 Home > Active Ingredient News >

Digestive System Information

J Hepatol (IF=25) Significant progress!

 Time of Update: 2021-10-21

1 1 2 2 tetrachloroethane 1 2 ethanediol 1 bromopropane 1 heptanol 1 propanamine

Dopamine receptor D2 (DRD2) antagonism selectively blocks YAP in macrophages and prevents liver fibrosis in rodents and large animal models, showing the potential of GPCR-based NASH therapy .
Can coffee reduce the risk of liver cirrhosis?

 Time of Update: 2021-10-21

1 2 dibromo 1 2 diphenylethane 1 3 dichloropropene 1 3 dioxolane 1 heptanol 1 propanamine

Subjects with coffee or tea intake> 3 cups have a lower risk of LSM ≥ 9.
How to choose a gastrointestinal motility drug for functional dyspepsia?

 Time of Update: 2021-10-21

1 2 dibromo 1 2 diphenylethane 1 3 dichloropropene 1 3 dioxolane 1 heptanol 1 propanamine

■Prescription 1 domperidone tablet 10mg, 3 times a day, orally half an hour before meals. Indications: Patients with abdominal fullness and early satiety symptoms above FD <br
TAF can improve liver reserve and glomerular filtration rate in patients with hepatitis B cirrhosis after TIPS treatment

 Time of Update: 2021-10-21

1 2 dibromo 1 2 diphenylethane 1 3 dichloropropene 1 3 dioxolane 1 heptanol 1 propanamine

The study found that, 24 months after TIPS, compared with entecavir (ETV) and tenofovir disoproxil fumarate (TDF), tenofovir fumarate (TAF) improved liver reserve function and estimated renal small Sphere filtration rate (eGFR) has significant advantages [5] .
What is the effect of changing to propofol tenofovir for patients with poor response to nucleoside treatment?

 Time of Update: 2021-10-21

1 2 dibromo 1 2 diphenylethane 1 3 dichloropropene 1 3 dioxolane 1 heptanol 1 propanamine

2. A univariate analysis of the efficacy of TAF and previous TDF response showed that in the entire cohort, poor response to previous TDF treatment was significantly associated with a lower MVR rate (OR 0.
Repeated vomiting blood and black stool for several days, but the hemostatic drugs are ineffective...Where is the bleeding?

 Time of Update: 2021-10-21

1 2 dibromo 1 2 diphenylethane 1 3 dichloropropene 1 3 dioxolane 1 heptanol 1 propanamine

Multiple ulcers in the duodenal bulb (stage S2) (combined with the patient's medical history, considering the possibility of bleeding in the upper and middle small intestines, further examination is recommended) .
You can have both fish and bear paws!

 Time of Update: 2021-10-21

1 2 dibromo 1 2 diphenylethane 1 3 dichloropropene 1 3 dioxolane 1 heptanol 1 propanamine

, and velizumab was maintained at every 8 weeks after induction therapy at 0, 2 and 6 weeks (intravenous injection of 300 mg) . In July 2021, the colonoscopy was rechecked after 14
Express aims to functionally cure hepatitis B, and antisense oligonucleotide therapy enters the clinic

 Time of Update: 2021-10-21

1 1 2 2 tetrachloroethane 1 2 ethanediol 1 bromopropane 1 heptanol 1 propanamine

▎Editor of WuXi AppTec content team On October 11, 2021, Aligos Therapeutics announced that ALG-020572 has completed the first patient administration in phase 1 clinical trial .
The effect of fully automatic magnetically controlled capsule gastroscopy is comparable to that of traditional gastroscopy, and the results of the Xinqiao Hospital team published the "Lancet" sub-journal

 Time of Update: 2021-10-21

1 2 dibromo 1 2 diphenylethane 1 2 ethanediol 1 bromopropane 1 heptanol 1 propanamine

, and the results of the two examinations were compared . The primary endpoint of the study was the complete detection rate of FAMCE on the anatomical structures of the stomach (cardia, fundus
Courier's stimulating antibody level is 3.5 to 7.5 times that of the approved vaccine, and the results of phase 3 clinical trials of the new hepatitis B vaccine are released

 Time of Update: 2021-10-21

1 1 2 2 tetrachloroethane 1 3 dichloropropene 1 3 dioxolane 1 heptanol 1 propanamine

▎Editor of WuXi AppTec's content team On October 13, 2021, VBI Vaccines announced that it is investigating the third-generation 3 hepatitis B virus (HBV) candidate vaccine Sci-B-Vac, which is being tested in 18-45-year-old adults.
Cell Discovery │ He Ming/Zhao Qian from Shanghai Jiaotong University reveals new mechanisms and therapeutic targets for alcoholic liver disease

 Time of Update: 2021-10-21

2 2 dimethylbutane 2 methoxyethanol 2 methyltetrahydrofuran 293t cells 7 methylguanosine

On October 12, 2021, He Ming and Zhao Qian from Shanghai Jiaotong University jointly published a research paper entitled "SIRT2-mediated deacetylation and deubiquitination of C/EBPβ prevents ethanol-induced liver injury" in Cell Discovery (IF=10.
One table and one picture: Summary of high scores in the diagnosis and management of chronic abdominal distension

 Time of Update: 2021-10-21

1 1 2 2 tetrachloroethane 1 2 ethanediol 1 bromopropane 1 heptanol 1 propanamine

: fermentable Sugars, disaccharides, monosaccharides and polyols; HBT: Hydrogen Breath Test Summary Abdominal bloating and abdominal bulging are very common symptoms, which can have a negative impact on patients suffering from a series of basic medical
Walk into AOCC, pay attention to the new progress of IBD interleukin therapy

 Time of Update: 2021-10-21

1 2 dibromo 1 2 diphenylethane 1 3 dichloropropene 1 3 dioxolane 1 heptanol 1 propanamine

/> N Engl J Med 2016;375:1946 -60. Statement: This content is only for Chinese medical and health professionals, and aims to provide scientific information to and only to medical and health professionals for personal learning and reference
GUT: Does Sofosbuvir/Vipatavir combined with low-dose ribavirin benefit patients with hepatitis C and renal impairment?

 Time of Update: 2021-10-20

1 1 2 2 tetrachloroethane 1 2 ethanediol 1 4 dichlorobenzene 1 4 cyclohexadiene 1 methoxybutane

At present, regarding the effects of sofosbuvir/velpatasvir (sofosbuvir/velpatasvir, SOF/VEL) combined or not combined with low-dose ribavirin (RBV) on chronic hepatitis C virus (HCV) infection and severe renal damage ( RI) Patients have limited real-world effectiveness and safety data .
JGH: Simple Endoscopy Score for Crohn's Disease (CD-SES) in Predicting the Outcome of Crohn's Disease

 Time of Update: 2021-10-20

1 4 dichlorobenzene 1 4 cyclohexadiene 1 methoxybutane 1 propanamine 4 hydroxyacetophenone

Therefore, this study aims to evaluate the postoperative outcome based on the location of the disease and verify the ability of the Simple Endoscopic Score (SES-CD) of CD to predict the disease .
TRANSL PSYCHIAT: Does this medicine have a laxative effect and is "rejuvenating"?

 Time of Update: 2021-10-20

1 1 2 2 tetrachloroethane 1 2 ethanediol 1 bromopropane 1 4 cyclohexadiene 1 methoxybutane

In the post-scan recall task, the procapride group was more accurate than the placebo group in distinguishing the target image (novelty + familiarity) from the distractor (F(1,38) = 5.
J Gastroenterology: Analysis of mortality and risk factors in patients with inflammatory bowel disease caused by arteriovenous thromboembolism

 Time of Update: 2021-10-20

1 1 2 2 tetrachloroethane 1 2 ethanediol 1 bromopropane 1 methoxybutane 1 propanamine

27 times that of non-IBD controls, and there is no large-scale national research report on the TE-related severity of IBD patients and the incidence of death and risk factors in Asian countries.
JGH: The impact of splenectomy on the prognosis of patients undergoing jugular intrahepatic portosystemic shunt

 Time of Update: 2021-10-20

1 2 dibromo 1 2 diphenylethane 1 2 ethanediol 1 3 dioxolane 1 methoxybutane 2 2 bipyridine

> Portal hypertension (PHT) is a pathological phenomenon in which the portal pressure gradient exceeds 5 mmHg, and it is also a progressive complication of liver cirrhosis
AP&T: Young people still have a higher risk of upper gastrointestinal bleeding after Helicobacter pylori eradication than healthy people

 Time of Update: 2021-10-20

1 1 2 2 tetrachloroethane 1 2 ethanediol 1 bromopropane 1 methoxybutane 2 2 bipyridine

Patients with Helicobacter pylori eradicated have an increased risk of UGIB after the first 2 years of follow-up (HR: 2.
Nat Med: Analysis of the efficacy of Aramchol in the treatment of non-alcoholic steatohepatitis

 Time of Update: 2021-10-20

1 1 2 2 tetrachloroethane 1 2 ethanediol 1 bromopropane 1 4 cyclohexadiene 1 methoxybutane

Aramchol in patients with nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled phase 2b trial .

Go to Page

Digestive System Information

J Hepatol (IF=25) Significant progress!

Can coffee reduce the risk of liver cirrhosis?

How to choose a gastrointestinal motility drug for functional dyspepsia?

TAF can improve liver reserve and glomerular filtration rate in patients with hepatitis B cirrhosis after TIPS treatment

What is the effect of changing to propofol tenofovir for patients with poor response to nucleoside treatment?

Repeated vomiting blood and black stool for several days, but the hemostatic drugs are ineffective...Where is the bleeding?

You can have both fish and bear paws!

Express aims to functionally cure hepatitis B, and antisense oligonucleotide therapy enters the clinic

The effect of fully automatic magnetically controlled capsule gastroscopy is comparable to that of traditional gastroscopy, and the results of the Xinqiao Hospital team published the "Lancet" sub-journal

Courier's stimulating antibody level is 3.5 to 7.5 times that of the approved vaccine, and the results of phase 3 clinical trials of the new hepatitis B vaccine are released

Cell Discovery │ He Ming/Zhao Qian from Shanghai Jiaotong University reveals new mechanisms and therapeutic targets for alcoholic liver disease

One table and one picture: Summary of high scores in the diagnosis and management of chronic abdominal distension

Walk into AOCC, pay attention to the new progress of IBD interleukin therapy

GUT: Does Sofosbuvir/Vipatavir combined with low-dose ribavirin benefit patients with hepatitis C and renal impairment?

JGH: Simple Endoscopy Score for Crohn's Disease (CD-SES) in Predicting the Outcome of Crohn's Disease

TRANSL PSYCHIAT: Does this medicine have a laxative effect and is "rejuvenating"?

J Gastroenterology: Analysis of mortality and risk factors in patients with inflammatory bowel disease caused by arteriovenous thromboembolism

JGH: The impact of splenectomy on the prognosis of patients undergoing jugular intrahepatic portosystemic shunt

AP&T: Young people still have a higher risk of upper gastrointestinal bleeding after Helicobacter pylori eradication than healthy people

Nat Med: Analysis of the efficacy of Aramchol in the treatment of non-alcoholic steatohepatitis