-
Combining two "stomach" and one, opening up the blocking point in the development of cholecystokinin receptor-targeted drugs
Time of Update: 2021-09-28
The research systematically revealed the structural basis for the specific recognition of cholecystokinin receptor subtypes by a variety of peptides and small molecule ligands, clarified the molecular mechanism of ligand selectivity and receptor activation, and cracked the type A human cholecystectomy The mystery of life of the selective coupling of different G proteins to CCKAR provides important information for the development of drugs targeting this type of receptor .
-
Key iron death genes can predict the efficacy of neoadjuvant chemotherapy for breast cancer
Time of Update: 2021-09-28
The imbalance between the two may indicate the degree of iron death induced by neoadjuvant chemotherapy in breast cancer cells, and independently predict whether the patient can achieve complete pathological remission and tumor-free survival.
-
Scientists explain new ways to intervene in Alzheimer's disease
Time of Update: 2021-09-28
"Exploring natural active products with anti-neuro-inflammation can effectively prevent and alleviate Alzheimer's disease, and will help improve the health problems of the elderly .
-
Researchers provide new strategies for green tea polyphenols in the treatment of colitis
Time of Update: 2021-09-28
Based on previous studies, it was found that intestinal microbes play an important role in the occurrence and development of IUGR's enteritis, and the plant extract green tea polyphenol epicatechin gallate (EGCG) has potential beneficial effects in the defense of inflammation .
-
Precision autoimmune cell therapy is expected to become a new method of liver cancer treatment
Time of Update: 2021-09-28
Precision autoimmune cell therapy is expected to become a new method of liver cancer treatment Precision autoimmune cell therapy is expected to become a new method for the treatment
-
New results achieve precise screening of prostate cancer
Time of Update: 2021-09-28
Gu Jinlou’s team reported that a metal-organic framework with a hierarchical structure based on adjustable mesopores has achieved precise screening of prostate cancer patients (PCa) by constructing a sensor model for specific enzymatic reactions .
-
For the first time, this oral analgesic was "closed to king" Coron entered the market to grab the market
Time of Update: 2021-09-19
In recent years, the sales of pregabalin capsules have grown rapidly in physical pharmacies in Chinese cities, and it has become the TOP1 product of oral painkillers in 2020.
com shows that Pregabalin Capsules successfully surpassed in 2020 in physical pharmacies in cities in China .
-
Retail sales of more than 1 billion peptic ulcer drugs, this Hunan pharmaceutical company reviews
Time of Update: 2021-09-19
On September 9, the NMPA official website released the latest batch of drug approval information, and Hunan Nanfang Sheng Pharmaceutical’s omeprazole enteric-coated tablets were approved and passed the consistency evaluation .
-
Who are the ancestors of the CRISPR enzyme?
Time of Update: 2021-09-18
"China Science News" learned from the Massachusetts Institute of Technology and the Broad Institute of Harvard University that the protein called OMEGA (obligate mobile element guided activity) discovered by the institution's molecular biologist Zhang Feng and others may be Naturally participate in the reorganization of small fragments of bacterial genome DNA .
-
Scientists discover a new mechanism for in-situ regeneration of the cochlear "sound amplifier"
Time of Update: 2021-09-18
The Liu Zhiyong research group of the Center for Excellence in Brain Science and Intelligent Technology of the Chinese Academy of Sciences (Institute of Neuroscience) achieved the first time that the transdifferentiated support cells were Prestin-positive outer hair cells in the cochlea of an adult mouse .
-
Scientists discover a new mechanism for the regulation of breast cancer lung metastasis dormancy
Time of Update: 2021-09-18
Scientists discover a new mechanism for the regulation of breast cancer lung metastasis dormancy Scientists have discovered a new mechanism for the regulation of breast cancer lung metastasis dormancy NR2F1-AS1 regulates the molecular mechanism of breast cancer cell metastasis and dormancy through the NR2F1-ΔNp63 signaling pathway .
1038/s41467-021-25552-0 https://doi.
-
The selective recognition of kinin and its receptor activation molecular mechanism revealed
Time of Update: 2021-09-18
They reported for the first time two types of kinins, namely Des-Arg 10- kallidin and bradykinin (Bradykinin) bind to the near-atomic resolution structure of two subtype complexes of bradykinin receptors B1R and B2R, respectively, revealing the molecular mechanism of selective recognition of kinin and its receptor activation .
-
New nanodevices can be used for pancreatic tumor diagnosis and targeted therapy
Time of Update: 2021-09-18
Nano Today In cancer treatment, it is an effective method to convert the energy of radiation or non-radiation waves into reactive oxygen species (ROS) through semiconductor nanomaterials to induce tumor cell apoptosis .
-
Scientists synthesize a new type of betulinic acid anti-osteoarthritis compound
Time of Update: 2021-09-18
New types of therapeutic drugs that can relieve joint pain while improving joint structure and restore joint function have become an urgent expectation for patients with osteoarthritis .
-
Scientists have discovered that gastric cancer immune escapes "minions"
Time of Update: 2021-09-18
Scientists have discovered that gastric cancer immune escapes "minions" Scientists find "minions" for immune escape from gastric cancer Scientists find "minions" for immune escape f
-
Avocado is beneficial for women to lose fat
Time of Update: 2021-09-18
" The researchers said that they hope to carry out a follow-up study to provide participants with all the daily meals and to study other markers of intestinal health and physical health in order to have a more comprehensive understanding of the metabolic effects of avocado and determine whether there is still a difference between men and women.
-
"Journal of Diabetes" will be officially converted into an open access journal in 2022
Time of Update: 2021-09-18
The Journal of Diabetes (JDB), a medical journal owned by Wiley , will officially switch to Open Access for publication in the first issue of 2022.
-
International Alliance for Omics Data Quality Control Releases Latest Research Results
Time of Update: 2021-09-18
Through the establishment and use of a series of genomic reference materials, the International Omics Data Quality Control Consortium has implemented numerous next-generation sequencing platforms and bioinformatics methods in somatic and germline mutations, copy number variations, tumor-targeted sequencing and liquid biopsy, and single cell The performance of multiple application scenarios such as sequencing has been systematically studied .
-
"Full integration of automatic sampling performance and experience" entered the public review of Antop Awards
Time of Update: 2021-09-12
The Antop Award for "All-round integration of automatic sampling performance and experience" declared by Shimadzu has entered the public review stage .
-
The title of experimental technical talent will not be a rigid paper requirement
Time of Update: 2021-09-12
On September 3, the Ministry of Human Resources and Social Security revealed to the media that the "Guiding Opinions on Deepening the Reform of the Professional Title System for Experimental Technical Talents" was issued recently.
