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Mass spectrometry imaging technology is a rapidly developing molecular imaging technology in recent years.
It is widely used in imaging of biomolecules such as proteins, peptides, phospholipids, amino acids, and oligosaccharides
.
Carbonaceous aerosols, such as soot, black carbon, and diesel engine particles produced by incomplete combustion of biomass or fossil fuels, are usually important components of complex atmospheric particulates such as PM 2.
2.
Recently, the research group used the nanomaterial mass spectrometry imaging method established in the early stage to realize the multi-component imaging study of atmospheric carbonaceous aerosol particulate matter (PM 2.
5 ) in mouse lungs, and obtained the organic carbon in carbonaceous aerosol (OC ) And inorganic (or elemental) carbon (EC) distribution difference
.
Quantitative results show that OC is released more in the lung parenchyma and can be cleared by the lung faster than EC
2.
Mass spectrometry imaging reveals the difference in the specific distribution of organic carbon and elemental carbon in carbonaceous aerosol particulate matter (PM 2.
2.
5