Determination of Benzimidazoles——Liquid Chromatography-Mass Spectrometry

(4) Liquid chromatography-mass spectrometry (LC-MS)

LC-MS is a trace monitoring and analysis technology that has developed rapidly in recent years.

1) Liquid chromatography-single quadrupole mass spectrometry (LC-MS)

In the early detection of BMZs residues in animal tissues, liquid chromatography-single quadrupole mass spectrometer (LC-MS) was often used, which usually used thermal spray ionization (TSP) interface and selected ion (SIM) mode

2) Liquid chromatography-quadrupole tandem mass spectrometry (LC-MS/MS)

In the past ten years, the application of tandem mass spectrometry (MS/MS) has greatly improved the ability to detect and confirm BMZs residues in biological samples.

Chen Ying et using UPLC-MS / MS for simultaneous determination of animal tissues thiabendazole , oxfendazole , mebendazole , trichlorobenzene metronidazole residues in five kinds BMZs fluorobenzene metronidazole and the like

De Ruyck et al.

De Ruyck and others also established an LC-ESI-MS/MS multi-residue detection method for the detection of 8 anthelmintics (including TBZ, OFZ, FBZ, OXI, ABZ, FEB and TCB) in milk

Wojnicz et al.

Whelan et al.

3) Liquid chromatography-ion trap mass spectrometry (LC-MSn)

Since the mid-1980s, ion traps have become mass analyzers for organic mass spectrometry

Related Links: Determination of Benzimidazole Drugs-High Performance Liquid Chromatography