 Home > Medical News > Medical Science News > Middle-aged fattening, pregnancy gaining weight...not the "excessive" of low metabolism

Middle-aged fattening, pregnancy gaining weight...not the "excessive" of low metabolism

 Last Update: 2021-08-26
 Source: Internet
 Author: User

Tags

what epigenetic changes

antibodies antigens related

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Middle-aged fattening, pregnancy gaining weight.

"Middle-aged people are not as good as before" "Metabolism drops, and drinking water makes you fat", is this really the case? A new result proves that this is not the case
.

Chair Professor of the School of Pharmacy, Shenzhen University of Technology, Chinese Academy of Sciences, Chief Scientist of the Energy Metabolism and Reproductive Research Center, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, John Roger Speckman team, and Associate Professor of Evolutionary Anthropology, Duke University Herman Ponze’s team and many other international teams have found that infants have the highest metabolism, and that people’s metabolism really begins to decline after the age of 60, and the culprit of "middle-aged blessings" is not low metabolism
.

Relevant research results were published in "Science" on August 13

Most stable consumption in middle age

From babies falling to the ground to elderly people in their twilight years, in this expedition that spans life, researchers have found the "peaks" and "lows" of human metabolism in more than 6000 subjects in 29 countries around the world.
It is the first time to reveal the metabolic law of the whole life cycle
.

Many people believe that the metabolic rate will reach its peak in the teens to twenties
.

In fact, babies have the highest metabolic rate

"Part of the reason may be that infants who are a few weeks old are not active until they are about 1 year old
.

At the same time, the resting metabolic rate of infants has also risen sharply, which may be related to their rapid growth

After a rapid increase in the early stages of infancy, the metabolic rate will slow down at a rate of about 3% per year until about 20 years old, and then stabilize
.

Although the growth of adolescents has soared, the data show that the daily energy needs of adolescents do not seem to have any increase
.

"We originally thought that the metabolic rate in adolescence would be different, but that is not the case,

Surprisingly, studies have found that the metabolic rate and energy expenditure of young and middle-aged people in their 20s to 50s are the most stable
.

Even during pregnancy, as the baby grows, the energy requirements of pregnant women only increase with weight gain, and their own energy requirements have not risen significantly

"After the age of 30, the body's various functions decline, waist circumference becomes thicker, and changes in metabolism are not the cause
.

" Spikeman said

It really started to decline at the age of 60
.

Studies have pointed out that the human body's metabolic rate does not really start to decline until after the age of 60, and it slowly declines at a rate of 0.
7% per year

A thought on the law of life

Looking at the metabolic law of the life cycle, what exactly affects the human body's metabolic level?

Pang Ze said that with age, the loss of muscle mass may be part of the reason for the decline in metabolism, because muscle burns more calories than fat, but this is not the whole reason
.

Spikeman said that although the biggest factor affecting metabolism may be the amount of muscle tissue in the body, the amount of muscle tissue itself is also affected by weight, gender, and age
.

The mechanism of energy demand changes over time is currently not fully understood
.

Exploring the laws of life is a long process
.
Spikeman said that the results of this research overturned people's understanding of metabolism, and also indicated that we may need to re-examine the energy requirements and nutritional strategies of the developmental and aging stages
.

"The study can estimate energy requirements, and people can more accurately calculate how much food they need to eat to ensure nutrition and avoid weight gain
.
We are currently establishing contact with a Chinese company that provides dietary advice online
.
" Beckman said that from a broader perspective, only by understanding the energy needs of the population can you know how much food needs to be produced and where the red line of food security is
.

Evaluation of opinion articles published at the same time by "Science": This research provides important new insights for the study of human metabolism
.
The outstanding collaborative spirit of the team made this research of unprecedented scale and scope possible
.

A global cooperation that follows the "gold standard"

This is a large-scale international cooperation with nearly 100 international teams participating.
The research samples cover almost all age groups from babies just one week after birth to 95-year-olds
.

In the past, scientists have carried out many large-scale studies in the field of metabolism, but they only focused on measuring the basic metabolic rate of the human body, that is, the energy consumed by the human body for important basic functions such as breathing, digestion, and pumping
.
However, this part of the basic energy required to maintain life only accounts for 50% to 70% of the body's total daily energy consumption
.
Humans do housework, exercise, and even thinking and fidgeting in daily life will consume energy.
However, in previous studies, the energy required for these daily activities has not been included in large-scale studies
.

In this regard, the researchers used the "double standard water" method to measure the total energy consumed by people every day
.

"Double standard water" is a measurement technique used by scientists to measure human energy consumption since the 1980s
.
Collect urine and analyze the changes in the abundance value of markers in the urine to understand the body's energy metabolism
.

Because of its accuracy and precision, this technology is considered to be the "gold standard" for measuring daily energy consumption under free movement outside the laboratory
.

However, due to the high cost of such research and the limited scale and scope of the research, multiple laboratories decided to share relevant data and integrate the measurement results in a database
.

"For a huge database, integrating and managing data is the most difficult part.
We designed a new equation to convert the data analyzed in different ways in different laboratories into a common method, which answered that a single research team could not answer.
question
.
"International Atomic energy Agency as" doubly labeled water "main person responsible for the database project, Sibikeman said it is based on the" doubly labeled water method for accurate detection "technology, the research team examined people's daily total energy consumption Numerical values, through the collection and analysis of energy consumption data throughout the life cycle, and observation of the human body’s metabolism rules, these phenomena have been discovered
.
(Source: China Science News, Diao Wenhui and Han Yangmei)

Related paper information: https://doi.
org/10.
1126/science.
abe5017

https://doi.
org/10.
1126/science.
abe5017

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.