Hydrogen bond, I'm glad I didn't give up. Finally I see you

Recently, natural gas hydrate (commonly known as "combustible ice") has occupied the headlines of major news media Combustible ice is a hydrogen bonded crystal formed by eight water molecules and one methane at low temperature and high pressure Hydrogen bond is a concept in the field of chemistry, which was put forward by Professor Linus Carl Pauling in 1940 Hydrogen bonds play an important role in chemical and biological systems Why can water exist as a liquid at room temperature? Who helped DNA form a double helix? These are all due to hydrogen bonding For a long time, the observation and measurement of hydrogen bonds have always been a new topic in the scientific community In 2013, researchers from the National Center for nanoscience of Chinese Academy of Sciences realized the direct imaging of intermolecular local interaction with self-made atomic force microscope For the first time in the world, the intermolecular hydrogen bond was observed directly Under ultra-high vacuum and low temperature conditions, the high-resolution image of 8-hydroxyquinoline intermolecular hydrogen bond adsorbed on the surface of copper crystal was observed, and the bond length and In addition, the coordination bond between dehydrogenated 8-hydroxyquinoline and copper atom was observed Fig.1 chemical structure of TNP and TFAP (source: Science Advanced) Fig.2 experimental observation (source: Science Advanced) Fig.3 quantitative determination of C-O ·· H-C bond (source: Science Advanced) Fig.4 simulation results of TFAP molecules (source: Science Advanced) Recently, scientists from Switzerland and Japan have studied the strength of hydrogen bond in single molecule with atomic force microscope Because the tip of the atomic force microscope is composed of carbon monoxide, when the tip is closest to these hydrogen atoms, the hydrogen bond will be formed, and its properties can also be measured By observing a propeller like compound, spiroalkane, they found that the hydrogen bond at the outermost layer of the molecule was connected by a weak C ⋅ o ⋅ h – C hydrogen bond Relevant research results have been published on science advanced recently Paper link: http://advances.sciencemag.org/content/3/5/e1603258