DuPont (a DuPont affiliate) ion exchange resins and macroporous adsorption resins

【Answer 1】 No. Model Name Product Features and Applications 1 IMAC HP1110Na Gel-type strong-acid styrene-based resin Manufactured without using ethylene dichloride; especially suitable for drinking water, food, and fruit juice production. 2 IMAC HP333 Macroporous weak-acid acrylic-based resin High exchange capacity and low volume change; suitable for removing carbonate hardness from water, and for improving water taste by removing heavy metals and chlorides. 3 IMAC HP336 Macroporous weak-acid acrylic-based resin High exchange capacity and low volume change; suitable for alkalinity removal from drinking water and water treatment in the food industry. 4 IMAC HP555 Macroporous strong-base styrene-based resin High exchange capacity; suitable for nitrate removal from water. 5 IMAC HP661 Macroporous weak-base styrene-based resin High exchange capacity; suitable for preparing de-salted water in the food industry. 6 AMBERLITE SR1LNa Gel-type strong-acid cation exchange resin Suitable for softening drinking water and water used in food production. VI. Introduction to DOWEX Series Resins No. Model Name Product Features and Applications 1 DOWEX MARATHON C Strong-acid cation exchange resin Uniform-particle gel-type ion exchange resin for industrial water softening. 2 DOWEX HCR & HCR-S/S Strong-acid cation exchange resin Conventional gel-type ion exchange resin for domestic water softening. 3 DOWEX MARATHON MSC Strong-acid cation exchange resin Uniform-particle macroporous ion exchange resin for high-oxidizing conditions. 4 DOWEX MAC-3 Weak-acid cation exchange resin Alkalinity and salt removal. 5 DOWEX MARATHON WBA Weak-base anion exchange resin Macroporous uniform-particle resin with high exchange capacity and high exchange rate; suitable for high-flow-rate systems. 6 DOWEX MARATHON A Strong-base anion exchange resin High-capacity, high-efficiency uniform-particle gel-type resin for anion beds or mixed beds. 7 DOWEX MONOSPHERE 650C Strong-acid cation exchange resin Premium-grade resin for condensate polishing. 8 DOWEX MONOSPHERE 550A Strong-base anion exchange resin Premium-grade resin for condensate polishing. 9

A century-old legacy — the secret role of resins in biopharmaceuticals

【Answer 2】 Gazing across the globe, the world has undergone dramatic transformations. Rohm and Haas Company (now DuPont Water Solutions) has been manufacturing resin products for over eight decades. In the 1990s, as the inventor and technological leader in ion exchange resins, Rohm and Haas Company (now DuPont Water Solutions) introduced the world’s most advanced adsorption–decolorization ion exchange resin technology into China. It was precisely this resin technology that laid the foundation for the rapid development of China’s antibiotic industry—enabling domestic production of antibiotics (e.g., cephalosporins, erythromycin) to reach world-leading levels. Concurrently, Rohm and Haas and Dow (now DuPont Water Solutions) ion exchange resins demonstrated superior adsorption capacity and strength in amino acid (e.g., lysine) extraction, significantly enhancing production efficiency at Chinese amino acid manufacturers. At the dawn of the 21st century, Rohm and Haas Company (now DuPont Water Solutions) pioneered the introduction of acrylic-based macroporous strong-base anion exchange resin technology tailored to heparin extraction processes—greatly improving both heparin recovery potency and regeneration efficiency. Resin products specially developed for vitamin B12 production likewise markedly enhanced extraction efficiency and purity. Today, DuPont Water Solutions’ resin products continue to enjoy broad application across the biopharmaceutical sector. Biopharmaceutical molecule production comprises two stages: Upstream processing: involving microbial fermentation or chemical synthesis. Downstream processing: aimed at capturing, separating, purifying, and polishing target proteins, peptides, or active molecules. As the global market leader in ion exchange resins, we offer a wide range of resin products based on hydrophobic (polystyrene–divinylbenzene) or moderately hydrophilic (polyacrylic) matrices—specifically engineered for downstream separation and purification of small-molecule bioproducts such as peptides, oligonucleotides, antibiotics, and natural extracts. Peptides Peptides can be produced either via chemical synthesis (solid-phase or liquid-phase) or through recombinant gene expression. In both cases, polymeric adsorption resins (e.g., AMBERCHROM™ CG and XT series) are applicable in capture and polishing steps. Compared with silica-based chromatography media, AMBERCHROM™ products offer distinct advantages: they permit in-place cleaning and sterilization using caustic soda (1 M NaOH at 60°C). This enables thorough cleaning and sterilization of production equipment—preventing product carryover as well as contamination by endotoxins or viruses. AMBERCHROM™ products remain stable in any solvent across the full pH range and exhibit outstanding mechanical stability. This, in turn, allows manufacturers to produce certain products more efficiently, economically, and with lower environmental impact. Oligonucleotides Oligonucleotides are DNA or RNA polymers used as probes for DNA or RNA detection in research, gene therapy, molecular diagnostics, and forensic science. They can be synthesized chemically or enzymatically. AMBERCHROM™ resins can be applied to purify liposome-conjugated oligonucleotides and PEGylated aptamers. Antibiotics Antibiotics are drugs used to prevent or treat bacterial infections.

DuPont de Nemours, Inc. (DD) Launches AmberChrom SIL for Peptide Purification

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DuPont de Nemours launched AmberChrom SIL silica gel chromatography media in C8 and C18 chemistries for peptide purification. This expansion targets rising demand in the GLP-1 market to enhance manufacturing scalability.

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DuPont de Nemours, Inc. (DD) Launches AmberChrom SIL for Peptide Purification

DuPont de Nemours, Inc. (DD) Launches AmberChrom SIL for Peptide Purification

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