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Nature Liu Yang et al. Reveal the N501Y mutation of the new coronavirus spike protein enhances virus infection and spread
Time of Update: 2021-12-01
In this study, the human primary respiratory epithelial cell system and a hamster animal model were used to evaluate all amino acid point mutations in the spike protein of the new coronavirus Alpha mutant strain (B.
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Another effect of statins: it can reduce the intestinal flora imbalance of obese people!
Time of Update: 2021-12-01
The results found that Bact2 intestinal type is a potential dysbacterial intestinal type related to systemic inflammation, which is more common in obese people, and taking statins (classic drugs for lowering cholesterol, the treatment and prevention of cardiovascular and cerebrovascular diseases) can reduce the intestine The incidence of tract dysbacteriosis .
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Wang Linqi's team from the Institute of Microbiology, Chinese Academy of Sciences reveals the formation mechanism of the antiviral morphology of fungi induced by the dietary supplement "Guili"
Time of Update: 2021-12-01
● ● ●Recently, the international journal PLoS Genetics published online the research results of Wang Linqi's team at the State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, "A unique cell wall synthetic response evoked by glucosamine determines pathogenicity-associated fungal cellular differentiation" .
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Ruanbang reduces the number of somatic cells in the milk of cows and improves the quality of raw milk
Time of Update: 2021-12-01
in conclusion: 15 days after adding "Ru Anbang", the number of somatic cells in the original milk can be reduced from nearly 500,000/ml to less than 300,000/ml .
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Leading the "Probiotic Food" group standard Ketuo Biological to leverage the hundreds of billions of probiotics market
Time of Update: 2021-12-01
Li Yu said that although the document is a "trial" version, the association has fully taken into account the development trends of the industry and the market, and when formulating the group standard, it is clear that the total number of probiotics in ready-to-eat probiotic foods shall not be less than 10 during the shelf life.
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The Wang Jun team of the Institute of Microbiology establishes new methods for the detection of pathogens targeting RNA, mtNGS and mtTGS
Time of Update: 2021-11-16
Pathogen infection is still a huge problem threatening human health all over the world, and it has brought a heavy burden to clinical diagnosis and treatment . Traditional clinical pathogen identi
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Natural products against pathogenic microorganisms and infectious diseases: an overview of their sources, compounds and chemical diversity
Time of Update: 2021-11-16
Recently, SCIENCE CHINA Life Sciences ("Chinese Science: Life Sciences" in English) published an online review titled "Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities".
Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities.
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[Breakthrough] Scientists discovered missing fragments in the genome of the new coronavirus mutant, which is expected to bring hope to more effective treatment of patients with new coronavirus!
Time of Update: 2021-11-16
This article is original by Translational Medicine Network. Please indicate the source for reprinting. Author: Tiffany Guide: The current foreign epidemic situation continues to spread, and sporadi
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Wang Jun's team from the Institute of Microbiology, Chinese Academy of Sciences establishes new methods for the detection of pathogens targeting RNA, mtNGS and mtTGS
Time of Update: 2021-11-16
Pathogen infection is still a huge problem threatening human health all over the world, and it has brought a heavy burden to clinical diagnosis and treatment . Traditional clinical pathogen identi
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Science supports "cat sucking"?
Time of Update: 2021-11-16
Methicillin-resistant Staphylococcus pseudointermediate (MRSP) is an important emerging zoonotic pathogen that can cause serious skin infections, such as severe atopic dermatitis (commonly known as eczema) .
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[Science] Deciphering the exchangeable genome in bacteria is expected to resist the killing of bacteriophages!
Time of Update: 2021-11-16
This study shows that bacteria have exchangeable genetic elements, which are specifically designed to resist viruses, which enables bacterial populations to switch their inherent innate immune functions at an alarming rate .
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Wang Jun's research group from the Institute of Microbiology, Chinese Academy of Sciences establishes new methods for the detection of pathogens targeting RNA, mtNGS and mtTGS
Time of Update: 2021-11-16
Pathogen infection is still a huge problem threatening human health all over the world, and it has brought a heavy burden to clinical diagnosis and treatment . Traditional clinical pathogen identi
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Nature Microbiology Zhang Yuzhong's team at Ocean University of China reveals a new mechanism of marine bacteria's organic sulfur metabolism and defense
Time of Update: 2021-11-16
Under high concentration of DMSP, DddL degrades DMSP to cause the accumulation of acrylate around the cell, thereby preventing the predation of marine ciliates Uronema marinum, and allowing the ciliates to transfer predation pressure to bacteria in the community that do not contain dddL genes, thereby obtaining Competitive advantages in resources and space .
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Nature Microbiology Zhang Yuzhong's team reveals a new mechanism of marine bacteria's organic sulfur metabolism and defense
Time of Update: 2021-11-16
1038/s41564-021-00981-1 Platemaker: Notes for reprinting on the 11th [Non-original article] The copyright of this article belongs to the author of the article.
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JGG Saccharomyces cerevisiae responds to changes in environmental conditions through transcriptional memory
Time of Update: 2021-11-15
On October 30, 2021, the Journal of Genetics and Genomics published an online research paper entitled "Transcriptional memory of different types of genes is generally maintained under various environmental conditions in Saccharomyces cerevisiae" by Professor Du Haining's team from the School of Life Sciences, Wuhan University .
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PNAS Dr. Li Zhe and others reveal that Epstein-Barr virus small RNA regulates virus growth and transformation
Time of Update: 2021-11-15
Further mass spectrometry analysis revealed that EBER2 mainly regulates the expression of ubiquitin carboxy-terminal hydrolase-1 (UCHL1) to promote the growth and transformation of the virus .
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The Institute of Microbiology, Chinese Academy of Sciences has made important progress in the systematic research of quarantine fungi in my country
Time of Update: 2021-11-15
The root cause of this difficulty is that about half of the species in the quarantine fungi list lack model specimens, strains and reliable reference sequences, and The phylogenetic relationships of most species and their interspecific relationships with near-source species are still unclear, which greatly hinders the research and development of detection methods, not only making front-line quarantine personnel unfounded, but also building smart customs and guarding national biosecurity.
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JGG Huazhong Agricultural University's Peng Nan team and He Mingxiong team developed an efficient editing tool for green bio-manufacturing chassis cells
Time of Update: 2021-11-15
On this basis, the research team used the endogenous CRISPR-Cas system and the MMEJ pathway to develop a rapid genome suitable for Zymomonas mobilis Tools for editing and identification of essential genes .
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Microbiology Institute Mi Kaixia team reveals the molecular mechanism of mycobacterial epigenetic regulation of isoniazid resistance
Time of Update: 2021-11-14
Based on the research results, we propose a new molecular mechanism for mycobacterial epigenetic regulation of isoniazid resistance--HsdM modifies the transcription level of genes through methylation modification, which changes the redox state of mycobacteria, thereby reducing tuberculosis bacteria Sensitivity to isoniazid (Figure 2) .
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Nature Microbiology Zhou Zhenghong's group reveals the molecular mechanism of BTV virus invasion
Time of Update: 2021-11-14
The article on low endosomal pH during viral entry uses the double-stranded RNA virus bluetongue virus (BTV) as the research object to analyze the conformational changes and the mechanism of invasion of non-encapsulated diseases induced by late endosome low pH .
