South University of Technology develops spiral fiber artificial skin

Using polymers such as polycaprolactone as raw materials

In the operation of large wounds such as the abdomen, how to effectively avoid tissue adhesion, promote wound healing and prevent incisional hernia formation? A few days ago, the research group of Professor Chen Su of the State Key Laboratory of Materials and Chemical Engineering of Nanjing University of Technology developed a The new microfluidic spinning technology based on the principle of two-solvent phase transfer constructs an artificial skin woven from high-strength spiral fibers, which effectively solves the above problems

"Microfluidic spinning technology has great application potential in the fields of tissue engineering, artificial skin and biomedicine due to its high heat transfer and mass efficiency and precise and controllable fiber structure

"Based on the microfluidic spinning technology based on the principle of two-solvent phase transfer, we have proposed a broad-spectrum method for preparing high-strength spiral fibers for the first time

The study found that by designing the inner diameter of the internal phase exit of the microfluidic chip and the inclination angle of the chip, the helix fiber radius, pitch and amplitude can be precisely controlled

"Compared with the traditional straight fiber membrane, the spiral fiber membrane has a smaller contact area with the internal organs, which is 4% of the former

"It's like when the yarn count and density used in weaving are different, and the performance of the cloth is different

Previously, Chen Su’s research group explored the use of microfluidic airjet spinning to prepare large-area high-strength artificial skin, which has shown great potential in the repair of abdominal wall defects