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Researchers develop new thermophilic whole bacteria-catalyzed plastic biodegradation strategy

 Last Update: 2022-08-23
 Source: Internet
 Author: User

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The metabolomics research group led by Cui Qiu, a researcher at the Qingdao Institute of Bioenergy and Processes of the Chinese Academy of Sciences, has successfully established a mature gene manipulation platform for Clostridium thermocellum, a typical thermophilic bacterium.
Arbitrary genetic modification realizes the directional construction of efficient whole-bacteria catalysts

Using Clostridium thermocellum as a chassis cell, the researchers heterologously expressed the thermophilic cutinase LCC from the branch and leaf compost metagenome in C.
thermocellum, thereby successfully establishing a thermophilic whole bacteria catalyst with PET degradation function (Fig.
1)

This work was funded by the Strategic Pilot Project of the Chinese Academy of Sciences, the National Natural Science Foundation of China, and the Natural Science Foundation of Shandong Province

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