The Application of SepaBean® Machine in the Field of Organic Optoelectronic Materials

Organic photoelectric materials are a kind of organic materials with photoelectric activity, which are widely used in organic light-emitting diodes (as shown in Figure 1), organic transistors, organic solar cells, organic memory and other fields Organic optoelectronic materials are usually organic molecules rich in carbon atoms and with large π conjugation system, which can be divided into small molecules and polymers Compared with inorganic materials, organic optoelectronic materials can be used to prepare flexible devices in large area by solution method In addition, organic materials have a wide range of structural composition and performance adjustment space, which can be achieved by molecular design, and can be self-assembled from bottom to top Therefore, organic optoelectronic materials are attracting more and more attention because of their inherent advantages Figure 1 An organic polymer material (quoted from reference 1) that can be used to make light-emitting diodes In order to ensure better performance in the later stage, it is necessary to improve the purity of the target compound as much as possible in the early synthesis process of the organic photoelectric material Therefore, higher requirements are put forward for the separation and purification of the synthetic product Sepabean ® machine produced by Changzhou Santai Technology Co., Ltd The rapid liquid chromatography system can achieve a single separation task from milligram to hundred gram level, greatly reducing the time required for the traditional manual glass column separation and purification, and reducing the consumption of organic solvents It provides an efficient, fast and economic solution for the separation and purification of organic optoelectronic materials synthesis products In the experiment part, we take a common organic photoelectric synthesis product as an example to separate and purify the reaction crude product Using sepabean ® machine rapid liquid chromatography system (as shown in Figure 2), we can quickly get the target product and greatly shorten the experimental process Figure 2 The sample of sepabean ® machine rapid liquid chromatography system is from a common photoelectric raw material synthesis product, and its reaction formula is shown in Figure 3 Figure 3 The reaction equation of an organic photoelectric material after the completion of the synthesis reaction, the experimental parameter settings for flash preparation and purification of the synthetic product are shown in Table 1 Table 1 Flash preparation experimental parameter instrument sepabean ® machine column 40 g sepaflash ® standard normal phase silica gel column (packing particle size 40-63 μ m, pore diameter 60 μ m, order No.: s-5101-0040) detection wavelength 254 nm; 365 nm mobile phase solvent A: n-hexane; solvent B: ethyl acetate flow rate 15 ml / min sample volume 1.0 g elution gradient column volume (CV) Results and discussion of solvent B (%) 0 015 16.5 80 18 80 in the flash preparation and purification experiment, about 18 column volumes (CVS) were run with 40g sepaflash ® standard series separation column, and the target components were collected automatically The flash preparation and separation Atlas of the sample is shown in Figure 4 The impurities before and after the target point can be effectively separated by TLC spot plate detection The whole flash preparation and purification experiment takes about 20 minutes, which can save about 70% of the time compared with manual separation and purification; the solvent consumption is about 800ml, which saves about 60% of the solvent compared with manual separation The comparison results of the two methods are shown in Figure 5 Figure 4 Flash preparation and separation Atlas of samples this application case shows that sepabean ® machine can effectively save a lot of solvents and time in the synthesis of organic photoelectric materials, thus accelerating the experimental process In addition, the system is equipped with a wide range of high-sensitivity detector (200-800 nm), which can meet the needs of customers for visible light wavelength detection Sepabean ® machine's built-in method recommendation function makes the separation setting simpler, and the standard air pump module reduces the pollution of organic solvent to the laboratory environment, thus ensuring the health and safety of laboratory personnel Therefore, sepabean ® machine rapid liquid chromatography system combined with sepaflash series preparation purification column can effectively meet the application needs of the majority of organic photoelectric materials researchers Fig 5 Comparison results of automatic method and manual method in terms of time and solvent consumption 1 Y – C Kung, S – h Hsiao, fluorescent and electronic polymers with pyrenylamine chrome, J mater Chem., 2010, 20, 5481-5492 The sepafflash ® standard silica gel column series products of Changzhou Santai Technology Co., Ltd have various specifications (see Table 2) Table 2 parameters of sepaflash ® standard silica gel column (packing: ultra pure regular silica, 40-63 μ m, 60 μ m) If you need to know the specific information of the products used in this article, please click CBG online mall