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Metabolism and toxicology of imidazole and thiazole drugs

 Last Update: 2021-10-10
 Source: Internet
 Author: User

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18.

Levamisole is easily absorbed from the intestine after oral administration.

There are not many tissue residues of levamisole.

The metabolic process of thiamazole in vivo is similar to that of levamisole

18.

Levamisole is less toxic

Taking this medicine, when ruminant animals are poisoned by cattle and sheep, the animal's excitability will increase, salivation, and lip licking; horse poisoning will be disturbed, fall to the ground in panic, muscle tremors all over the body, and reflexed horns; pigs and dogs will experience vomiting and coughing

At present, there are few reports on the special toxicity of levamisole at home and abroad

Thiamidazole can cause the adrenal medulla to release catecholamines and also affect the function of the central nervous system

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