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Latest research: Drinking green tea may prevent and delay Alzheimer's disease |
Professor Wan Xiaochun of the State Key Laboratory of Tea Tree Biology and Resource Utilization of Anhui Agricultural University and the research group of Professor Shen Yong of the University of Science and Technology of China found that green tea can prevent and delay amyloid β, which is one of the characteristic pathological indicators in the brain of Alzheimer’s model mice Protein formation reduces nerve synapse damage and improves learning and memory ability
.
The results were published online in "Molecular Nutrition and Food Research" a few days ago
The study used green tea extract to intervene in Alzheimer’s model mice (that is, transgenic mice that can produce human-derived amyloid beta mutant genes).
It was found that the green tea extract It significantly reduces the content of amyloid β in the mouse brain, reduces the content of the inflammatory factor IL-1β in the brain and the expression of glial cell activation markers Iba1 and GFAP, and inhibits its excessive activation
.
At the same time, green tea extract significantly increased the expression of synaptic proteins PSD95 and Synaptophysin reflecting the damage of nerve synapses, weakened the neurotoxicity caused by β-amyloid protein, and delayed the progression of the disease in mice with Alzheimer's disease
.
Behavioral tests further proved that the intervention of green tea extract significantly improved the cognitive ability of Alzheimer's model mice
With the aging of the population, neurodegenerative diseases represented by Alzheimer's disease are showing a rapid and high incidence trend, but there is no complete cure yet, and prevention is an important means
.
Tea is a healthy beverage with multiple functions.
The research shows that green tea may prevent and delay Alzheimer's disease, and provide a theoretical basis for elucidating the mechanism of drinking tea to prevent Alzheimer's disease and further transformation and application
.
(Source: Gui Yunan, China Science News)
Related paper information: https://doi.
https://doi.
org/10.
1002/mnfr.
202100626 https://doi.
org/10.
1002/mnfr.
202100626