Heart: The association between right ventricular dysfunction and poor prognosis in patients with infectious shock.

Heart muscle dysfunction (SIMD) caused by !---- sepsis can affect the left and right ventriclesHowever, the characteristics and outcomes of simD's various manifestations are not yet clearRecently, a study published in Heart, the leading journal of cardiology, a retrospective cohort study in which researchers used data from the Center for Forward-Looking Registration of Infectious Shock between January 2011 and April 2017Within 72 hours of admission, the researchers will be clinically? An echocardiogram was presumably performed in patients with cardiac dysfunction and recruited into the group (n-778)SIMD is divided into left ventricular (LV) contraction/diastolic dysfunction and right ventricular (RV) dysfunction, as defined by the U.SEchoCardiogram Society standardsThe main outcome of the study was a 28-day mortality rateOf the 778 patients with infectious shock who received an echocardiogram, 270 (34.7%) were SIMsThe median age is 67.0 years, with the male majority (57.3%)Among them, LV shrinkage dysfunction accounted for 67.3%, RV shrinkage dysfunction accounted for 40.7%, LV diastolic dysfunction accounted for 39.3%Although there was no significant difference in serum lactic acid levels and sequential organ failure assessment scores between the two groups, the SIMD group had higher levels of troponin I (0.1 vs0.1 ng/mL;p?0.02) and poor clinical outcomes, including a higher 28-day mortality rate (35.9 vs26.8% ;p.0.01), longer stay in intensive care units (5 vs2 days; p.lt;0.01) and extended mechanical ventilation time (9 vs4 days; p;lt.01)The multivariate analysis showed that isolated RV dysfunction was an independent risk factor for 28-day mortality (OR was 2.26, 95% CI was 1.04 to 4.91)As a result, one-third of patients with infectious shock exhibit various cardiomyopathy disorders Left chamber shrink function is not fully common However, only RV dysfunction is associated with short-term mortality