The influence of uric acid on the body

Uric acid is a by-product of normal body function Uric acid is naturally produced when purine is metabolized in the body Purine is a muscle protein produced by ingesting or decomposing its own cells through diet The normal serum uric acid level is 2.4-6.0mg/dl in women and 3.4-7.0mg/dl in men Uric acid, which the body cannot metabolize, is excreted The body lacks enzymes that break down uric acid, so they are excreted through the kidneys and intestines Under normal circumstances, 70% of uric acid is excreted through urine, and the other 30% is excreted through intestine However, in the case of renal insufficiency, most of them will be excreted through the intestine Uric acid is insoluble in water, so crystals form in the joint, urethra or subcutaneous tissue when the concentration exceeds the normal level High levels of uric acid are associated with kidney disease For example, renal failure is closely related to the higher than normal level of uric acid, and uric acid crystals may accumulate in the kidney to form kidney stones or bladder stones On the other hand, it cannot be assumed that renal disease is caused by high levels of uric acid But more uric acid can be the result of renal insufficiency High uric acid associated with gout In gout attack, uric acid crystal will deposit in the cartilage and tendon around the joint Symptoms include severe pain, redness, fever, and extreme skin sensitivity The big toe is the most common site of gout, but sometimes ankle, wrist, knee and elbow are also involved In addition, male gout incidence rate is higher than female It should be noted that gout can also occur when the uric acid level is not high, and high uric acid does not always lead to gout Therefore, other reasons cannot be ignored For example, heredity is one of the pathogenic factors Dietary, health, and genetic effects on uric acid levels and gout fatty and meat proteins, as well as diets high in poultry, fish, and other seafood are closely linked to high levels of uric acid and gout In addition, drinking alcohol, high fructose corn syrup, obesity, hunger, excessive exercise and sleep apnea are also associated with gout These foods cause the body to metabolize its own tissues and release purines into the bloodstream Researchers have found that high uric acid levels are linked to high blood pressure, diabetes and Alzheimer's, but that doesn't mean that more uric acid can cause these health problems.