Ursolic acid

Ursolic acid

Ursolic Acid

[Synonyms] ursolic acid , ursolic acid

【Structural formula】

[Molecular formula and molecular weight] C ₃₀ H ₄₈ O ₃ ; 456.

[Source] The whole plant of Rabdosia amethystoiles (Benth) Hare

【Properties】White powder

This product is soluble in methanol and ethanol , slightly soluble in acetone , slightly soluble in benzene, chloroform , ether , and almost insoluble in water and petroleum ether

Melting point: 279～283℃

Optical rotation: [α]D ₂₀ +65.

【Purity Check】

TLC

1.

Developing agent toluene- ethyl acetate -formic acid (20:4:0.

Check 10% sulfuric acid ethanol solution, bake at 105℃ until the spots are clear, check under sunlight and ultraviolet light (365nm)

2.

Developing agent cyclohexane-chloroform- ethyl acetate (20:5:8)

Check 10% sulfuric acid ethanol solution, bake at 105°C until the spots are clear, check high performance liquid chromatography under sunlight and ultraviolet light (365nm)

Chromatographic column PlatinumC ₁₈ , 5um (4.

Mobile phase acetonitrile-water- phosphoric acid (60:40:0.

Detection wavelength 210nm

Differential calorimetry

Start temperature 50℃, end temperature 300℃, heating rate 5℃/min

【Structural identification】206

3540(-OH), 1720(C=O)

EI-MS m/z: 456[M] ⁺ , 248 (100%), 207, 203, 189, 133

¹ H-NMR (C ₅ D ₅ N) δ: 0.

¹³ C-NMR (C ₅ D ₅ N) δ: 39.

【Storage】Dry and airtight
.

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