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Nature Sub-Journal: In order to deal with antibiotics, bacteria actually staged a "metamorphosis"!
Time of Update: 2021-03-25
Specifically, through single-cell experiments, researchers found that the cells of Caulobacter crescentus, a commonly used model organism, can restore the growth rate before being stimulated by antibiotics and undergo significant changes in morphology.
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Nature Protocols: The Baiyang Group of the Institute of Genetics and Development publishes a method for high-throughput isolation, culture and identification of root bacteria
Time of Update: 2021-03-25
Original link: https:// Nature Protocols: Baiyang Group of Institute of Genetics and Development of Chinese Academy of Sciences published an article detailing the experimental procedures and analysis of high-throughput isolation, culture and identification of plant root bacteria Methods The research of plant root microbiome mainly relies on high-throughput amplicon and metagenomic sequencing technology to describe the species classification and genetic composition of the microbiome.
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Science Advances | Great Discovery!
Time of Update: 2021-03-25
This study shows that methanogenesis already exists in the common ancestor of Euryarchaeota, TACK archaea and Asgard archaea, and it is likely to occur in the late Hadean or early Archean, and the ancestral methanogens depend on methylated compounds and hydrogen.
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[ISME] Break the existing conclusions!
Time of Update: 2021-03-25
Recently, the research groups of Dong Xiuzhu and Zhou Yuguang of the Institute of Microbiology of the Chinese Academy of Sciences conducted research on strains of Flavobacterium glacialis collected from Tibet, Xinjiang, Gansu, Sichuan and other places, and found that a carotenoid called zeaxanthin helps them in hypoxia.
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【Inventory】The latest research progress in the field of intestinal microbiology
Time of Update: 2021-03-25
1038/s41588-020-00763-1 January 18, 2021, from Researchers from the University of Groningen Medical Center in the Netherlands published a study titled Large-scale association analyses identify host factors influencing human gut microbiome composition in "Nature Genetics".
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Researchers discover new species-specific hepatitis C virus host factor
Time of Update: 2021-03-25
Researcher Zhong Jin's group at the Shanghai Pasteur Institute of the Chinese Academy of Sciences collaborated with Peking University professor Wei Wensheng's group to publish a research paper titled TRIM26 is a critical host factor for HCV replication and contributes to host tropism on Science Advances.
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Wang Ertao's research group and collaborators reveal the co-evolutionary mechanism of arbuscular mycorrhizal symbiosis and nodule symbiosis
Time of Update: 2021-03-25
Research progress On December 9, 2020, Molecular Plant published online a research paper entitled "Mycorrhizal Symbiosis Modulates the Rhizosphere Microbiota to Promote Rhizobia Legume Symbiosis" completed by Wang Ertao's research group and cooperating team of the Center for Excellence in Molecular Plant Science of the Chinese Academy of Sciences.
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In vitro test: mutant new coronavirus discovered in South Africa may reduce the effect of Pfizer vaccine
Time of Update: 2021-03-25
In response to the results of the study, a researcher from the University of Texas Medical Department said in an interview that although the mutant virus may reduce the effectiveness of the Pfizer-BioNTech vaccine, the vaccine still has a protective effect against the new coronavirus.
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Researchers have developed the second-generation microbiome search engine MSE 2
Time of Update: 2021-03-25
Recently, the Single Cell Research Center of Qingdao Institute of Bioenergy and Processes, Chinese Academy of Sciences released the second-generation microbiome search engine MSE 2 (http://mse.
The overall framework of the second-generation microbiome big data search engine MSE 2 Source: Qingdao Institute of Bioenergy and Processes, Chinese Academy of Sciences
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AMEM Review | The Influence of Host Genetics on the Intestinal Microflora
Time of Update: 2021-03-25
Although research results have shown that environmental factors such as diet and lifestyle affect the composition of the intestinal flora, the role of host genetics is still unclear.
These research characteristics are very important for host genetic significance, especially in twin studies of intestinal flora.
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Looking at the biology of the new coronavirus from the perspective of Crisp(r) gene editing technology | Cell Press
Time of Update: 2021-03-25
You can find the submission policy of COVID-19-related papers, as well as the papers on the epidemic and virus published in the journals of Cell Press on the resource center page.
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When is the most effective medicine?
Time of Update: 2021-03-25
Recently, in a study published in "Science Advances", an international research team led by the University of Munich in Germany found for the first time that there are also biological clocks in non-photosynthetic bacteria.
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Nature | Guo Hun and others reveal the molecular mechanism of bedaquiline inhibiting Mycobacterium tuberculosis
Time of Update: 2021-03-25
Recently, the John Rubinstein team of Hospital for Sick Children in Canada published an article Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline in Nature.
A Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis.
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Genes that promote the unique biology and intrinsic antibiotic resistance of enterococci
Time of Update: 2021-03-25
In order to identify genes that confer this unique attribute, Michael's team used Tn-seq technology to fully explore the genome of Enterococcus faecalis strain MMH594, looking for genes that are important for growth in nutrient-containing media and have low-level antibiotic attack.
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Chinese scientific research team found that the diversity of new coronaviruses in intestinal samples is higher than that of respiratory tract
Time of Update: 2021-03-24
The State Key Laboratory of Respiratory Diseases of Guangzhou Medical University announced on February 23 that the team of Professor Zhao Jincun of the laboratory has cooperated with Shenzhen Huada Life Sciences Research Institute and other units to find that patients with new coronary pneumonia at different time points and different physiological parts (respiratory tract, The gastrointestinal) virus quasispecies mutation and evolution characteristics provide important theoretical guidance for the evolution of the new coronavirus and the emergence of mutant strains.
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[Plant Cell] How do bacteria obtain iron from plants?
Time of Update: 2021-03-23
On March 5, 2021, Liu Jun's research group from the Institute of Microbiology of the Chinese Academy of Sciences published a research paper entitled "Bacterial effector targeting of a plant iron sensor facilitates iron acquisition and pathogen colonization" in the international authoritative academic journal The Plant Cell.
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The Wang Jun research group of the Institute of Microbiology has made continuous progress in the research of regulating the composition and function of the microbiome and the positioning of host genes
Time of Update: 2021-03-23
The human genome interacts closely with the genes and microbiome related to metabolism and immunity, which may affect the diversity of microorganisms; however, as the microbiome is a complex ecosystem, there are a large number of random factors interfered, so the human body influences the host microbial composition Genome-wide association studies (GWAS) must be carried out in a large population of genes, and a series of innovations in analysis methods must be carried out at the same time.
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[Science] First discovery!
Time of Update: 2021-03-23
In summary, the study shows that fake flowers are a novel flower mimicking system that attracts insect pollinators to bring their conidia into the carrier through visual and olfactory cues, which may help this fungus hybridize and infect previously uninfected plant.
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Sub-Journal of "Nature": The more unique the intestinal bacteria, the longer the life span!
Time of Update: 2021-03-23
Researchers analyzed data from more than 9,000 people in three cohorts and found that from adulthood to old age, the composition of the human intestinal bacteria will become more and more unique, and the more healthy the individual, the more unique it will be.
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Advances in research on host gene mapping that regulates the composition and function of the microbiome
Time of Update: 2021-03-23
Recently, Nature Genetics published online the latest research results of the international large-scale research project "MiBioGen"——Large-scale association analyses identify host factors influencing human gut microbiome composition.
