Nat. Commun.: the team of Ying Yilun, associate researcher of East China University of science and technology, has made progress in controlling reversible aggregation induced luminescence process by photoelectric confinement effect

Recently, the research team of Ying Yilun, associate researcher of East China University of science and technology, has made a breakthrough in the research on the aggregation induced luminescence (AIE) effect of photoelectric confined nanopores The research results were published in nature communications under the title of "managing and visualizing the dynamic aggregation induced emission within a contracted quartz nanopore" （DOI:10.1038/s41467-018-05832-y ） 。
Based on the idea of nanopore electrochemical confinement measurement proposed in the previous stage, the research team explored and prepared a single quartz nanopore confinement photoelectric sensor interface for the challenge of reversible manipulation of the luminescent process of aiegens, which directly controlled the electrochemical reversibility of the soaring aiegens solution in the confined space at the tip of the nanopore, making AIE The luminescent body moves back and forth at a speed of 1.4-2.2 μ M / s between the confinement tip and the non confinement space, thus realizing the dynamic reversible control of the dynamic aggregation induced luminescent process at the single molecule level At the same time, the reversible process of aggregation induced luminescence in the confined space was monitored in real time and synchronously by using the transient electrochemical fluorescence technique Further, the research team used the high spatial resolution characteristics of photoelectric nano channels to inject the aiegens electrochemically into a single cell, and applied it to the fluorescence imaging analysis of a single living cell of the water-insoluble aiegens molecule This study provides a new idea for the construction of aiegens sensing mechanism with good reversibility and repeatability This thesis was led by Li Yuanjie, a first year postgraduate student, under the leadership of Ying Yilun, a young teacher of the College of chemistry After two years of unremitting efforts, Associate Professor Mei Ju helped AIE molecule preparation and synthesis The project design and measurement mechanism were carefully guided by academician Tian He and Professor Long Yitao This work is supported by the basic science center project of NSFC and the innovation research group project of NSFC.