[quick news] on April 9, 2019, Tsinghua University launched the action of self-improvement to let the poor students "dare to think and dare to report" to realize Tsinghua University's dream

Tsinghua University launched the self-improvement action to let the poor students "dare to think and dare to report" to realize their dream Recently, Tsinghua University launched the self-improvement action in Wenchuan middle school, Aba Prefecture, Sichuan Province The self-improvement action is an upgraded version of Tsinghua University's "self-improvement plan" In the future, it will focus on deep poverty areas such as "three districts and three prefectures" It will help more and more impoverished students realize their dream of Tsinghua University by putting policies, propaganda and training in place Yang Bin, vice president and provost of Tsinghua University, released the key points of self-improvement on the spot, and gave a lecture on "style of study and life" to middle school students in Aba Prefecture Yang Bin said that the self-improvement action is an upgraded version of the "self-improvement plan", and the focus and driving point in the future are "three regions and three states" 2019 is a crucial year to win the battle against poverty How to give full play to the role of education, play the leading and exemplary role of Tsinghua, and further strengthen efforts to enable children in rural poverty-stricken areas, especially those in "three districts and three states", to have better opportunities to receive good education, and effectively achieve the policy notice to school, implement to people, encourage principals, children and parents to dare to think and dare to report, which is the core mission of self-improvement actions Http://education.news.cn/2019-04/08/c_.htm recently, molecular biology pioneer Sydney Brenner died at the age of 92 One of Brenner's most famous achievements was the transformation of Caenorhabditis elegans into a model system for human disease research in the 1960s and 1970s, which brought a new research field To this end, he shared the 2002 Nobel Prize in physiology or medicine with biologists John Sulston and Robert Horvitz Brenner chose the worm because it is more complex than other widely studied organisms, such as bacteria, but still simple enough to be studied in depth Caenorhabditis elegans is still widely used in today's biology - Research Database PubMed data shows that about 15000 papers on the worm have been published in the past 10 years Brenner is also a co discoverer of messenger RNA These intermediate molecules transmit the cell's genetic code to the cellular mechanism that turns messenger RNA into protein Together with Francis Crick and others, he found that the genetic code of DNA consists of a series of nucleotides called codons Codons encode amino acids that make up specific proteins Over the past 35 years, he has maintained close ties with Singapore as an honorary citizen and helped set up a medical research system in Singapore On April 5, the Singapore Institute of science and technology announced his death Http://news.sciencenet.cn/htmlnews/2019/4/424959.shtm Yao Yonggang, the Kunming Animal Research Institute of the Chinese Academy of Sciences, has elucidated the molecular mechanism of the nuclear receptor peroxisome alpha (PPARA) agonist, gerfzox and pimiione, in the treatment of Alzheimer's disease The results were published in autophagy recently Yao Yonggang's research group carried out systematic research from the aspects of molecule, cell and mouse animal model At the cellular level, it was found that the drugs approved by the food and Drug Administration (FDA) for the treatment of hyperlipidemia, gemfibrozil and pirinic acid, as activators of PPARa, can activate autophagy to remove a β At the level of AD mice model, gemfibrozil and pilonic acid can effectively induce the activation of astrocytes and microglia, make them gather around a β plaque, further significantly enhance the phagocytosis and degradation of a β by astrocytes and microglia, so as to improve the physiologic characteristics of a β And this effect is closely related to the occurrence of autophagy Finally, gemfibrozil and pilonic acid can significantly improve the structure and function of damaged neurons in AD mice, and significantly improve the learning and memory ability of AD mice This study provides the experimental basis for the clinical trial of gemfibrozil, an FDA approved drug for the treatment of hyperlipidemia, in the treatment of AD Https://www.tandfonline.com/doi/abs/10.1080/15548627.2019.1596488? Journalcode = kaup20 intestinal microbiome may be able to command the immune system of the body against cancer Recently, a research report published in the international journal Nature communications from sanfordburnham prebys In this paper, the researchers identified 11 kinds of bacteria, which can activate the immune system of mice and slow down the progress of melanoma In addition, the researchers also elucidated the key role of an unfolded protein response (UPR), a cellular signaling pathway that can maintain protein homeostasis UPR is often observed in melanoma patients who respond to immunocheckpoint therapy This may reveal potential markers of patient stratification Https://www.nature.com/articles/s41467-019-09525-y PET molecular image probe can realize personalized customization Professor Zhang Hong of Institute of nuclear medicine and molecular image of Zhejiang University put forward the design idea of "PET molecular image probe microfluidic modular integrated synthesis system", which lasted for 12 years In, by using the interdisciplinary advantages, we have broken through many technical problems such as the manufacturing process of high reliable organic reaction microfluidic chips, and finally realized the research and development of finished products After verification, compared with the existing large-scale equipment, the research and development achievements of Zhang Hong's team are only the size of the computer host, which reduces the key energy consumption indicators such as preparation time, solvent consumption, equipment cost by 62% to 98% Professor Zhang Hong said that the team has developed different microfluidic chip reactors, which can be manufactured for different molecular image probes by replacing microfluidic chips Each chip is like a tape, and different probes can be obtained by inserting different chips http://digitalpaper.stdaily.com/http_www.kjrb.com/kjrb/html/2019-04/09/content_418791.htm?div=-1