Azide reagents and the reactions involved (3)

2.

(1) NaN ₃ is a highly toxic substance.

According to the national standard GBZ/T160.

(2) All utensils and post-treatment aqueous solutions that have been in contact with NaN3 need to be swashed with sodium hypochlorite solution in a negative pressure fume hood to completely quench

(3) After the reaction, the pH of the reaction solution must be greater than 9 to be extracted (it will not become a highly toxic and explosive substance HN3 that cannot be washed away by water)

(4) The product with azide group is explosive (unless the above 3 safety indicators are met, and the amount is small, such as only 1g or less)

It is best to combine the reaction in the next step to see what solvent it is.

(5) Treat the excess NaN in the reaction; post-processing the aqueous solution, make a dilute aqueous solution at a concentration of more than 1:50, slowly add it to the NaClO solution under constant stirring for quenching, stir thoroughly and let it stand overnight

2NaN ₃ +NaClO+H ₂ O=2NaOH+NaCl+3N ₂ ↑

It can also be treated with dilute cerium ammonium nitrate or nitrous acid (mostly with its sodium salt aqueous solution)

Organic azide compounds are prepared by the nucleophilic reaction meter of pseudo-halogen secondary reaction kinetics.

Azide compounds with explosive properties cannot be stored in pure or even concentrated solutions, but in the form of dilute solutions