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Merck voluntarily withdraws Keytruda's indications for the treatment of patients with metastatic small cell lung cancer
Time of Update: 2021-03-18
5;">On March 1, Merck announced that the company would voluntarily withdraw Keytruda (pembrolizumab) in the United States for the treatment of patients with metastatic small cell lung cancer (SCLC), these patients in platinum chemotherapy and at least one other previous chemotherapy or The disease progressed afterwards.
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Research finds vitamin K2 particles can improve bone health
Time of Update: 2021-03-18
Chinese Academy of Sciences Osteoporosis is a common debilitating bone disease, which is characterized by bone loss and bone structure degradation, mainly caused by the disruption of the balance between bone formation by osteoblasts and bone resorption by osteoclasts.
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Pfizer's long-acting growth hormone somatrogon and 20-valent pneumonia vaccine enter review in the EU
Time of Update: 2021-03-18
(Sina Pharmaceutical News)Last Friday, Pfizer announced that the company has two product marketing authorization applications accepted by the European Medicines Agency, one is the long-acting human growth hormone somatrogon, and the other is the 20-valent pneumococcal conjugate vaccine 20vPnC.
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2 fruits + 3 vegetables = the secret of longevity
Time of Update: 2021-03-17
com) This week, a study by the American Heart Association revealed the "secret of longevity": eating 2 kinds of fruits and 3 kinds of vegetables every day.
This week, a study by the American Heart Association revealed the "secret of longevity": eating 2 kinds of fruits and 3 kinds of vegetables every day.
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Weight loss "game changer" is born
Time of Update: 2021-03-17
A large global study conducted by researchers from University College London, UK showed that one-third (35%) of people lost more than one-fifth (20% or more) of their weight after taking a new drug for the treatment of obesity.
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Chinese scientists discover a new mechanism for RNA modification to regulate chromatin
Time of Update: 2021-03-17
6 The researchers said that the study found that a chemically modified RNA can "monitor" and shut down DNA with "foreign sequences", thereby proposing a new pathway for RNA to regulate genetic information and proving the important function of this pathway in stem cell maintenance.
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New breakthrough in the field of anti-fibrosis, Ted's overseas authorization sets a record
Time of Update: 2021-03-17
5;">Obtained the national major new drug creation support FDA approval for clinical trials in the United States5;">To this end, in January 2017, Tide Pharmaceuticals formally established the first original innovative drug project-a class 1 small molecule drug TDI01 for the treatment of idiopathic pulmonary fibrosis, which was awarded by the Chinese Academy of Medical Sciences and Peking Union Medical College.
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Dirty air affects children's heart health
Time of Update: 2021-03-17
Parker Allergy and Asthma Research Center at Stanford University, said, “Even a brief exposure to air pollution can actually change the regulation and expression of children’s genes, and may also change blood pressure.
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Disgust protects oneself from disease
Time of Update: 2021-03-17
In the first study on disgust and the health of indigenous peoples, Sugiyama and colleagues found that those Shuars who are most averse to raw or spoiled foods and other potential sources of pathogens have difficulty fighting viral or bacterial infections.
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"Heart scar" is bad, there is a way!
Time of Update: 2021-03-17
Chinese Academy of Sciences Chinese Academy of Sciences Chinese Academy of Sciences Another wayAnother way Chang Jiang told the Chinese Journal of Science that this solution is to use a degradable hydrogel that releases active strontium ions to improve the survival of myocardial cells after myocardial ischemia/reperfusion, promote angiogenesis, and restore the damaged heart function and heart function.
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First discovery: the active microbiome has been colonized in the intestine of sheep fetus
Time of Update: 2021-03-17
Photo courtesy of Feed Institute of Chinese Academy of Agricultural Sciences Recently, the ruminant feed innovation team of the Feed Research Institute of the Chinese Academy of Agricultural Sciences revealed for the first time that there are active gut microbes before the birth of sheep fetuses, and determined the composition of the microbes and their active metabolites.
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Astrocytes derived from patients with bipolar disorder affect neuronal activity
Time of Update: 2021-03-17
In the new study, they compared the inflammatory characteristics of induced pluripotent stem cell-derived astrocytes produced by 6 patients with bipolar disorder and 4 healthy individuals.
In patients with bipolar disorder, IL-6 mediates at least to some extent the effects of inflammatory astrocytes on nerves.
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Complications of hematopoietic stem cell transplantation are expected to usher in new drugs
Time of Update: 2021-03-17
Recently, the US FDA accepted Ruxolitinib (Jakafi)'s Supplemental New Drug Application (sNDS) and granted it priority review as a potential treatment for patients with steroid refractory chronic graft-versus-host disease 12 years of age and older select.
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Scientists reveal the molecular mechanisms that affect the pathogenicity and spread of influenza viruses
Time of Update: 2021-03-17
Photo courtesy of Harbin Animal Research of Chinese Academy of Agricultural Sciences The replication ability and pathogenicity of the SUMO-modified mutant virus in mice are significantly reduced.
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Mercadon stopped developing coVID-19 vaccine candidates
Time of Update: 2021-03-09
January 25, Mercadon announced that it would stop developing COVID-19 candidate vaccines V590 and V591, and plans to focus its COVID-19 research strategy and production capacity on advancing MK-4482 and MK-7110 therapeutic candidates.
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The treatment of BPDCN by ELZONRIS in Manarini has been approved by the European Commission
Time of Update: 2021-03-09
“ For BPDCN patients in Europe, this is the first time they have the potential to benefit from this treatment for this malignant tumor," said Elcin Barker Ergun, CEO of Menarini Group.
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Hundred-time Meishi Shiguibao Zeposia in the European Union formally applied for a new adaptive disorder
Time of Update: 2021-03-08
The data showed that the study reached two main endpoints: induced clinical remission in the 10th week of induction and maintaining clinical remission in week 52 of the maintenance period all showed results with high statistically significant (p At present, Shishi Meishiguibao is also conducting Phase III YELLOWSTONE clinical trial project to evaluate Zeposia's treatment of patients with moderate to severe active Crohn's disease (CD).
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Step Pharmaceuticals four-price influenza virus lysing vaccine approved for clinical trials
Time of Update: 2021-03-08
January 4, Step Pharmaceuticals announced that its controlling subsidiary, Zhejiang Tianyuan Biopharmaceutical Co., Ltd., had recently received a "Drug Clinical Trial Approval Notice" for the four-price influenza virus lysed vaccine approved by the State Drug Administration.
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Pfizer filed a 4/6 inhibitor new adaptor listing application in China
Time of Update: 2021-03-08
In addition, in April 2019, Pybersili was approved by the FDA to be used in association with aromatase inhibitors or fluorovis groups to treat patients with breast cancer in men with HR-plus/HER2-advanced or metastasis.
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The clinical results of BCMA targeted therapy were positive
Time of Update: 2021-03-08
The latest clinical results published by ASH show that among patients treated with the recommended dose of teclistamab in phase 2 clinical trials of subsulte injection form, ORR reached 73% (16/22), of which 55% achieved very good partial remission (VGPR) and 23% achieved complete remission (CR).
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