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Polylactic acid (PLA), also known as polylactide, is a type of aliphatic polyester polymerized from lactic acid as a monomer
.
Compared with PLA, PGA has one less main chain unit, so it has better hydrophilicity and faster hydrolysis rate than PLA.
The copolymerization of PGA and PLA into poly(lactide-co-glycolide) (PLGA) can significantly improve PLA.
degradation rate
.
At present, the preparation of PLGA mostly adopts the ring-opening polymerization method
.
The proportion of PGA and PLA in the PLGA copolymer is different, and its crystallinity is also different.
The crystallinity of the copolymer is different, and its water absorption rate is different
.
In addition to its application as a conventional degradable plastic, PLGA is widely used as a functional pharmaceutical excipient to control the release of parenteral drugs, and for the production of bioabsorbable implantable medical devices for applications such as orthopedics, cardiovascular and wound healing
.
Recently, Donggeng New Materials has launched a new PLGA functional polymer technology, which integrates the advantages of molecular structure regulation, reduction of processing temperature, regulation of crystallization speed and improvement of polymer thermal stability, which can significantly improve the comprehensive performance of PLA and PGA
.
Donggeng has complete technical solutions for degradable materials (PLA, PGA, PBS, PLGA, PPC, PCL).
From chemical research and development to process package development, from key equipment manufacturing to pilot service, the combination of different dimensions creates process solutions.
optimal solution of the program
.
At present, the commercialized projects include PLA and PBS, and those still in the pilot stage include PGA/PLGA/PXA.
In addition, Donggeng has also increased investment in the research and development of PPC and PCL processes and equipment to meet future industry development needs
.
After years of continuous research and development and process optimization in the synthesis, purification and polymerization process of lactide, Donggeng has reached the leading level in the industry
.
The two PLA manufacturers serviced by Donggeng have been successfully put into production, providing stable and high-quality products for the market, and are rapidly advancing the construction of a 300,000-ton world-class PLA plant
.
Taking PLA as a starting point, from PLA to PGA, PLGA, PXA, a complete series of polyalkyd degradable materials, Donggeng provides the best process technology and Product solutions, promote the development of bio-based green degradable new materials, and make outstanding contributions to the realization of green emission reduction
.
