yuan! The price of pigs has reached four

Heart has the north foot there is a road - 2020 broiler industry chain "to find the north trip."

1 case of double genotype less protrusion cytoma histology, molecular, radiology and pathogenic characteristics

Cell interpretation! How does uncovering nerve tissue protect pancreatic cancer cells from hunger?

Home-made PD-1 therapy! Baiji Shenzhou Baizean ® (for Reilly zhu single resistance) treatment of non-small cell lung cancer Phase 3 clinical success!

Targeted drugs are constantly available, and breast cancer may become a manageable chronic disease

Nature sub-journal interpretation! How can cancer cells become more susceptible to death?

Cancer Cell overview article interpretation! How to develop a new generation of cancer therapy for CAR-T cell engineering modification?

Tumor immunotherapy upgrade! AstraZenecom's Imfinzi new dosing program (1500mg once every 4 weeks) is approved by the FDA!

Br J Cancer: Comparison of the efficacy and safety of topological tycon and beloticon in a single therapy for relapsed small cell lung cancer

New drug for lymphoma! CD19 Target Antibody Association Drug (ADC) loncastuximab tesirine (Lonca) is under FDA priority review!

T-cell activation and checkpoint suppression: triple immunotherapy to treat glioblastoma (GBM) 18-month survival rate of up to 50-70%!

Nat Med: How immune memory is formed during the recovery phase of new coronavirus infection

Science sub-journal interpretation! Does air pollution really make the COVID-19 epidemic even more deadly?

Scientists have developed a new nasal spray that promises to prevent and treat the infection and spread of coronaviruses such as SARS-CoV-2!

Cell Metabolism: Key metabolic path paths regulate T-cell activity

Science: Reveals the mechanisms of super-powerful synthetic nanoantibodies and new coronavirus

The first BTK inhibitor to treat immunoplate plateroid reduction (ITP)! FDA grants Sanofi rilzabrutinib fast track eligibility!

Is honey really good for your body's health?

New medicine for rare diseases! C3 inhibitor pegcetacoplan received FDA priority review: Phase 3 efficacy beats heavyweight C5 inhibitor Soliris

Cell Stem Cell: How smoking exacerbates the infection of the new coronavirus in the lungs

Nodding itch new drug! FDA grants OSMR beta-targeted blocking monoantigen vixarelimab breakthrough drug eligibility!

Nat Neurosci: A link between overactivation of brain astroid cells and the onset of Alzheimer's disease

New drugs for children with epilepsy! Vesei Fycompa (Wexter ®, Villenem Panai) has been approved by the European Union to expand the applicable population, has been listed in China!

Int. J. Mol. Sci: New study could help relieve Alzheimer's disease

New antipsychotic drugs! ALKS3831 (O nitrogenpin/samidorphan) was rejected by the FDA for treatment of schizophrenia/biphasia type I disorder

Aging cell: Alzheimer's disease is diagnosed according to the retina

Nature interpretation! How do brain neurons affect the choices the body makes?

Prog. Neurobiol: The effects of chronic drinking on the brain's immune system

Cell: Changes in Tau protein in people with Alzheimer's disease with age

JNNP: Risk Score for Middle-aged and Alzheimer's Disease and Ageing Awareness: A Population-Based Twin Study That Followed For More Than 20 Years

New drug for epilepsy! FDA approves Ukip vimpat (lacosaamine): Treatment of primary all-round strong-straight convulsive seizures (PGTCS)!

Sanofi's four-price flu vaccine, Supertek, has been approved in the European Union to prevent influenza

Heart: Effects of anti-hypertension drugs and antibiotics on the progression of abdominal aortic aneurysms

NEJM: Hydroxychloroquine or hydroxychloroquine combined with azithromycin to treat new coronary pneumonia is not significant

Lancet Infect Dis: Candidate Covid-19 inactivated vaccine Coronac has a good effect

Signal Transduct Target Ther: A team of professors at Shandong University has clarified the subcellular positioning of 28 new coronavirus proteins

Science: Watch out! The new coronavirus D614G mutant strain is more replicable and more propagated!

Nature: The deadly virus, once used as a biological weapon in the United States, continues to explode, and CRISPR technology has succeeded in finding an antidote

Lancet Gastroen Hepatol: HCV Risk Study of Male Behavioral Groups

The Lancet: AstraZenecon's chimpanzee adenovirus vector COVID-19 vaccine induces a strong immune response in older adults

ViiV's once-in-two-month long-acting injection cabottegravir, used to prevent HIV, has been named the FDA's breakthrough therapy

JCC: Increased coagulation enzymes in the mucous membranes of the intestines are associated with the continued progression of inflammation in Crohn's disease

2020 China's top ten digestive tract clinical research released! New use of old medicine, jaundrel can prevent the recurrence of intestinal pneumoone

JCC: Effects of biologic therapy on the probability of AD patients being positive for SARS-CoV2

There is an odor in the mouth, indicating a state of health

Clin Gastro H: The sensitivity of fecal immunochemical testing to colorectal cancer depends on the stage and location of the patient's illness

JCC: Can patients with inflammatory bowel disease terminate the treatment of hydrogenated pine when receiving Inflixi single anti-maintenance therapy?

JCC: It is not cost-effective for patients with remission ulcerative colitis to continue using anti-TNF drugs compared to withdrawal therapy

Dig Dis Sci: Moderate to severe ulcerative colitis patients who try to use inflixi monoantigen on behalf of 5-amino-salicylicate treatment will not be effective

JCC: Statins may reduce inflammatory bowel disease

Dig Dis Sci: Analysis of the therapeutic effects of inflixi monotherapy in early Crohn's patients

Blood: Recombinant FVIII drug Rurioctocog alfa pegol preventive treatment of haemophilia type A

Blood: Post-HCT CD4-T cell reconstruction predicts survival prognostics in patients with acute GvHD

Clin Cancer Res: Multiple myeloma . . The "high dose" of amine is not loved

Blood: Do high-risk Philadelphia chromosomal-negative ALL adult patients need alllo-HSCT?

Inventory: A selection of Lancet studies on November 21, 2020

Fda suspends clinical trials of CAR-T therapy UCTCS1 for multiple myeloma

The Lancet: Nuclear export inhibitor XPOVIO significantly prolongs the progression-free survival of patients with relapsed or refrectable multiple myeloma

Blood: Salbonate enhances the anti-tumor activity of CRM1 inhibitors

Blood: Activated AKT triggers CLL by overactivated Notch1→ Richter conversion

JAMA Oncology: Prognostic assessment of the deactivation of tyrosine kinase inhibitors in patients with chronic myeloid leukemia

JAMA Pediatrics: Weight worries and dieting are on the rise among teens, or lead to depression

Less re-evidence! Pay attention to the new ideas of Zinlida particles to prevent and control metabolic diseases such as obesity and type 2 diabetes

NEJM: Golimumab partially restores islet function in young people with new type 1 diabetes

Diabetes Care: A global epidemiological analysis of end-stage kidney disease associated with diabetes

Diabetes Care: Relationship between severe hypoglycemia and heart structure and function and cardiovascular event risk in older diabetics

JCEM: Bone metabolism in adolescents undergoing bariatric surgery

JAMA:omega-3 fatty acids had no significant clinical benefits for high-risk cardiovascular patients who were receiving statin therapy

Metabolism: MAFLD and CKD Risk

Diabetes Care: The association between pre-pregnancy diabetes and gestational diabetes in pregnant women and congenital malformations in newborns

Lancet: Effects of postoperative radiotherapy strategies on PSA processes for prostate cancer

Back pain is often, perhaps these 3 diseases in the "weird", it is best to check!

A new non-opioid postoperative analgesic drug, the hydrochloric acid bubicarin implant, is officially available in the United States

China's pain health index was first released, and citizens were the most likely to fall into six misconceptions about pain.

Is the patient's pain normal and must be tolerated? Experts say patients who can't survive pain are wrong!

JAMA Pediatr: Maternal epidural analgesia leads to an increased risk of autism in future generations.

BMC Musculoskelet Disord: Craniofacial therapy is effective in treating chronic pain.

Complement Ther Med: The VR program can be used as an aid for pain control during peri-surgical periods.

Inventory: A selection of Lancet studies on September 26, 2020.

Lancet: Gabba spray is used for the treatment of chronic pelvic pain.

CHMP: Positive evaluation of postoperative pain in exPAREL (Bubicain liposome suspension).

Multivariable risk prediction model for neurosurgery

Premature children with indoor hemorrhage clear the relationship between blood breakdown products in cerebrospinal fluid and hydrocephaline.

The level of lactate in the subcavity of the cobweb film predicted the occurrence of hydrocephalus after aSAH.

ADC imaging for intracranial tumor puncture biopsy and tumor level determination

Decline in serum UA levels indicates prognosis in TBI patients

When did patients with mild cranial trauma who were initially CT-positive review CT?

Never assess the condition of an elderly TBI based on a GCS score alone

CT flat sweep predicts the expansion of cerebral hemorrhage hematoma and BAT scoring method

CTA spot signs combined with brain haemorrhage score predict brain haemorrhage prognosis is not valuable

Using improved MRS to identify glioma IDH mutation in the body