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(7) Omics technology
In order to efficiently track the abuse of ASs, it is necessary to develop new screening techniques for illicit drug screening
.
Based on "omic" technologies such as transcriptomics, proteomics, and metabolomics, the abuse of anabolic hormones can be discovered through indirect detection of their physiological effects
Riedmaier et al.
introduced the application of these omics techniques to search for ASs biomarkers and the potential to detect their residues
.
The research team monitored the use of ASs by identifying potential gene expression biomarkers in bovine blood cells
In 2011, Anizan et al.
used steroid targeted phase II metabolite analysis to investigate and analyze the abuse of natural steroid hormones during animal reproduction
.
The study adopted exogenous administration of androstenedione to animals, looking for potential biomarkers, and monitoring the residual status of steroid steroid hormones in animals
Based on the physiological changes caused by ASs, the use of omics technology to develop a new screening method and to detect its residual content, this technology will be very promising
.
Some very sensitive methods, such as quantitative RT-PCR and mass spectrometry, can quantify subtle changes in gene, protein expression or metabolites.
