Xu'an research group of Institute of technology and biology, Hefei academy of material sciences, Chinese Academy of Sciences made progress in the study of graphene oxide antagonizing the toxicity of pollutants

How to effectively and safely reduce the toxic effect of environmental pollutants has been the focus of environmental toxicology and health Thanks to its excellent physical and chemical properties, graphene oxide, Go) shows great application prospects in the field of environmental protection: on the one hand, the nano materials related to go are applied to the detection of pollutants in the environment; on the other hand, the large specific surface area and widely distributed oxygen-containing functional groups make go have broad application prospects in the adsorption and removal of pollutants in the environment Recently, Xu'an research group of Institute of technology and biology, Hefei Institute of material science, Chinese Academy of Sciences extended the detoxification potential of go to the heavy metal arsenic (as), revealing the mechanism of go antagonizing as (III) toxicity in Caenorhabditis elegans The results showed that go could reduce the reproductive toxicity induced by as (III) under the two exposure modes of go pretreatment and go and as (III) simultaneously In addition to adsorption of as (III), go can also reduce oxidative stress and mitochondrial damage induced by as (III) in vivo by inducing protective autophagy By using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and nematode mutants with loss of function, the researchers found that go accelerated as (III) excretion from nematodes by inhibiting the expression of as (III) specific binding protein (galactose lectin-1, LEC-1) in nematodes The above work laid a foundation for further exploring the mechanism of compound exposure of go and pollutants in the environment, and also provided a new research idea for the treatment and detoxification of environmental pollutants Relevant achievements have been published online by environmental science: nano (DOI: 10.1039 / c8en00244d) The research was supported by 973 Program of national major research plan, B program of leading program of Chinese Academy of Sciences, National Natural Science Foundation and special fund of president of Hefei Research Institute.