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CStone Pharmaceuticals announced the CS1002 (anti-CTLA-4 monoclonal antibody) and CS1003 (anti-PD-1 monoclonal antibody) phase Ib study data in patients with advanced solid tumors at the 2021 ESMO annual meeting

 Time of Update: 2021-10-11

dose levels, namely the regular dose of CS1002 (1 mg/kg Q3W, up to 4 doses, group A), and the lower dose of CS1002 (0. 3 mg/kg Q6W, Group B) . >As of March 1, 2021
The "2020-2021 Chinese Family Standing Medicine Listed Brands" campaign is underway

 Time of Update: 2021-10-11

family with a scientific and practical family-prepared medicine guide, "2020 -In 2021, China's household standing medicines will be listed on the "Brands" campaign, which is currently under application . <br
Kangfang Biology initiates global phase 2 clinical treatment of atopic dermatitis with IL-4Rα monoclonal antibody

 Time of Update: 2021-10-11

And safety . >Previously, AK120 has completed a single-dose escalation phase 1a clinical study in healthy subjects and a multi-dose escalation phase 1b clinical study
Capital scrambles to lay out, digital therapy becomes "new medical outlet"

 Time of Update: 2021-10-11

For example, Shangyi Technology, which developed the first digital therapy app in China .
The Phase III clinical trial of Exploratory Pharmaceuticals Proklamide for the treatment of hospitalized patients with new crown was approved by Brazil ANVISA

 Time of Update: 2021-10-11

to explore the effectiveness and Security . The primary endpoint of the clinical trial is the time it takes for the patient to recover within 30 days, and the secondary endpoint is the 30-day
The results of the second phase of Hubei Province drug quality sampling inspection in 2021 announced 13 batches that did not meet the standards

 Time of Update: 2021-10-11

Supervision and Sampling Inspection Plan, the drug supervision and administration departments at all levels have conducted random inspections on the drug quality of the drug production, operation and use units of the province <span
Innovent and UNION therapeutics reached a strategic cooperation to introduce next-generation PDE4 inhibitors for the treatment of inflammatory skin diseases

 Time of Update: 2021-10-11

on immunology and infectious diseases and has multiple clinical stage pipelines, today The two parties jointly announced that UNION’s main drug candidate for the treatment of inflammatory skin diseases, orismilast, a potential best-in-class PDE4
Hengrui Medicine's "Pregabalin Sustained-Release Tablets" Approved for Listing in China

 Time of Update: 2021-10-11

ArticleMedicine GuanlanToday, China's National Food and Drug Administration (NMPA) announced that the pregabalin sustained-release tablets declared by Hengrui Medicine have been approved for listing in China .
Academician Joint Laboratory Guangzhou was established to accelerate the clinical transformation of medical scientific research results in the Greater Bay Area

 Time of Update: 2021-10-11

　　"2021 Guangdong-Hong Kong-Macao Greater Bay Area Biomedical Summit Forum and the First Medical Technology Week" was held in Guangzhou on the 24th <span
The completion of the acquisition of two major multinational pharmaceutical companies is related to Novartis and Boehringer Ingelheim

 Time of Update: 2021-10-11

It mainly develops new therapies around a type of intracellular antigen (atypical HLA peptide complex) newly discovered on cancer cells .

Medical World News

One-quarter of Class 1 innovative drugs come from Shanghai. Detailed explanation of the "code" for the development of Shanghai's pharmaceutical industry

 Time of Update: 2021-10-10

Class 1 innovative drugs, a record high, accounting for about a quarter of the national total. One," Zhang Qing, deputy director of the Shanghai Municipal Drug Administration, said recently . </span
The National Health Commission and other eight departments jointly issued the "Guiding Opinions on Promoting the Management of Hospital Safety and Order"

 Time of Update: 2021-10-10

> . It is necessary to improve the leadership mechanism for safety and order management, strengthen the strength of full-time security institutions (security department, section), improve the level
Jiangsu introduced 30 measures to promote the high-quality development of the biomedical industry

 Time of Update: 2021-10-10

. The main purpose of Jiangsu's "Several Policy Measures" is to optimize and strengthen the province's biomedical industry supply chain, and promote the high-quality development of Jiangsu's biomedical industry to a new level .
The latest release of the State Food and Drug Administration!

 Time of Update: 2021-10-10

Announcement of the State Food and Drug Administration on the issuance of technical guidelines for clinical trials of in vitro diagnostic reagents (No.
Uncovering the chaos in the cosmetic contact lenses industry: multiple brands use the same medical device registration number

 Time of Update: 2021-10-10

With the strict supervision of the platform, they will choose to cooperate with some online pharmacies and use the advantage of the other party's medical device license to sell cosmetic contact lenses, etc.
The Nobel Prize in Physiology or Medicine is announced!

 Time of Update: 2021-10-10

[A Centennial Award: "New Discoveries Make Life Better"] The Nobel Prize in Physiology or Medicine was first awarded in 1901, and 120 years have passed since .
WHO launches global new crown vaccination strategy: at least 11 billion doses are needed

 Time of Update: 2021-10-09

(Headquarters reporter Zhu He)　　On the 7th local time, WHO Director-General Tan Desai announced the launch of the global new crown vaccination strategy.
Innovative endoscopic weight loss technology can be expected in the future, and Tangji’s “gastric bypass stent system” has been awarded

 Time of Update: 2021-09-28

This shows that the "gastric bypass stent system" has achieved initial success in clinical research on weight loss treatment, and the new technology has a gratifying effect on the control of obesity and metabolic diseases .
Hebei Province Solicits Opinions on the Implementation Rules for the Management of Traditional Chinese Medicine Formula Granules

 Time of Update: 2021-09-19

medicine pieces through water extraction, separation, concentration, drying, and granulation. Under the guidance of Chinese medicine theory, they are formulated in accordance with clinical prescriptions of Chinese medicine and then used
Do not wait for 1.2 million sky-high drugs

 Time of Update: 2021-09-19

2 million high-priced drugs For cancer patients, special tumor drugs and innovative therapies can provide new possibilities for disease treatment, but blockbuster special drugs and innovative therapies are often expensive and social security protection is limited .

Medical Research Articles

New "intestine" technology is coming?

 Time of Update: 2021-10-11

attracted a large number of entrepreneurial teams, well-known pharmaceutical companies and capital to settle in . >In order to promote the accelerated development of scientific
Top 10 Space Biology Companies in the World in 2021

 Time of Update: 2021-10-11

2. RareCyte's total funds raised: US$52 millionRareCyte's Precision Biology™ solution enables customers in oncology and disease research to perform multiple analyses of cells and tissues, thereby bringing new treatment methods and diagnostic tests to the market .
2022 The 19th China Nanjing Educational Equipment and Science, Education and Technology Exhibition

 Time of Update: 2021-10-11

professional exhibition of science, education, technology and equipment in the country. It has formed a significant brand effect and is the best platform for domestic and foreign manufacturers to display and promote scientific and educational
【Live Preview】Operation and maintenance of purified water equipment

 Time of Update: 2021-10-10

to the live broadcast room of Pharmaceutical Network . While technological advancement brings high-efficiency, high-standard and high-quality products to enterprises, it also places higher demands
Antiepileptic drugs can improve the cognitive function of some patients with Alzheimer's disease

 Time of Update: 2021-10-10

>According to a study published in the Journal of Neurology of the American Medical Association on September 27, a cheap anti-epileptic drug can significantly improve the learning, memory and other recognition of Alzheimer’s patients with epileptic activity
Oral COVID-19 medication: effective!

 Time of Update: 2021-10-10

Merck announced on October 1, 2021 that the oral antiviral drug Molnupiravir co-developed with Ridgeback is safe and effective for the treatment of COVID-19 .
The 2021 Nobel Prize in Physics announced!

 Time of Update: 2021-10-10

discoveries of these scientists that the Nobel Prize in Physics can be so "brilliant . " The status of the winners of the Nobel Prize in Physics in the past ten years is as follows
New ways to prevent breast cancer

 Time of Update: 2021-10-10

should recommend individualized risk assessments for patients and advise them to take interventions, from life>. ”>She said these strategies may help reduce hormone-sensitive breast cancer
Treatment of anal cancer precursor lesions can reduce cancer risk in HIV-infected people

 Time of Update: 2021-10-09

HSIL . >Palefsky said: "ANCHOR's data shows for the first time that even in high-risk groups, anal cancer can be prevented, such as HIV-infected people, who often have HSIL, which
Difficult to choose microcrystalline cellulose?

 Time of Update: 2021-10-09

The microcrystalline cellulose series products produced by Dongchen Pharmaceutical are comparable in quality to imported products, do not contain ammonium ions, have low compatibility risks, and are complete in models.

Medical Science News

From "buy, buy, and buy" to "sell, sell, and sell," this pharmaceutical company sold the equity of four subsidiaries during the year

 Time of Update: 2021-10-10

to the present . Prior to this, Fosun Pharma also announced plans to sell 25% of Tianjin Pharmaceutical, 100% of Foshan Chanxi, and 75% of Taizhou Zhedong Medical Care Investment <br
In order to make the company's development strategy more focused, a pharmaceutical company cancelled another branch

 Time of Update: 2021-10-10

Regarding the reason for the cancellation of the liquidation, it clearly stated that it is to reduce the company's management costs, fully integrate and optimize the existing resource allocation, and improve the company's overall operating efficiency .
39 million dollars!

 Time of Update: 2021-10-10

According to the agreement, Sino-US East China will grant Daewon the exclusive development, production and commercialization rights in Korea for the global innovative oral small molecule GLP-1 product TTP273, which is under clinical phase II research .
Just now, the 2021 Nobel Prize in Chemistry was announced!

 Time of Update: 2021-10-10

The 2018 Nobel Prize in Chemistry was awarded to American scientist Frances H.
In order to improve the financial structure, this pharmaceutical company plans to "clear out" its core assets!

 Time of Update: 2021-10-10

From the perspective of the industry, the sale of Jinbao Pharmaceutical by Jilin Pharmaceutical Holdings is just the beginning, and it may continue to dispose of assets in the future .
The latest study finds that targeting fatty acid synthesis pathways can effectively inhibit the new coronavirus

 Time of Update: 2021-10-09

that the targeted fatty acid synthesis pathway can effectively inhibit the new coronavirus The latest research found that the targeted fatty acid synthesis pathway can effectively inhibit the new coronavirus <p
Stay young, start from the cell

 Time of Update: 2021-10-09

Most interestingly, Ferbeyre said, inhibiting these enzymes can stop the growth of prostate cancer cells, which suggests that HTC may be a key target for the development of new therapies for various cancers, including prostate cancer .
Epigenetic therapy combined with immunotherapy to treat tumors makes a breakthrough

 Time of Update: 2021-10-09

, significantly reduces the immune side effects of ORY-1001, and effectively inhibits the growth of triple-negative breast cancer, melanoma or colon cancer in animal models . ><span
Research reveals new strategies for the development of antiviral drugs for RNAi inhibitors

 Time of Update: 2021-10-09

> Research reveals new strategies for the development of antiviral drugs
How does the broccoli eaten in the stomach turn into anti-cancer molecules?

 Time of Update: 2021-10-09

acid) to produce endogenous I3C and DIM, and intestinal bacteria The group played an important role in this process . > In summary, this work found that LTr1 may have medicinal value

Medicines Company News

Kinetisol? technology broadens the preparation space and analyzes its application in the preparation of pharmaceutical amorphous solid dispersions

 Time of Update: 2021-10-11

tablets still have serious food effects and high variability. Patients need to take 1920 mg of the drug daily, which greatly reduces medication compliance. Verofenib prepared with Kinetisol technology- Hypromellose acetate succinate
? Patent analysis of small molecule drug design (WuXi AppTec ddsu article)

 Time of Update: 2021-10-11

in the human non-small cell lung cancer NCI-H358 subcutaneous xenograft tumor model. Effective . At a dose of 3 mg/kg, 1-11A has a strong inhibitory effect on tumor growth, while increasing
Innovent announced the preliminary results of the Phase Ia dose escalation study of IBI315 (anti-Her2/PD-1 bispecific antibody) in patients with advanced solid tumors at the CSCO annual meeting in 2021

 Time of Update: 2021-10-10

Professor Xichun Hu from the Cancer Hospital of Fudan University said: "IBI315 has shown good safety and preliminary effectiveness in the phase Ia study, and preliminary verification of the bispecific antibody design combining targeted therapy and immunotherapy .
How to write a clinical risk management plan for CAR-T cell therapy products that meets the registration requirements

 Time of Update: 2021-10-10

[format] can be received free of charge (2) The new Drug Administration Law will be implemented on December 1, 2019. Approved by the drug regulatory department of the State Council, drug marketing license holders should develop a post-marketing
Aceclofenac of non-steroidal anti-inflammatory drugs (NSAIDs)

 Time of Update: 2021-10-10

Aceclofenac, as a non-steroidal anti-inflammatory drug (NSAID), has been approved to relieve pain and inflammation of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis .
Medical companies join hands to carry out chip-level source innovation research

 Time of Update: 2021-10-10

with medical high-tech companies to focus on major neurological disease research and brain science prospective research, and jointly build a brain science innovation center . > ><span
Is the target CDK2 the highest stage clinical phase III worthy of further follow-up?

 Time of Update: 2021-10-10

Among them, the targeted regulation of tumor cell cycle to change the apoptotic state of tumor cells has been clinically proven to be effective, and the specific representative species is the CDK family inhibitor .
Who can change the pattern of atopic dermatitis treatment?

 Time of Update: 2021-10-10

Two key phase III trials of Lebrikizumab, another IL-13 targeting antibody, ADvocate1 and ADvocate2, also reported reaching the 16-week EASI-75 primary endpoint.
World Alzheimer's Day: How to improve the safety, compliance and accessibility of medicines?

 Time of Update: 2021-10-01

of Alzheimer's disease medications Dosage form . Among them, transdermal patch is one of the important research directions . Compared with oral
How does "machine learning" help new drug development?

 Time of Update: 2021-10-01

Machine learning (ML), as a branch of artificial intelligence, has multiple methods used in the drug discovery process to predict the molecular characteristics, biological activities, interactions, and adverse reactions of new chemical entities .

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