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Biochemistry News

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Biotechnology News

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Theory-Mechanism-Clinical, multi-target intervention of Jinlida granule has significant effect on diabetes

 Time of Update: 2021-04-19

gave an in-depth explanation on the prevention and treatment of diabetes and the clinical application of Jinlida granules guided by collateral disease theory. The audience brought a wonderful academic feast. This article
There is no scientific basis for proper drinking to protect cardiovascular system

 Time of Update: 2021-04-19

Since few women drink alcohol and the correlation between genotype and alcohol intake is not very strong, no association has been observed between drinking and blood pressure, stroke or myocardial infarction.
Roche's Tecentriq first-line treatment of patients with metastatic NSCLC receives positive review from the European Union

 Time of Update: 2021-04-19

as the full details of the approval. >If approved, Tecentriq will provide a new treatment plan that will not produce chemotherapy-related adverse reactions. This is also the first and only
JAMA: The protective effect of vaccines against key mutations of the new coronavirus is much higher than that of natural infections

 Time of Update: 2021-04-19

virus strain, was modified from the laboratory and contains mutations in the key receptor binding domain of the S protein of multiple emerging mutant strains. >The research team conducted a live virus
Analyzing the risk of cardiovascular disease from a genetic perspective (1): From the liver to the heart

 Time of Update: 2021-04-19

If a person carries a risk gene, it will generally be reflected from three blood test indicators, which are: 1) low-density cholesterol (LDL-C); 2) high-density cholesterol (HDL-C); 3) lipoprotein a (Lp(a)).
Bairen Medical: Application for registration of non-stent bioprosthesis and valved pipeline products has been accepted

 Time of Update: 2021-04-19

On March 29, Bairen Medical announced that the company's product under development-stent-free bioprosthesis and valved pipeline product, submitted its registration application and was officially accepted by the National Medical Products Administration.
BridGene, a small molecule drug developed for the "unable to drug" target, reached a cooperation with Takeda

 Time of Update: 2021-04-19

new drug discovery projects, using BridGene's proprietary IMTAC chemical proteomics platform to discover new targets and small molecule drug candidates for Takeda, and Takeda will advance these drug candidates into the clinical development stage
Some children with epilepsy can be cured and early intervention is better

 Time of Update: 2021-04-19

In addition to drug development, eliminating public discrimination against patients with epilepsy is also particularly important for the treatment of the disease.
The first CAR-T therapy targeting BCMA was approved by the FDA for marketing

 Time of Update: 2021-04-19

The study recruited 127 patients with relapsed/refractory multiple myeloma who had previously received at least third-line treatment including immunomodulators, proteasome inhibitors, and anti-CD38 antibodies.
The domestically-made cervical cancer vaccine is listed at only half of the imported adults and only costs about 1,000 yuan for the entire injection.

 Time of Update: 2021-04-19

>The manufacturer of this domestic HPV vaccine is Xiamen Wantai Canghai Biotechnology Co. , Ltd. , and its trade name is "Xinkening". The instructions show that the 9 to 14-year-old vaccinators only need to vaccinate twice

Plant Extracts News

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Plant Extraction Expert Chen Chong Chinese Medicine Science Plant Extraction Leads the Innovation and Development of the Health Industry

 Time of Update: 2021-04-18

He has authored books such as "Plant Chemical Technology", "Traditional Chinese Medicine Extract Identification and Quality Standard Reference", and research and development achievements occupy half of my country's plant extract industry.
Virus-Induced Gene Silencing in Plant Roots

 Time of Update: 2021-03-16

Several virus-based vectors have been developed for use in VIGS. This chapter describes a protocol for the use of TRV vector to silence genes in roots.
A

 Time of Update: 2021-03-16

Clinical manifestations are at the beginning of the toe, nails at the far end, side edge, sometimes in the half-moon shape color change, deformation, loss of luster.
Capillary Electrophoresis with Detection by Laser-Induced Fluorescence

 Time of Update: 2021-03-16

Here, we describe the instrumentation we use and the methods for attaching fluorescent labels to oligosaccharides so that they can be detected.
Nested PCR and RFLP Analysis Based on the 16S rRNA Gene

 Time of Update: 2021-03-16

Current phytoplasma detection and identification methods are primarily based on nested polymerase chain reaction followed by restriction fragment length polymorphism analysis and gel electrophoresis.
The significance, principle and basic of experimental design

 Time of Update: 2021-03-16

Avoid the experimental design does not seriously consider, after the experiment to take the numbers to find statistical methods.
The flow of energy in an ecosystem

 Time of Update: 2021-03-16

. But the relationship between feeding and feeding between organisms in ecosystems is complex, and this connection is like an invisible web that includes all living things, so that they have some direct or indirect relationship with each other, namely
DoseResponse to and Systemic Movement of Dexamethasone in the GVG-Inducible Transgene System in Arabidopsis

 Time of Update: 2021-03-16

We have developed Arabidopsis plants using this inducible system to drive expression of a bacterial type III effector protein.
Double-Strand Break-Induced Targeted Mutagenesis in Plants

 Time of Update: 2021-03-16

It has become feasible to introduce double-strand breaks at specific chromosomal loci by using dedicated, redesigned endonucleases with altered DNA-binding specificities.
Polytrichum Commune

 Time of Update: 2021-03-16

　　In acidic and moist conifer woodlands, this species grows in large areas and is often mixed with gray or white-haired plants.

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Microbiology News

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Genome Research | Bai Fengyan's team reveals the molecular mechanism of hybrid vigor in Saccharomyces cerevisiae

 Time of Update: 2021-04-19

/>120. abstract Platemaker: 11 References 1. Schnable PS, Springer NM. 2013. Progress toward understanding heterosis in crop plants. Annu Rev Plant Biol 64: 71-88. 2. Goff SA. 2011
The research found: To use "wisdom" to defeat loneliness, you may need a "good heart"...

 Time of Update: 2021-04-19

Although the results of this study found a connection between the two, the researchers said that they still don't know what causes the connection between wisdom, loneliness, and gut microbial diversity.
Bai Fengyan's team from the Institute of Microbiology, Chinese Academy of Sciences reveals the molecular mechanism of Saccharomyces cerevisiae hybrid vigor

 Time of Update: 2021-04-19

>The fermentation and stress resistance of the domesticated population have been significantly improved, indicating that the domesticated population may have originated from heterozygous ancestors formed by the hybridization of wild strains, thus obtaining
Nat Methods | Fang Gang's team developed a new method to detect DNA methylation of a variety of bacteria, helping bacterial epigenetics research and flora analysis

 Time of Update: 2021-04-19

XS, Davis-Richardson A, Canepa R, Triplett EW, Faith JJ, Sebra R, Schadt EE & Fang G,Metagenomic binning and association of plasmids with bacterial host genomes using DNA methylation, Nature Biotechnology, 10. 1038/nbt. 4037
Nat Rev Microbiol Review | Liang Guanxiang and others summarize the development of human viromics in the past 20 years

 Time of Update: 2021-04-18

at the University of Pennsylvania School of Medicine for postdoctoral training. During the postdoctoral period, he was mainly engaged in the research of human virus and metagenomic bioinformatics. Dr. <br
Hu Ronggui/Deng Qiang/Zhang Jiming/Xu Ping collaborate to reveal a new self-limiting mechanism of hepatitis B virus

 Time of Update: 2021-04-18

Reprinting is prohibited without permission, and the author owns all legal rights.
A team of scientists discovered the new metabolic ability of gut bacteria and explained the source of hydrogen sulfide

 Time of Update: 2021-04-16

An international team of scientists led by microbiologist Professor Alexander Loy of the University of Vienna and Professor David Schleheck of the University of Konstanz discovered the new metabolic capacity of gut bacteria.
Cultivate "bacteria" for health

 Time of Update: 2021-04-16

Some of the reprinted articles on this site are not original, and the copyright and liability belong to the original author.
Gastrointestinal rejuvenation first abstain from bad diet

 Time of Update: 2021-04-16

Some of the reprinted articles on this site are not original, and the copyright and liability belong to the original author.
Cell: Fu Jingyuan's team developed a high-precision algorithm for intestinal microbial fingerprinting

 Time of Update: 2021-04-16

and chronic kidney disease such as urotoxin and thiamine (Figure 3) . It is worth noting that 22. 6% of the flora-metabolite association is found in the genetic composition variation of Blautia wexlerae, and these variation

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Amino Acids Research

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The importance and physiological role of arginine in broilers

 Time of Update: 2021-03-25

Arginine is an essential amino acid for broilersXDu China Feed Industry Information Network-Based on feed, serving animal husbandry　　For poultry, due to the lack of carbamoyl phosphate synthase in the body, it cannot synthesize arginine by itself.
Evonik announces force majeure for methionine production at Antwerp site

 Time of Update: 2021-03-25

6Ec China Feed Industry Information Network-Based on feed, serving animal husbandry　　Evonik is actively seeking a repair plan, and it is expected that the above-mentioned problems will be resolved soon.
Good news comes out frequently, and the methionine market continues to rise

 Time of Update: 2021-03-25

　　Recently, news of methionine Lido frequently came out. <br
As costs rose and the maintenance season approached, lysine manufacturers raised prices slightly.

 Time of Update: 2020-10-10

Due to the rise in raw corn, cost pressure is greater, recently lysine manufacturers slightly increased the price, this week Yip 98 content lysine quoted 7.25 yuan / kg, flat compared to the previous time, 70% lysine quoted 4.45 yuan / kg, 0.05 yuan
Soybean meal market is strong, the medium and long lines are still empty.

 Time of Update: 2020-07-30

light, with more room for soybean meal downwards. Overall, this network recommends quantitative and prudent procurement, should not be too chasing up; iq5 after the market forecast iq5 at present
The difficulty of oil price reform.

 Time of Update: 2020-07-30

to $5,520. Add in the 8% zero difference allowed by the state, the price per ton of terminal gasoline is 6460 yuan, diesel is 5960 yuan. After apportionment, the average price per litre of petrol will rise by between 4 and 5 cents. price
Northeast corn supply reduction late increase still depends on demand.

 Time of Update: 2020-07-30

affecting the may market trend, the market's concern about the future decline in the flow of grain sources has been reflected. By the cost of traders support, less surplus grain, the gradual recovery of the impact of the aquaculture industry
2009 National Forum on New Technologies for amino acid applications.

 Time of Update: 2020-07-30

letter distinguished guests: 2009 with the deepening impact of the global financial crisis on the real economy, some enterprises in China, especially export-oriented export enterprises are under-employed
Win-create methionine price increase, Hijie stopped reporting.

 Time of Update: 2020-07-30

AMb May 17, Evonik Group said the price of methionine increased to 31 yuan / kg, compared with the previous price increase of 1 yuan / kg; .
Plum Bio's net profit for the first quarter increased by 37.84% YoY

 Time of Update: 2020-07-30

On April 30, Meihua Bio released its first quarter 2019 report and business data announcement, showing that during the reporting period, the company achieved operating income of 3.338 billion yuan, an increase of 4.11% YoY, and net profit

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Natural Products News

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New discovery!

 Time of Update: 2021-03-27

1038/s41598- 021-83757-1 Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome Sci Rep【2】com/news/2021-03-green-tea-supplements-modulate-facial.
How much pesticide use in an area will affect the health of the local fetus?

 Time of Update: 2021-03-25

Researchers evaluated a large data set derived from the San Joaquin Valley in California and found a small target group that is expected to benefit from measures aimed at reducing pesticide-related birth abnormalities.
Many important achievements interpret the new progress in the field of malaria research!

 Time of Update: 2021-03-24

1038/s41467-020-17781-6Recently, in a research report published in the international journal Nature Communications, scientists from the Australian National University and other institutions have developed a new type of therapy to treat drug-resistant malaria.
PNAS interpretation!

 Time of Update: 2021-03-24

specific antibodies. B cells can also be plasma cells, whose role is to secrete a large number of antibodies, and they can also be memory cells, which are generated in the germinal center after
Multiple articles focus on new advances in the field of dementia research by scientists!

 Time of Update: 2021-03-24

style="TEXT-ALIGN: center">Image source: CC0 Public Domain><font style="vertical-align
A study by the Sun Yat-Sen University Academy of Sciences found that: a small molecule traditional Chinese medicine, Acoladine, down-regulates the production and activation of hepatocarcinoma myeloid-derived immunosuppressive cells (MDSC)

 Time of Update: 2021-03-24

These findings reveal that Akoladine reduces the production and activation of MDSC by down-regulating the extramedullary hematopoiesis of the spleen, which is one of its immunomodulatory and anti-tumor mechanisms.
Research published the latest research results on the antidepressant effects of Cistanche Tubula

 Time of Update: 2021-03-23

the guidance of the traditional effects of Cistanche, the in-depth exploration of the new effects and uses of Cistanche has important guiding significance for the large-scale cultivation of Cistanche and the development of its industry. <font
Heliyon: The compound sesaminol in the shell of sesame seeds may prevent the occurrence of Parkinson's disease in the population by activating special signaling pathways!

 Time of Update: 2021-03-23

seeds, sesame Sesaminol may protect the body against Parkinson's disease by preventing neurological damage that reduces dopamine production; in vitro experiments researchers have revealed how sesaminol can be processed by regulating the production
Science: How does phenazine, a special antibiotic produced by bacteria enhance its access to phosphorus?

 Time of Update: 2021-03-22

;">Researcher McRose said that now we know that the "antibiotics" (phenazines) produced by these pseudomonas can kill competitors, but what we want to answer is whether the phenazines produced by organisms have other functions or benefits?
One-pot glycosylation reaction sugar assembly strategy research progresses

 Time of Update: 2021-03-22

com/tags/%E7%B3%96%E5%B0%BF%E7%97%85/">diabetesRecently, this research group reported for the first time a new sugar assembly strategy for both oxoside and nucleoside based on glycosylation PVB in one-pot glycosylation reaction; using this new sugar assembly strategy, the nucleoside bioon.

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Peptide News

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What effect does small molecule peptide have to the eye?

 Time of Update: 2019-08-13

When the content of collagen peptide in the eyeball decreases, the fiber ages and collapses, the cornea will become turbid and cataract and other eye diseases will begin to occur.
What is peptide? Definition and classification of peptides

 Time of Update: 2019-08-13

Amino acids, as the basic unit of peptide, determine the complex biological structure and function of peptides due to their different kinds, numbers and order.
Why is peptide known as the source of life?

 Time of Update: 2019-08-13

With its command and regulation, it can ensure the normal growth of various tissues of life 。 After scientific measurement, the collagen content in the newborn's skin is as high as 90%, so the cells are full and elastic.
Knowledge Popularization: what is active peptide?

 Time of Update: 2019-08-13

The active peptide mainly controls the growth, development, immune regulation and metabolism of human body.
Modulatory effect of small molecule active peptide on arteriosclerosis

 Time of Update: 2019-08-12

Hyperlipidemia: the amount of fat in the blood is too high, which is easy to deposit on the inner wall of the blood vessels to form plaque, resulting in arteriosclerosis and stenosis.
Do you want to extend your life by 40%, explain the source and development of small molecular peptides

 Time of Update: 2019-08-12

That is to say, in 1927, scientists have found 35 kinds of active peptides in the gastrointestinal tract of human body, and the research on the structure and function of peptides is more and more in-depth.
The function of small molecule peptide and the "salvation" of chronic diseases

 Time of Update: 2019-08-12

In the long run, the origin of our life, cells, will continue to be damaged, and then cause various chronic diseases.
The function of small protein peptide

 Time of Update: 2019-08-12

Finally, they are world-renowned scientists and HIV prevention experts Dr. he Daying has found a synthetic amino acid chain, which is a small molecule peptide, to successfully prevent the invasion of SARS virus to human body.
Peptide is so good, why not sell it in hospital?

 Time of Update: 2019-08-12

One of the most effective ways to improve the immune ability is to eat high-quality health food, rather than by taking medicine, injection and infusion.
How to choose small molecule peptide? Who is suitable for small molecule peptide

 Time of Update: 2019-08-12

enzymolysis technology 3、 Production process 4、 Molecular size and peptide content 1、 Selection of raw materials: There are many peptides in the market.

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Studies have found that acetaldehyde dehydrogenase 2 regulates liver cholesterol metabolism

 Time of Update: 2021-03-27

-align: justify;">Redox Biology published online the latest research results of Acetaldehyde Dehydrogenase 2 Regulates HMG-CoA Reductase
Highly active pyrite nanoenzymes and their self-catalyzed anti-tumor research progress

 Time of Update: 2021-03-27

;">The application of nanozymes in tumor therapy currently faces the following two problems: one is how to increase the affinity of nanozymes with the substrate H2O2; the other is how to increase <font style="vertical-align: inherit
Progress in the asymmetric synthesis of N-substituted-α-amino acid esters

 Time of Update: 2021-03-23

com/tags/%E5%B7%A5%E4%B8%9A%E7%94%9F%E7%89%A9%E6%8A%80%E6%9C%AF/">Industrial BiotechnologyThe research work is supported by the National Key Research and Development Program, the China Scholarship Council, the Chinese Academy of Sciences Youth Innovation Promotion Association, the British bioon.
Significant progress has been made in the study of the catalytic reaction mechanism of non-heme ferrous dioxygenase (NicX)

 Time of Update: 2021-03-23

com/tags/%E4%B8%AD%E9%97%B4%E4%BD%93/" target="_blank">IntermediateThis study analyzed the structure of the NicX monomer and the complex structure of NicX with the small molecule substrate DHP and the product NFM.
Progress was made in the study of simulated natural enzymes using short peptide molecular multi-stage assembly

 Time of Update: 2021-02-24

recently, the researchers obtained a chain-like multi-stage ordered structure short peptide assembly by dynamic co-price bond assembly, combined with metal ion mating.
Advances have been made in the study of in vitro polyenzyme system catalytic synthesis of amino glucose

 Time of Update: 2021-02-24

for ammonia continues to rise. traditional method of producing ammonia, the crustacean hydrolysis method is seriously polluted and easy to cause allergic reactions, and the fermentation method causes the fermentation product to be acetaminophen due
Progress has been made in the study of γ-δ-endamide in the synth asymmetric synthesis of two-handed sex centers

 Time of Update: 2021-02-24

ester is also used in a small number of applications, but this method can only form a hand center, how to accurately construct an efficient high-stereoscopic selective multi-hand center by enzymatic method, to obtain a single configuration of γ-or δ
Progress has been made in the transformation of enzyme stereoscopic preference and its application

 Time of Update: 2021-02-24

by replacing the positions of the two amino acid residues, the three-dimensional preference of the enzyme on the hydrolytic reaction of 3-iso-butyl diazole is realized.
The study was the first to find natural (R)-styrene monooxygenase

 Time of Update: 2021-02-23

a unique branch of (R)-SMO, including eight active new (R)-SMOs, and studied three of these enzymes: SeStyA (from Streptomyces exfoliatus), AaStyA (from Amycolatopsis albispora) and Pbsdonocardiaa.com. found that they were able to catalytic
The study revealed the effects of milder drought on the microbial process of the soil at the bottom of high-cold grasslands

 Time of Update: 2021-02-10

that the degradation of organic matter and new carbon sequestration in the surface and underlying soils of high-cold grasslands have different responses to moderate drought. , the effects of milder droughts on the microbial carbon processes in the underlying soil

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Chinese Herbs Uses

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The use and function of Aconitum

 Time of Update: 2020-04-03

Many varieties of Aconitum used in traditional Chinese medicine can only be used as medicine after processing.
What is rattan?

 Time of Update: 2020-04-03

In a large number of animal based experiments, it was found that Garcinia canifera can reduce food intake by suppressing appetite, so it has the effect of reducing weight.
Can flaxseed reduce blood pressure?

 Time of Update: 2020-04-03

The results showed that the more people ate linolenic acid, the lower the risk of hypertension.
The health benefits of Pueraria

 Time of Update: 2020-04-03

Kudzu like vines can be used to make baskets, while leaves can be used for food or medicine to treat diseases.
What is lentinan?

 Time of Update: 2020-04-03

It has been reported that there are some side effects in the intravenous injection of lentinan extract.
The benefits of eating garlic!

 Time of Update: 2020-04-03

In addition, garlic has the effect of increasing insulin levels in the blood, so it can help control diabetes.
Side effects of Hawthorn

 Time of Update: 2020-04-03

The anti-aging effect of this herb comes from antioxidants called bioflavonoids.
What is the harm of senna leaf tea?

 Time of Update: 2020-04-03

As senna leaf can stimulate defecation, tea containing this herbal medicine may cause gastrointestinal side effects.
What is the use of Geranium oil?

 Time of Update: 2020-04-03

Geranium oil also has nourishing and diuretic effects, which can be used to strengthen the body and eliminate toxins.
The influence of excessive black tea

 Time of Update: 2020-04-03

Therefore, although it's OK for adults to drink black tea, too much will bring adverse effects on their health.

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