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N, N-dimethylethanolamine (N, N-dimethylethanolamine) is also called 2-dimethylaminoethanol (dimethy-laminoedlanol), the molecular formula is C 4 H 11 NO, the molecular weight is 89.
1, and the structural formula is
1.
Product performance
Colorless liquid; freezing point -59℃, boiling point 135℃, viscosity 3.
8×10-3Pa·s (20℃), relative density (d 20 20 ) 0.
8879, refractive index 1.
4294, flash point 40℃; compatible with water, ethanol , Benzene, ether , acetone, etc.
are miscible; smell of ammonia; low toxicity; flammable
.
2.
Production principle
A chloroethanol etherified with a base to generate ethylene oxide , and then with dimethylamine to give dimethylaminoethanol:
3.
Process flow
4.
Technical formula (kg/t)
5.
Main equipment
Ingredients pot, reaction pot, distillation pot, vacuum distillation pot, liquid storage tank
.
6.
Production process
(1) Cool 40% dimethylamine aqueous solution to 0°C, and pass in dimethylamine gas at 0-5°C to increase its concentration to 65%-70%
.
(2) Add 32% chloroethanol to the reaction pot, gradually add 30% liquid caustic soda, dehydrohalogenate at 95°C to generate ethylene oxide
.
Pour the generated ethylene oxide into the above ≥65% dimethylamine solution and react at 10-30°C to control the amount of dimethylamine to be twice as high as the theoretical amount
(3) Chloroethanol can also be directly added dropwise to dimethylamine, the yield is 85%, the production process is: add 40% dimethylamine solution to the reaction pot, adjust the temperature to 30-40 ℃, drop 95% Chloroethanol, keep stirring at 40～60℃ for 2h
.
Heat and recover excess dimethylamine until the temperature reaches 120°C
7.
Product Standard
8.
Quality inspection
Assay: Accurately weigh 0.
6g of N,N-dimethylethanolamine sample and place it in a stoppered Erlenmeyer flask containing 50mL of absolute ethanol.
After dissolving, add 20mL of acetic anhydride
.
If it heats up, cool it with cold water and let it stand for another 30 minutes
In the formula: c——molar concentration of hydrochloric acid ethanol solution, mol/L;
V 1 ——The volume of hydrochloric acid ethanol solution consumed by the sample, mL;
V 2 ——Volume of hydrochloric acid ethanol solution used in blank, mL;
G——The mass of the sample, g
.
9.
Product use
This product is used in the manufacture of ion exchange resins, polyurethane catalysts, medicines (local anesthetic tetracaine hydrochloride, antiamines, sedatives and antihypertensive drugs, etc.
), emulsifiers, textile auxiliaries, corrosion inhibitors, dyes and paint solvents , Synthetic 763 resin and its curing agent, etc.
; also used as fuel oil additives, and acrylic acid derivatives can be used as purification flocculants for urban water fields
.
10.
Security measures
(1) The raw material chloroethanol is poisonous, and the maximum allowable concentration in the workplace is 0.
0005%
.
The intermediate ethylene oxide is toxic
(2) Sealed and packaged in plastic barrels, stored in a ventilated and dry place, and stored and transported in accordance with drug regulations
.
