What did the Balchem-sponsored study find about Optifolin+'s effect on DNA methylation and SAM levels?

The study found that Optifolin+ significantly enhances cellular methylation capacity and DNA methylation in a human cell model, increasing S-adenosylmethionine (SAM) by 71% and enhancing cellular DNA methylation by up to 14 times.

How does the University of Arkansas–led research link Optifolin+ to healthy aging and one-carbon metabolism?

The research provides mechanistic evidence for Optifolin+'s epigenetic activity—specifically its choline-enriched L-5-MTHF composition—and links it to healthy aging and one-carbon metabolism formulations through its demonstrated ability to boost DNA methylation and SAM production.

Balchem Study Shows Optifolin+ Boosts DNA Methylation, Linking to Healthy Aging

Sep 10, 2026

Balchem announced research from the University of Arkansas showing Optifolin+ significantly enhances cellular DNA methylation and SAM levels. These findings support the ingredient's role in epigenetic regulation and healthy aging formulations.

Nutraceutical Business Review

2026-09-10

Balchem Study Shows Optifolin+ Boosts DNA Methylation, Linking to Healthy Aging

Balchem Study Shows Optifolin+ Boosts DNA Methylation, Linking to Healthy Aging

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