Chinese doctors starve cancer cells to glucose deprivation and destroy lactate and hydrogen ions

After years of research, the theory that Chinese doctors starve cancer cells has been applied to actual cases "Cancer cells also need to eat to survive If they are deprived of food, they will die." Hu Xun, a professor at the Institute of oncology, Zhejiang University, said that following this seemingly simple principle, he and his research team found a new treatment for "starving" cancer cells, which was published in eLife, an international authoritative journal in the field of biology and medicine, and was recognized by internationally renowned oncologists After many years of basic research, Hu Xun found that glucose is something that cancer cells must "eat" In fact, if they are deprived of glucose, cancer cells will die But in fact, when the glucose supply is insufficient, the tumor does not starve to death and keeps growing Professor Hu Xun explained the secret: there is a large amount of lactic acid in the tumor, which is dissociated into lactic acid anion and hydrogen ion, and becomes two "helpers" of cancer cells, so that they can determine the "consumption" according to the "food" The two "helpers" work together to make cancer cells use glucose sparingly when the glucose content is low; when there is no glucose, they enter the "dormancy" state; when there is glucose supply, they immediately return to the growth state Therefore, if we want to effectively starve cancer cells, we should not only deprive glucose, but also destroy the synergistic effect of lactate anion and hydrogen ion In the case of glucose starvation or lack, as long as either of these two factors is removed, cancer cells will die quickly Researchers use sodium bicarbonate (baking soda) to remove hydrogen ions from tumors, which can destroy the synergistic effect of lactate and hydrogen ions, so as to quickly and effectively kill tumor cells in glucose starvation or lack It is the key to transform the basic scientific research results into the clinical treatment of tumor, so that more patients can benefit Research team leaders Chao Ming and Hu Xun In 2012, Chao Ming, a radiologist with 30 years of clinical experience, and Hu Xun, a team of radiologists from the Second Affiliated Hospital of Zhejiang University School of medicine, joined hands in the research on a new type of treatment for primary liver cancer, and named this method as "artery catheterization chemoembolization targeting lactate anion and hydrogen ion in tumor", or "tila-tace" In clinical practice, Chao Ming explained: "conventional transcatheter arterial chemoembolization (ctace) cuts off the tumor's food channel, and then we use sodium bicarbonate to remove the hydrogen ion in the tumor, which is equivalent to not only not eating the tumor, but also letting it go to the gym to consume quickly and starve to death." The results of clinical research are gratifying The results of their clinical research show that: 37 cases were treated with ctace, 18 cases were effective; 40 cases were treated with tila-tace, 40 cases were effective In addition, in this clinical study, the liver cancer treated with tila-tace is difficult to treat The international comprehensive report shows that the average effective rate of ctace is 35% 35% to 100%, such a huge contrast not only makes the international peers very cautious when accepting this article, but also the two professors have been carrying out the research with suspicion "At present, according to preliminary statistics, the median survival period of patients has exceeded three and a half years; follow-up large-scale randomized controlled study is needed If it is confirmed to be effective, it is a leap for the treatment of liver cancer." Two experts said.