Production process of 2,5-dimethoxyaniline

2,5-dimethoxyaniline (2,5-dimethoxyaniline, 2-amino-1,4-dimethoxybenzene), also known as 2-amino-1,4-dimethoxybenzene, o-amino-terephthalene, The molecular formula is C ₈ H ₁₁ NO ₂ , the molecular weight is 153.
2, and the structural formula is

1.

Light brown scaly crystal; melting point 84℃, boiling point 270℃; soluble in organic solvents and hot water, insoluble in cold water; the color turns dark when exposed to light; alkaline; this product is highly toxic, irritating the skin and mucous membranes, and can cause allergies
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2.
Production principle

Of hydroquinone with methyl chloride etherification, nitration and then, and then sodium polysulfide reduction of 2,5-dimethoxyaniline
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Dissolving pot, high pressure reactor, water washing pot (3 sets), suction filter (3 sets), sugar glass reaction pot, reduction reaction pot
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6.

1) Methylation

Add 500kg water and 226L 40% liquid caustic soda into the reaction pot, add 66kg hydroquinone under stirring, control the temperature below 35℃, and stir for 15min
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2) Nitrification

Add 505kg of water into the glass-lined reactor, add 345kg of terephthalic ether with stirring, heat to 52°C, stir for 30min to melt
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3) Restore

Add 183 kg of o-nitro-terephthalate and 200 kg of water into the reduction pot and heat to 90°C
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