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Construction of ionizable iron nanoadjuvants for personalized tumor vaccine treatment
Time of Update: 2023-02-03
202209910(Contributed by: Yu Navy Research Group) Tumor vaccines represent a therapeutic method that can induce body-specific and persistent anti-tumor immune response, and have great prospects for improving clinical tumor treatment.
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Progress has been made in the study of the response of carbon dioxide emissions to warming in degraded peat bogs at Chengdu Biosite
Time of Update: 2023-02-03
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Suborganelle localization, interaction, and viability fine-tuning patterns of the human complete set of mitochondrial aminoacyl-tRNA synthetases
Time of Update: 2023-02-03
TRS_Editor A{font-family:;font-size:12pt;}On December 12, the international academic journal Nucleic Acids Research published online the latest collaborative research results of Xiaolong Zhou's research group and Wang Enduo's research group of the Center for Excellence in Molecular Cell Science (Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences, "RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple.
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Li Xinzheng's research group and collaborators have made new progress in the development of simulation methods for molecular cluster tunneling cleavage spectra
Time of Update: 2023-02-03
Professor Li Xinzheng's research group, from the Institute of Condensed Matter Physics and Materials Physics, the State Key Laboratory of Artificial Microstructure and Mesoscopic Physics, the Nanopho
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Challenging past theories: Scientists have discovered a homolog of a well-known human protein in nematodes
Time of Update: 2023-02-03
Caenorhabditis elegansIn a recent study published in Nature Communications, Dr. Emily Spaulding and Dr. Dustin Updike discovered a homologue of a well-known human protein nucleolar protein in Caenorhabditis elegans, a small transparent worm.
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Nature sub-issue: Breakthrough! Sui Jianhua's team at Beijing Institute of Biological Sciences has made important progress in broad-spectrum anticancer drugs targeting CD98!
Time of Update: 2023-02-03
The results illustrate that the anti-tumor function of S1-F4 is dependent on macrophages and DCs. Further analysis revealed that CD8+ T cells also play an important role in the antitumor effect of S1-F4, and that S1-F4 therapy can induce the generation of antigen-specific long-term immune memory.
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Cell sub-journal: Zhang Haojian's team revealed the dynamic changes of m6A modification and the regulatory role and mechanism of PRMT6 in acute myeloid leukemia
Time of Update: 2023-02-03
Acute myeloid leukemia (AML) is a class of malignant hematologic tumors caused by myeloid progenitor cell differentiation and malignant proliferation. The accumulation of genetic or epigenetic change
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Nanjing Medical University, Chinese Academy of Sciences Nature issued a paper: novel ribosomes in spermatogenesis can produce sperm-specific proteome
Time of Update: 2023-02-03
On December 14, 2022, the team of Sha Jiahao and Guo Xuejiang of Nanjing Medical University and the team of Qin Yan of the Institute of Biophysics of the Chinese Academy of Sciences published the article "A male germ-cell-specific ribosome controls male fertility" in Nature, discovering a novel ribosome in spermatogenesisSTAbility to produce sperm-specific proteomes.
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There is a new method for molecular imaging detection of early gastric cancer
Time of Update: 2023-02-03
Recently, the reporter of Science and Technology Daily learned from the Xinqiao Hospital of the Army Military Medical University that Professor Yang Shiming of the Department of Gastroenterology of the hospital, the team of researcher Wang Lei of the National Center for Nanoscience and the team of academician Xing Mengqiu of the University of Manitoba in Canada designed and constructed a bipyrene-peptide nanoprobe, which effectively solved the problem of "difficult to distinguish" and "difficult to break" in early gastric cancer.
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Chinese scientists have found that intermittent fasting based on traditional Chinese medicine nutrition therapy has made nearly half of patients with type 2 diabetes say goodbye to hypoglycemic drugs
Time of Update: 2023-02-03
Recently, Liu Dongbo's team from Hunan Agricultural University and Hu Minghai's team from Central South University published the results of a clinical study in the well-known endocrinology journal "Journal of Clinical Endocrinology and Metabolism" [5], showing that compared with the control group, receiving 3 months of traditional Chinese medicine nutrition therapy (CMNT), that is, intermittent fasting with a special diet, can make more T2D patients meet the criteria for diabetes remission (glycated hemoglobin A1c [HbA1c] is less than 6.
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Why some people are unable to regain their sense of smell after getting COVID-19
Time of Update: 2023-02-03
"For the study, Goldstein and colleagues analyzed olfactory epithelial samples collected from 24 biopsies, including nine patients with long-term olfactory loss due to COVID-19.
"For the study, Goldstein and colleagues analyzed olfactory epithelial samples collected from 24 biopsies, including nine patients with long-term olfactory loss due to COVID-19.
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STTT:BA.5 causes stronger damage to cardiomyocytes than BA.1, similar to Delta
Time of Update: 2023-02-03
5 variant is more replicable, produces a more contagious virus, can cause stronger cytopathic effects, and stops heart muscle cells beating faster, or similar to Delta.
5 variant is more replicable, produces a more contagious virus, can cause stronger cytopathic effects, and stops heart muscle cells beating faster, or similar to Delta.
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Aging Cell Stress accelerates retinal degeneration, similar to natural aging
Time of Update: 2023-02-03
A new study in mice by researchers at the University of California, Irvine (UCI) shows that stress, such as elevated intraocular intraocular pressure (IOP), causes epigenetic changes in retinal tissue that resemble natural aging.
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Chenji Wang/Yao Li's team revealed the oncogenic mechanism by which SPOP gene mutations promote abnormal activation of the BRAF-dependent MAPK-ERK signaling pathway
Time of Update: 2023-02-03
Fig. 1: SPOP-mediated BRAF ubiquitination modification to regulate the pattern of MAPK-ERK signaling pathwayFeng Kai, a master's student in the School of Life Sciences (currently a doctoral student at the Institute of Phenotypic Group), and Qing Shi, a postdoctoral student, are co-first authors of the paper.
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Chinese scholars have made progress in the field of perovskite optoelectronic materials
Time of Update: 2023-02-03
Figure Perovskite thin film phase separation study. (a) Theoretical calculations based on first principles reveal the thermodynamic driving force of phase separation at the atomic/ionic scale; (b) Sc
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New software creates 3D nanostructures out of DNA to create miniature containers for delivering drugs
Time of Update: 2023-02-03
Science and Technology Daily Beijing, Dec. 27 (Reporter Zhang Mengran) According to the latest issue of Science Advances magazine, a new open-source software program developed by researchers at Duke
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National Science Review: Reveal patterns of congenous speciation
Time of Update: 2023-02-03
Based on genomic data, He Shunping's team, a researcher at the Institute of Hydrobiology, Chinese Academy of Sciences, analyzed the genetic diversity, phylogeny and genetic structure, population dynamic history, gene flow, genomic island, and selection intensity of the two naked carps, supplemented by theoretical simulations, and proposed a conspecificity or micro-parapatric speciation model.
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Nature: Damage to the father's DNA from radiation is passed on to offspring
Time of Update: 2023-02-03
Inheritance of paternal DNA damage by histone-mediated repair restriction Image: Densely packed DNA in a female.
Inheritance of paternal DNA damage by histone-mediated repair restriction Image: Densely packed DNA in a female.
Inheritance of paternal DNA damage by histone-mediated repair restriction Image: Densely packed DNA in a female.
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Major advances in the genetic factors of obesity: the discovery of a new "thinning" gene
Time of Update: 2023-02-03
Reference: Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3 The researchers caution that this finding does not mean that people with this genetic variant can overeat without gaining weight.
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Giant viruses that are difficult to study now have a new observation tool – HVEM
Time of Update: 2023-02-03
Murata said that even with a limited sample and slightly lower resolution, the researchers gathered enough information to understand the structure of the giant virus particles more clearly than ever before.