The Instruction of 8-Azabicyclo[3.2.1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)-

The Use of 8-Azabicyclo[3.
2.
1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)- in the Chemical Industry

8-Azabicyclo[3.
2.
1]octane-3-thiol, 8-methyl-, hydrochloride, also known as mefloquine hydrochloride, is an antimalarial drug that has been used in the treatment of malaria since the 1970s.
However, in recent years, it has gained popularity in the chemical industry due to its unique chemical properties.
In this article, we will explore the instruction of 8-Azabicyclo[3.
2.
1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)- and its uses in the chemical industry.

Structural Formula and Characterization

The structural formula of 8-Azabicyclo[3.
2.
1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)- is C18H15ClFN4OS.
It is a white to off-white solid that is soluble in water and organic solvents such as ethanol and methanol.
It has a melting point of 230-235°C and a molecular weight of 337.
86 g/mol.

Preparation and Synthesis

8-Azabicyclo[3.
2.
1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)- can be synthesized through several methods, including the following:

1. Synthesis via reductive amination
   This method involves the reduction of 8-azabicyclo[3.
   2.
   1]oct-3-one with ammonia and subsequent reaction with methyl iodide to form the desired product.
   
2. Synthesis via halogenation
   This method involves the addition of chlorine to 8-azabicyclo[3.
   2.
   1]octane-3-one to form the desired product.
   

Applications in the Chemical Industry

8-Azabicyclo[3.
2.
1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)- has several uses in the chemical industry, including the following:

1. Pharmaceuticals
   The unique chemical properties of 8-Azabicyclo[3.
   2.
   1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)- make it an effective antimalarial drug.
   It is commonly used to treat malaria in tropical regions around the world.
   
2. Intermediates in the production of pharmaceuticals
   8-Azabicyclo[3.
   2.
   1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)- can be used as an intermediate in the production of other pharmaceuticals.
   For example, it can be converted to 4-aminoquinoline, a compound that is used in the treatment of malaria and other diseases.
   
3. Catalyst in chemical reactions
   8-Azabicyclo[3.
   2.
   1]octane-3-thiol, 8-methyl-, hydrochloride (1:1), (3-exo)- can be used as a catalyst in various chemical reactions, such as the polymerization of styrene and the hydrolysis of esters.
   
4. Detection of hydrochloric acid
   8-Azabicyclo[