-
Double transplant successful treatment of 1 case of severe regenerative anemia
Time of Update: 2020-06-24
In order to promote stem cell implantation, avoid implant failure or adverse risk, save the patient's life, we in the patient infusion donor peripheral hematopoionstem stem cell after The next day, for patients to jointly intake a HLA type 9/10 conjoined non-blood cord blood stem cells for double transplantation?
-
Multiple myeloma in the case of the diagnosis of disease sedatives of the blood system
Time of Update: 2020-06-24
1 Case Thinking Map cases provided: Wang Wei, Wang Wei, Wang Hui II, bone marrow picture of the (1 ) (3) (4) (5) of the (5) (5) (6) (1) (2) (3) (4) 4, MM-relat
-
1 case of hyperthermia-cold hemoglobinuria patients with peripheral blood smears of granulocytes and single-core cells
Time of Update: 2020-06-24
There are many reasons for swallowing blood cells in bone marrow morphological tests, and there are more types of cells that are swallowed However, the appearance of peripheral blood medium granuloc
-
Brit J Heamatol: Primary prevention of venous thromboembolism in patients with multiple myeloma treated with immunomodulators
Time of Update: 2020-06-24
Immunomodulation drugs (IMiDs) improve survival in patients with multiple myeloma (MM) and are the cornerstone of treatment at all stages Despite good tolerance, IMiD can increase the incidence of v
-
Thorax: Lung Complications in Pregnant Women with Sickle Cell Disease
Time of Update: 2020-06-24
Sickle cell disease (SCD) is a multi-system disease characterized by the risk of vascular aphation, chronic anemia and short life span More and more SCD patients can live to the age of childbirth an
-
Blood: Potential Mechanisms of Drug Induced Bleeding
Time of Update: 2020-06-24
Drug-induced bleeding leads to higher morbidity and mortality Antithrombotic drugs, which have obvious causes for accidental bleeding, are relatively easy to control But the mechanism of bleeding di
-
Blood: Transcription Factor ATF4 Activates BCL11A Transcription to Silent Fetal Hemoglobin Expression
Time of Update: 2020-06-24
Fetal hemoglobin reactivation remains a critical goal for the treatment of patients with sickle cell disease and beta-thalassemia Previous researchers have found that fetal gamma-globin gene silenci
-
Focus on rare disease "thalassemia": FDA awards Mitapivat orphan drug title
Time of Update: 2020-06-24
Pharmaceutical company Agios announced today that the U.S Food and Drug Administration, the Administration of ( FDA ) has awarded acetone acid kinase-R (PKR) activator mitapivat for the treatment
-
Blood: Prognosis for hematopoietic cell transplantation treatment for Wiskott-Aldrich syndrome
Time of Update: 2020-06-24
Aldridge syndrome (WAS) is an X-chromosome chain disease caused by mutations in the WAS gene that can lead to platelet reduction, eczema, recurrent infections, autoimmune diseases and malignant tumo
-
Blood: A new model that evaluates Emicizumab's functionality!
Time of Update: 2020-06-24
Bispecific antibody Emicizumab (Amyzumab) is increasingly used in the treatment of haemophilia Type A However, its specificity to human factors IX and X factor (FIX, FX) limited its invivia function
-
Blood: Cytotoxic gene mutation sychagic syndrome for secondary phagocytosis
Time of Update: 2020-06-24
Phagocytophaphal syndrome (HLH) is a life-threatening high-inflammatory disease, mainly due to cytotoxic killer cells (CTL) and NK cell functional defects leading to antigen removal disorders, monon
-
Blood: Risk of bleeding in acquired haemophilia A (AHA) and response to hemostatic treatment
Time of Update: 2020-06-24
Acquired haemophilia A (AHA) is caused by autoantibodies of anticoagulant VIII (FVIII), usually accompanied by accidental bleeding Compared to congenital haemophilia, residual FVIII activity in pati
-
Blood: GPS2 promotes red differentiation by regulating EKLF protein stability
Time of Update: 2020-06-24
Red blood cell production is a complex multi-stage process that involves early erythromycin differentiation to transnuclear mature red blood cells, in which their genealogy-specific transcription fa
-
Brit J Heamatol: Statins and epoxy 2 inhibitors improve survival in patients with diffuse large B cell lymphoma
Time of Update: 2020-06-24
Preclinical data show that statins, metformin and epoxy-2 (COX-2) inhibitors have the potential to fight lymphoma In a recent study published in the journal British Journal of Haematology, researche
-
Blood: In acute lymphoblastic leukemia, E2A-PBX1 is the secondary activation factor of RUNX1
Time of Update: 2020-06-24
E2A is a basic helix-ring-helix (bHLH) transcription factor that plays a vital role in determining the fate of tissue-specific cells, including B-cell spectral differentiation In 5% of children with
-
Blood: Long-term prognosis for the treatment of acetaminotaminal co-phenyramstininin
Time of Update: 2020-06-24
Condensate disease (CAD) refers to autoimmune diseases characterized by the concentration of red blood cells in the blood vessels at the end of the limb, the occurrence of skin microcirculation diso
-
Brit J Heamatol: Prediction of hemorrhage during vitamin K antagonist treatment in venous thrombosis clinic patients
Time of Update: 2020-06-24
Bleeding is the most common complication associated with anticoagulant therapy, but its characteristics are not yet fully defined and important for risk/benefit assessment In a recent study publishe
-
NEJM: Emapalumab Treatment of Primary Phytophalymplylylymlympercell Cytomegapathy
Time of Update: 2020-06-24
Primary phage lymphocytic hyperplasia is a rare disease characterized by immune disorders and high inflammation, usually occurring in infancy, with higher mortality rates researchers examined th
-
Blood: EGFR-dependent DNA repair promotes blood regeneration
Time of Update: 2020-06-24
Chemotherapy and radiotherapy can cause DNA damage in hematopoietic stem cells (HSCs), leading to HSC depletion and dysfunction, and malignant transformation over time The external regulation of HSC
-
ULTOMIRIS (ravulizumab) treatment of atypical hemolytic uremia syndrome (aHUS): CHMP gives positive reviews
Time of Update: 2020-06-24
Alexion Pharmaceuticals recently announced that the European Medicines Agency's Human Drug Commission (CHMP) has taken a positive approach, recommending the EUROPEAN Union approval of ULTOMIRIS (rav