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| Chinese scientists discover a new mechanism for RNA modification to regulate chromatin |
On March 4, "Nature" published the latest research results of Chen Jiekai's group, a researcher at the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences.
Beijing Genomics Institute, Chinese Academy of Sciences, the National Center for Biotechnology Information researcher Yangyun Gui noted that the results reveal a new function regulation of chromatin, the understanding of RNA methylation (adenosine No.
Yang Yungui pointed out that this result reveals the new function of regulating chromatin, and has new inspiration for understanding the physiological function of upper adenosine 6 methylation ( m 6 A), chromatin regulation, and stem cell stemness regulation.
Chromatin is the carrier of genetic information, which can be divided into euchromatin with active transcription and heterochromatin with inactive transcription to realize the switch of genetic information, but the mechanism of how this "switch" specifically regulates is still unclear.
The researchers found that heterochromatin is formed by having a m .
6 6
The researchers explained that biological macromolecules such as DNA, RNA, and proteins can be modified by sophisticated biochemical reactions.
6
In addition, scientists also found that this mechanism regulates the stemness of embryonic stem cells.
Related paper information: org/10.
org/10.
1038/s41586-021-03313-9" target="_blank">https://doi.
org/10.
1038/s41586-021-03313-9
