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The brain organs develop the optic cup
Time of Update: 2021-08-26
" The corresponding author of the paper, from University Hospital Dusseldorf, Germany Jay Gopalakrishnan said, "These organoids can help study brain-eye interactions during embryonic development, model congenital retinal diseases, and generate specific retinal cells to test personalized medicines and transplant treatments .
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"Metabolism" uncovers the "truth" of Zika virus infection
Time of Update: 2021-08-26
"These studies not only provide powerful big data resources for clinical understanding of the molecular mechanism of microcephaly caused by Zika virus infection, but also propose the potential value of intervention in NAD+ metabolism in its clinical treatment and drug development .
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Nutrition interferes with metabolism, and the flora becomes the "commander"
Time of Update: 2021-08-26
Researchers Lin Xu and Chen Yan from the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences collaborated for the first time through a clinical nutrition intervention study and found that peanuts instead of refined grains can increase the reversal rate of metabolic syndrome, and found that intestinal flora is guiding precision nutrition intervention to improve metabolism.
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The regulatory mechanism of tRNA m7G modification in tumors revealed
Time of Update: 2021-08-26
The regulatory mechanism of tRNA m7G modification in tumors revealed The regulatory mechanism of tRNA m7G modification in tumors is revealed The regulatory mechanism of tRNA m7G mod
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Science blockbuster: new mRNA delivery SEND, opening up a new method of molecular therapy delivery
Time of Update: 2021-08-26
The new RNA delivery platform SEND (Source: MIT) The research was published in the latest issue of Science with the title "Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery" .
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Phase I clinical study shows that the neutralizing antibody "MW33" injection can effectively block the new coronavirus
Time of Update: 2021-08-26
Recently, Fudan University professor Lu Hongzhou’s clinical trial of an effective drug neutralizing antibody "MW33 injection" for the prevention and treatment of new coronavirus infections showed that its safety, tolerability, and pharmacokinetic characteristics have a stable antibody structure.
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New research is expected to change the clinical practice of nasopharyngeal carcinoma
Time of Update: 2021-08-26
It evaluated the efficacy and safety of teriprizumab or placebo combined with GP chemotherapy in the first-line treatment of recurrent/metastatic nasopharyngeal carcinoma.
7 months higher than that of the placebo group, and the patients’ progression-free survival time was significantly prolonged; The 1-year PFS rate in the replimumab combined chemotherapy group was 49.
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"The jewel in the crown" of heart surgery in Fudan Zhongshan Hospital
Time of Update: 2021-08-26
Recently, the Journal of Thoracic and Cardiovascular Surgery (JTCVS) published the research results of Wang Chunsheng, professor of cardiology surgery at Zhongshan Hospital of Fudan University, on the application of David's surgery to the treatment of acute aortic dissection .
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Malaria prevention measures are expected to "upgrade"
Time of Update: 2021-08-26
It shows the importance of targeting the immune response to key regions of the protein produced during the sporozoite stage of Plasmodium falciparum .
The research team isolated the CSP antibody from a person who received an experimental malaria vaccine for the first time .
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Latest research: Drinking green tea may prevent and delay Alzheimer's disease
Time of Update: 2021-08-26
At the same time, green tea extract significantly increased the expression of synaptic proteins PSD95 and Synaptophysin reflecting the damage of nerve synapses, weakened the neurotoxicity caused by β-amyloid protein, and delayed the progression of the disease in mice with Alzheimer's disease .
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Newborn hypoxia cooling therapy is questioned
Time of Update: 2021-08-26
However, the results of a study of births in low- and middle-income countries showed that in many cases, this treatment cannot prevent brain damage, but is associated with increased mortality .
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Yu Jintai's team found a new target for drug treatment for Alzheimer's disease
Time of Update: 2021-08-26
The results found that the transcription and protein expression levels of ACE in the serum tissues of AD patients were significantly lower than those of ordinary controls, and Mendelian randomization analysis supports the causality between it and the occurrence of AD .
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New technology can identify living brain proteins
Time of Update: 2021-08-26
Image source: Northwestern University For the first time, researchers have developed a new method that can identify proteins in the brains of living animals, a big step toward understanding the millions of different proteins in different types of neurons .
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A wine ingredient can be used for controllable tumor immunotherapy
Time of Update: 2021-08-26
Just recently, Chinese scientists creatively developed a gene expression device regulated by resveratrol, and took the lead in applying it to controllable tumor immunotherapy to achieve precise control of T cell activity .
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The initiation mechanism of neurohomeostasis plasticity is like this
Time of Update: 2021-08-26
On August 17, the team of Zhou Zikai, a researcher at the Shanghai Institute of Materia Medica , Chinese Academy of Sciences, and Zhengping Jia, a professor at the University of Toronto/Toronto Children’s Hospital in Canada , reported on Cell Reports on the neurotrophic factor NGPF2 and its related molecular mechanisms that drive neurohomeostasis plasticity.
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Precision treatment platform can achieve combined chemical and photothermal therapy for breast cancer
Time of Update: 2021-08-26
Both in vitro and in vivo experiments show that the in situ nanoenzyme amplified near-infrared two-zone tumor precision treatment platform can accurately and effectively ablate tumors, realize the combined treatment of breast cancer with CDT-PTT, and at the same time cause non-specific damage to normal tissues.
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Middle-aged fattening, pregnancy gaining weight...not the "excessive" of low metabolism
Time of Update: 2021-08-26
Most stable consumption in middle ageMost stable consumption in middle age From babies falling to the ground to elderly people in their twilight years, in this expedition that spans life, researchers have found the "peaks" and "lows" of human metabolism in more than 6000 subjects in 29 countries around the world.
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High-fat diet damages intestinal flora and promotes heart disease
Time of Update: 2021-08-26
Byndloss said the study revealed a previously unexplored mechanism of how diet and obesity can increase the risk of cardiovascular disease by affecting the relationship between the gut and intestinal microbes .
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This antibody can treat new coronavirus mutant infections
Time of Update: 2021-08-26
This antibody can treat new coronavirus mutant infections This antibody can treat new coronavirus mutant strain infection This antibody can treat new coronavirus mutant strain infec
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Innovative drugs bring good news to obese patients
Time of Update: 2021-08-26
Innovative drugs bring good news to obese patients Innovative drugs bring a gospel to obese patients Innovative drugs bring a gospel to obese patients Recently, the Lancet Magazine EClinicalMedicine published a report by Chinese scholars about the glucagon-like peptide-1 receptor (GLP-1R)/glucagon receptor (GCGR) dual agonist IBI362 in China for overweight or obese patients.
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