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A new study from the University of Missouri has once again raised questions about the safety of BPA-free plastics
.
Molecular formulas of bisphenol A and bisphenol S (picture from: Wikipedia, via New Atlas)
As a chemical industrial product, bisphenol A has been widely used in the production of plastics and resins
.
BPA has been the focus of many public health debates over the past decade
.
Although different health agencies around the world are still divided on the impact of BPA exposure on human health, the increase in sales of BPA-free products has intuitively demonstrated the public's reluctance to take risks
.
To replace BPA, there are currently a variety of chemicals that can achieve similar effects
.
In view of this, just buying products based on the "BPA-free" label does not mean that it is safer
.
Cheryl Rosenfeld says synthetic chemicals like BPS can penetrate the maternal placenta, so anything circulating in the mother's blood can be easily transferred to the developing fetus
.
This mouse model is the best model we can now use to simulate the possible effects of BPS in human pregnancy, because the human placenta has a similar structure to the mouse
.
The results surprisingly showed that BPA and BPS had nearly identical effects on the animal placenta, with both chemicals altering the expression of the same 13 genes and reducing placental serotonin concentrations
.
The researchers noted that these chemicals disrupt placental serotonin production, and that reduced serotonin levels can fundamentally alter and impair fetal brain development during critical periods
.
Exposure to BPA or related substitutes during this period may have long-term adverse health consequences
.
Details of the study have been published in the recently published journal PNAS with the original title:
《Bisphenol A and bisphenol S disruptions of the mouse placenta and potential effects on the placenta–brain axis》
