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NATURE: Large-scale screening, new drugs used to combat SARS-CoV-2.

 Time of Update: 2020-07-30

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noteworthy, MDL-28170, ONO 5334, and apilimod were found to be able to replicate antivirals in human iPSC-derived lung cell-like cells, and PIKfyve inhibitors also exhibited antiviral efficacy in primary human lung transplantmodels.
Immun Inflamm Dis: The functional phenotype of DENV-specific T cells is associated with the severity of dengue fever.

 Time of Update: 2020-07-29

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Although the role of DENV-specific T cells in the pathogenesis of acute dengue infection has become clear, the function of viral-specific T cells associated with less severe clinical diseases is not y
Science: Chinese scientists have structurally revealed a powerful therapeutic antibody and SARS-CoV-2 and SARS-CoV mechanisms.

 Time of Update: 2020-07-29

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According to the World Health Organization (WHO), the 2019 coronavirus epidemic (COVID-19) pandemic has infected more than 7 million people in more than 200 countries and killed 400,000 people, accord
Nat neuroscience: AHR is the host factor of the Zika virus and a candidate for antiviral therapy.

 Time of Update: 2020-07-29

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The !---- to identify host factors in the ZIKV replication process can guide effective therapeutic interventions In genome-wide transcription studies, the authors found that ZIKV infection triggered t
No most toxic only more toxic, the new crown virus of the same class of virus is still quite a lot?

 Time of Update: 2020-07-29

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!---- The global total of more than 16 million confirmed cases of new coronavirus pneumonia has become a major threat to public health in China and around the world At present, the new crown virus pne
The Revelations of the War Epidemic . . . Zhang Liyang: Transplantthets to Wuhan.

 Time of Update: 2020-07-29

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When Secretary Zhang Liyang led the second batch of medical teams from Beijing Concord Hospital to Wuhan on February 7, it was the "dark" moment of the development of the wuhan epidemic, with the numb
Lancet: Ad5 vector COVID-19 vaccine Phase II clinical success.

 Time of Update: 2020-07-29

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!---- researchers recently published the results of the Iegenic and Safe Phase II clinical study of the non-replicated type 5 adenovirus (Ad5) vector COVID-19 vaccine This random, double-blind, placeb
Why fluid dynamics is important for COVID-19 research.

 Time of Update: 2020-07-29

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The impact of respiratory infections on humans has become the focus of attention !---- The biggest defense against health crises is government policy, which is firmly rooted in science In order to cur
Nature: Mass screening found 21 existing anti-neo-coronavirus drugs!

 Time of Update: 2020-07-29

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As !---- of July 27, 2020, more than 16.25 million cases of newly confirmed pneumonia (COVID-19) have been confirmed worldwide, bringing the total number of deaths to more than 640,000 It takes 12 to
J Biol Chem: Blocking deadly cytokine storms is an important weapon in the treatment of COVID-19.

 Time of Update: 2020-07-29

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The !---- killer is not a virus, but an immune response The current pandemic is unique, not only because it is caused by a new virus that puts everyone at risk, but also because the scope of the innat
JAMA: Insights from two pairs of severely ill brothers, this gene is important for fighting the new coronavirus.

 Time of Update: 2020-07-29

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!---- The Journal of the American Medical Association (JAMA) recently published a study by a Dutch team that analyzed two pairs of young brothers with severe illness, suggesting that the TLR7 gene pla
Heart: The association between right ventricular dysfunction and poor prognosis in patients with infectious shock.

 Time of Update: 2020-07-29

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Heart muscle dysfunction (SIMD) caused by !---- sepsis can affect the left and right ventricles However, the characteristics and outcomes of simD's various manifestations are not yet clear Recently, a
J Infect Dis: Recombinant bubble-ventitis virus - immune-to-immune, heterogeneous and safety analysis of the Zaire Ebola virus envelope glycoprotein vaccine.

 Time of Update: 2020-07-29

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!---- This dual-blind study assessed the immunogenicity, batch consistency and safety of the recombinant bubbly oral itisvirus-Zaire Ebola virus-Zaire Endomeleta Vaccine (rVSV G-ZEBOV-GP) 1197 healthy
NEJM: Preclinical study of COVID-19 candidate vaccine mRNA-1273: The effect is obvious!

 Time of Update: 2020-07-29

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!---- biotech company Moderna is a pioneer in messenger RNA (mRNA) therapeutics and vaccines, and Moderna today published a preclinical study to evaluate the COVID-19 candidate vaccine mRNA-1273, the
COVID-19 candidate vaccine mRNA-1273 III clinical trial: the scale will continue to expand.

 Time of Update: 2020-07-29

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!---- Clinical Biotech company Moderna is a pioneer in messenger RNA (mRNA) therapeutics and vaccines, and Moderna today announced an additional $472 million investment in BARDA (Biomedical Advanced R
Cell Reports: The Lanfei/Xu Jianqing/Xie Youhua team worked with Ai Yuelu Yananan to find several new crown neutralizing antibodies.

 Time of Update: 2020-07-29

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Although the domestic outbreak of the new crown has been brought under control, but the outbreak is still on the rise, the world's existing nearly 5 million confirmed people, in order to continue to f
Nervous system manifestations of COVID-19 infection - hemorrhagic reversible post-encephalopathy syndrome.

 Time of Update: 2020-07-29

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The new coronavirus (COVID-19) has become popular around the world In the literature, the diagnosis and treatment of COVID-19 disease is mainly concentrated in the respiratory system, but the symptom
The patient is in critical condition, and the moment he took off his pants in the ICU, he had decided to live and die.

 Time of Update: 2020-07-29

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46-!---- year-old male patient with a fever for 3 days In their home bought a point of anti-fever medicine, the effect is not too good, or has a fever, the highest body temperature to 39.5 degrees C,
1 year, pneumonia 3 months, antibiotics can not cure?

 Time of Update: 2020-07-29

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1 Medical history profile Male, 49 years old, Jiangsu, 2018-11-06 into Zhongshan Hospital infection department main complaint: cough cough sputum 1 year, chest pain 7 months of current medical history
Sci Trans med: Australian scientists have developed new drugs to prevent cardiovascular disease with significantly reduced side effects.

 Time of Update: 2020-07-29

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!---- Every year, one-third of the world's deaths are caused by cardiovascular disease, mainly heart attacks and strokes Both diseases are caused by blood clots blocking blood vessels in the brain or

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Infection

NATURE: Large-scale screening, new drugs used to combat SARS-CoV-2.

Immun Inflamm Dis: The functional phenotype of DENV-specific T cells is associated with the severity of dengue fever.

Science: Chinese scientists have structurally revealed a powerful therapeutic antibody and SARS-CoV-2 and SARS-CoV mechanisms.

Nat neuroscience: AHR is the host factor of the Zika virus and a candidate for antiviral therapy.

No most toxic only more toxic, the new crown virus of the same class of virus is still quite a lot?

The Revelations of the War Epidemic . . . Zhang Liyang: Transplantthets to Wuhan.

Lancet: Ad5 vector COVID-19 vaccine Phase II clinical success.

Why fluid dynamics is important for COVID-19 research.

Nature: Mass screening found 21 existing anti-neo-coronavirus drugs!

J Biol Chem: Blocking deadly cytokine storms is an important weapon in the treatment of COVID-19.

JAMA: Insights from two pairs of severely ill brothers, this gene is important for fighting the new coronavirus.

Heart: The association between right ventricular dysfunction and poor prognosis in patients with infectious shock.

J Infect Dis: Recombinant bubble-ventitis virus - immune-to-immune, heterogeneous and safety analysis of the Zaire Ebola virus envelope glycoprotein vaccine.

NEJM: Preclinical study of COVID-19 candidate vaccine mRNA-1273: The effect is obvious!

COVID-19 candidate vaccine mRNA-1273 III clinical trial: the scale will continue to expand.

Cell Reports: The Lanfei/Xu Jianqing/Xie Youhua team worked with Ai Yuelu Yananan to find several new crown neutralizing antibodies.

Nervous system manifestations of COVID-19 infection - hemorrhagic reversible post-encephalopathy syndrome.

The patient is in critical condition, and the moment he took off his pants in the ICU, he had decided to live and die.

1 year, pneumonia 3 months, antibiotics can not cure?

Sci Trans med: Australian scientists have developed new drugs to prevent cardiovascular disease with significantly reduced side effects.